British Journal of Clinical Pharmacology, EarlyView.Aims Pain is common in patients with Crohn's disease (CD) and ulcerative colitis (UC), and a substantial proportion develop chronic opioid use (COU). We examined the persistence of COU over time and identified factors predicting persistent use. Methods This nationwide Danish cohort study included patients with an initial period of COU (definition: ≥3 ...
Bente Mertz Nørgård +6 more
wiley +1 more source
Treating Withdrawal and Pain in Inpatients With Opioid Use Disorder: A Brief Educational Intervention for Internal Medicine Residents [PDF]
, 2021 Ayako Wendy Fujita +2 more
openalex +1 more source
British Journal of Clinical Pharmacology, EarlyView.MicroRNA‐122 (miR‐122) is a sensitive biomarker for paracetamol‐induced liver injury. This study assessed the diagnostic performance of dynamic chemical labelling (DCL) combined with an immunoassay platform to quantify miR‐122 in human serum, as a proof‐of‐concept for hospital use.
Samar Alzeer +9 more
wiley +1 more source
Editorial: Opioids and opioid-use disorders
Frontiers in Pharmacology, 2023 Giordano de Guglielmo +5 more
openaire +4 more sources
Outcomes associated with hospital admissions for accidental opioid overdose in British Columbia: a retrospective cohort study [PDF]
, 2019 Richard L. Morrow +3 more
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In Vitro, In Vivo and In Silico Characterization of a Novel Kappa-Opioid Receptor Antagonist [PDF]
, 2022 Kristina Puls +6 more
openalex +1 more source
Machine learning methods for predicting adverse drug events: A systematic review
British Journal of Clinical Pharmacology, EarlyView.Abstract Predicting adverse drug events (ADEs) in outpatient settings is crucial for improving medication safety, identifying high‐risk patients and reducing health‐care costs. While traditional methods struggle with the complexity of health‐care data, machine learning (ML) models offer improved prediction capabilities; however, their effectiveness in ...
Niaz Chalabianloo +8 more
wiley +1 more source
Cannabinoid, melanocortin and opioid receptor expression on DRD1 and DRD2 subpopulations in rat striatum [PDF]
, 2014 Ralph J. A. Oude Ophuis +3 more
openalex +1 more source
A Systematic Review of Simulation Models to Track and Address the Opioid Crisis
, 2021 Magdalena Cerdá +8 more
openalex +2 more sources
The κ-opioid receptor-induced autophagy is implicated in stress-driven synaptic alterations [PDF]
, 2022 Christos Karoussiotis +6 more
openalex +1 more source