Results 101 to 110 of about 315,380 (361)
Morphine for the Treatment of Pain in Sickle Cell Disease
The Scientific World Journal, 2015 Pain is a hallmark of sickle cell disease (SCD) and its treatment remains challenging. Opioids are the major family of analgesics that are commonly used for treating severe pain.
Mihir Gupta +3 more
doaj +1 more source
Status and Rationality of Opioid Use in Lung Cancer Patients: A Single Center Retrospective Study
Chinese Journal of Lung Cancer, 2020 Background and objective Cancer pain affect the physical activity, psychological state and quality of life seriously, and even shortened the survival time of patients.
Wenjuan SUN +4 more
doaj +1 more source
Pharmacogenomics in the UK National Health Service: Progress towards implementation
British Journal of Clinical Pharmacology, EarlyView.Over the past decade there has been considerable and growing enthusiasm about the promise of using genomics to inform healthcare. In particular, using genetic data to inform prescribing practice has emerged as a compelling policy priority for health systems around the world, not least in the NHS.
John H. McDermott +3 more
wiley +1 more source
An opioid-like system regulating feeding behavior in C. elegans [PDF]
, 2015 Neuropeptides are essential for the regulation of appetite. Here we show that neuropeptides could regulate feeding in mutants that lack neurotransmission from the motor neurons that stimulate feeding muscles. We identified nlp-24 by an RNAi screen of 115
Artyukhin, Alexander B. +3 more
core +3 more sources
British Journal of Clinical Pharmacology, EarlyView.Aims Several methods exist to identify hospital admissions related to adverse drug events (ADEs). Clinical adjudication by healthcare professionals is the gold standard but is labour‐intensive. Spontaneous reporting and routinely collected healthcare data using a set of International Classification of Diseases (ICD) codes often underestimate the ...
Zuzana Juhásová +2 more
wiley +1 more source
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Adverse Effects of Opioid Dependency on Central and Peripheral Aspects of the Neuromuscular System
, 2019 Prevalence of chronic pain and health care costs have caused an escalation of opioid dependency. The current national crisis involving opioid dependency and drug overdose are growing problems that need to be addressed.
Yang, Cindy
core
British Journal of Clinical Pharmacology, EarlyView.Aims We sought to characterize adverse events and deaths associated with the use of psychoactive substances in children and adolescents. Methods Two French Addictovigilance databases were analysed: spontaneous reports and deaths over the period 2016–2021, in subjects aged 10–<18 years. An unsupervised classification was implemented on consumption data (
Hélène Peyrière +13 more
wiley +1 more source
Journal of Pain Research, 2022 Danni Zhao,1 Jonggyu Baek,1 Anne L Hume,2,3 Emily A McPhillips,1 Kate L Lapane1 1Department of Population and Quantitative Health Sciences, UMass Chan Medical School, Worcester, MA, USA; 2Department of Family Medicine, Alpert Medical School, Brown ...
Zhao D +4 more
doaj
Confronting the opioid crisis: Practical pain management and strategies: AOA 2018 critical issues symposium [PDF]
, 2019 The United States is in the midst of an opioid crisis. Clinicians have been part of the problem because of overprescribing of narcotics for perioperative pain management.
Hsu, Joseph R +4 more
core +1 more source