Results 81 to 90 of about 18,798 (210)
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Objectives/Background This study was undertaken to evaluate patient reasons for nonadoption of migraine‐preventive medications. Despite clear recommendations and eligibility criteria for migraine‐preventive treatment by the American Headache Society and the availability of these treatments, many people with migraine are not taking appropriate ...
Jessica Ailani +9 more
wiley +1 more source
Role of brain cholecystokinin in neuronal homeostasis: rediscovering novel functions of an old neuropeptide [PDF]
Exploration of Drug ScienceCholecystokinin (CCK) is the most prevalent neuropeptide in the brain, where it affects satiety, pain modulation, memory, and anxiety. Its effects are mediated by GPCRs known as the “alimentary (gastrointestinal)” CCK1r (CCK 1 receptor) and the brain ...
Santiago J. Ballaz
doaj +1 more source
Involvement of Opioid Peptides in the Analgesic Effect of Spinal Cord Stimulation in a Rat Model of Neuropathic Pain. [PDF]
Neurosci Bull, 2022 Zhai FJ +6 more
europepmc +1 more source
Integrating gepants into clinical practice for the acute treatment of migraine
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Objective To assess the role of small‐molecule calcitonin gene–related peptide receptor antagonists (gepants) in the acute treatment of migraine, particularly in relation to triptan treatments. Background Triptans have established efficacy and are widely prescribed for the acute treatment of migraine.
Richard B. Lipton +4 more
wiley +1 more source
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Objective To highlight key factors required to optimize multi‐mechanistic approaches with oral combination treatments for the acute management of a migraine attack. Background Given the complex multi‐factorial nature of migraine, combining treatments with different mechanisms of action should improve outcomes compared to monotherapies, but ...
Stephen Silberstein, Alan M. Rapoport
wiley +1 more source
Microneedles for the treatment of migraine and orofacial pain: A narrative review
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Background Migraine is a common neurological disorder and a primary headache condition. Despite its central origin, migraine pain may be referred to the orofacial region via trigeminal pathways, resulting in phenotypic overlap with other orofacial pain (OFP) conditions.
Baicheng Cao +6 more
wiley +1 more source
Superior control of inflammatory pain by corticotropin-releasing factor receptor 1 via opioid peptides in distinct pain-relevant brain areas. [PDF]
J Neuroinflammation, 2022 Mousa SA +5 more
europepmc +1 more source
International Journal of Cosmetic Science, EarlyView.Natural antioxidants from plants, fruits, seeds and fungi combat ageing by neutralizing free radicals, boosting collagen and protecting against UV damage. Enhanced by green extraction and smart delivery systems, they offer powerful anti‐inflammatory and antimicrobial benefits.
Hossein Omidian +2 more
wiley +1 more source
Journal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 516-546, April 2025.Proliferation of the term “emotion dysregulation” in child psychopathology parallels the growing interest in processes that influence negative emotional reactivity. While it commonly refers to a clinical phenotype where intense anger leads to behavioral dyscontrol, the term implies etiology because anything that is dysregulated requires an impaired ...
Joseph C. Blader +2 more
wiley +1 more source
Interleukin-4 Induces the Release of Opioid Peptides from M1 Macrophages in Pathological Pain. [PDF]
J Neurosci, 2021 Labuz D +3 more
europepmc +1 more source