Results 11 to 20 of about 112,332 (264)

Maternal Methadone Destabilizes Neonatal Breathing and Desensitizes Neonates to Opioid-Induced Respiratory Frequency Depression

Frontiers in Physiology, 2021
Pregnant women and developing infants are understudied populations in the opioid crisis, despite the rise in opioid use during pregnancy. Maternal opioid use results in diverse negative outcomes for the fetus/newborn, including death; however, the ...
Austin D. Hocker, Nina R. Morrison, Matthew L. Selby, Adrianne G. Huxtable   +3 more
doaj   +1 more source

Abuse and Diversion of Immediate Release Opioid Analgesics as Compared to Extended Release Formulations in the United States. [PDF]

PLoS ONE, 2016
Therapeutic use and abuse of prescription opioids in the United States increased substantially between 1990 and 2010. The Centers for Disease Control estimated deaths related to pharmaceutical opioids reached nearly 19,000 in 2014.
Janetta L Iwanicki, S Geoff Severtson, Heather McDaniel, Andrew Rosenblum, Chunki Fong, Theodore J Cicero, Matthew S Ellis, Steven P Kurtz, Mance E Buttram, Richard C Dart   +9 more
doaj   +1 more source

Epidemiological trends in opioid-only and opioid/polysubstance-related death rates among American Indian/Alaska Native populations from 1999 to 2019: a retrospective longitudinal ecological study

BMJ Open, 2022
Objectives The rate of drug overdose deaths in the USA has more than tripled since the turn of the century, and rates are disproportionately high among the American Indian/Alaska Native (AI/AN) population.
Fares Qeadan, Erin F Madden, Nana A Mensah, Benjamin Tingey, Jalene Herron, Alexandra Hernandez-Vallant, Kamilla L Venner, Kevin English, Amruta Dixit   +8 more
doaj   +1 more source

Quantifying unused opioids following emergency and ambulatory care: A systematic review and meta‐analysis

Journal of the American College of Emergency Physicians Open, 2022
Objective To quantify unused opioids among adult and pediatric patients discharged from the emergency department (ED) or ambulatory care settings with a prescription for acute pain.
Michele P. Dyson, Kathryn Dong, William Sevcik, Samir Z. Graham, Sabrina Saba, Lisa Hartling, Samina Ali   +6 more
doaj   +1 more source

Factors related to the use of opioids as early treatment in patients with knee osteoarthritis

Arthritis Research & Therapy, 2019
Objective To examine factors related to the use of opioids as an early treatment option for knee OA patients Methods Using the Korean nationwide claim database, we selected knee OA patients between 2013 and 2015. Among them, patients without any claim of
Soo-Kyung Cho, Sun-Young Jung, Seongmi Choi, Seul Gi Im, Hyoungyoung Kim, Woo Seok Choi, Eun Jin Jang, Yoon-Kyoung Sung   +7 more
doaj   +1 more source

Real-world patterns of opioid therapy initiation in Spain, 2012–2018: A population-based, retrospective cohort study with 957,080 patients and 1,509,488 initiations

Frontiers in Pharmacology, 2022
Introduction: Europe has seen a steady increase in the use of prescription opioids, especially in non-cancer indications. Epidemiological data on the patterns of use of opioids is required to optimize prescription.
Isabel Hurtado, Isabel Hurtado, Celia Robles, Celia Robles, Salvador Peiró, Salvador Peiró, Aníbal García-Sempere, Aníbal García-Sempere, Fran Llopis-Cardona, Fran Llopis-Cardona, Francisco Sánchez-Sáez, Francisco Sánchez-Sáez, Clara Rodríguez-Bernal, Clara Rodríguez-Bernal, Gabriel Sanfélix-Gimeno, Gabriel Sanfélix-Gimeno   +15 more
doaj   +1 more source

Effects of sedatives and opioids on trigger and cycling asynchronies throughout mechanical ventilation: an observational study in a large dataset from critically ill patients

Critical Care, 2019
Background In critically ill patients, poor patient-ventilator interaction may worsen outcomes. Although sedatives are often administered to improve comfort and facilitate ventilation, they can be deleterious.
Candelaria de Haro, Rudys Magrans, Josefina López-Aguilar, Jaume Montanyà, Enrico Lena, Carles Subirà, Sol Fernandez-Gonzalo, Gemma Gomà, Rafael Fernández, Guillermo M. Albaiceta, Yoanna Skrobik, Umberto Lucangelo, Gastón Murias, Ana Ochagavia, Robert M. Kacmarek, Montserrat Rue, Lluís Blanch, for the Asynchronies in the Intensive Care Unit (ASYNICU) Group   +17 more
doaj   +1 more source

Examining prevalence and correlates of smoking opioids in British Columbia: opioids are more often smoked than injected

Substance Abuse Treatment, Prevention, and Policy, 2021
Background British Columbia (BC) is in the midst of an opioid overdose crisis. Since 2017, smoking illicit drugs has been the leading mode of drug administration causing overdose death.
Stephanie Parent, Kristi Papamihali, Brittany Graham, Jane A. Buxton   +3 more
doaj   +1 more source

A Nationwide Hospital Claims Database Analysis of Real-World Patterns of Laxative Use for Opioid-Induced Constipation in Japanese Patients with Cancer

Pain and Therapy, 2023
Introduction Opioid-induced constipation (OIC) is one of the most common side effects in patients with cancer treated with opioid analgesics. The actual use of laxatives for OIC in Japan remains unelucidated.
Takahiro Higashibata, Takaomi Kessoku, Yasuhide Morioka, Yuichi Koretaka, Hirokazu Mishima, Hidetoshi Shibahara, Yuriko Masuda, Yasushi Ichikawa, Atsushi Nakajima, Takayuki Hisanaga   +9 more
doaj   +1 more source

Profile of drug users in the residential treatment centers of Tehran, Iran [PDF]

Health Promotion Perspectives, 2019
Background: The current study aimed at determining the pattern of drug dependence and its related factors in mid-term residential treatment centers (MTRCs). Methods: The current cross-sectional study was conducted on all drug dependent people residing in
Hossein Akbari, Mohsen Roshanpajouh, Keramat Nourijelyani, Mohammad-Ali Mansournia, Afarin Rahimi-Movaghar, Kamran Yazdani   +5 more
doaj   +1 more source