Results 21 to 30 of about 469,418 (405)
Ranking the harm of non-medically used prescription opioids in the UK [PDF]
, 2015 A panel of nine experts applied multi-criteria decision analysis (MCDA) to determine the relative overall harm to users and harms to others of street heroin (injected and smoked) and eleven non-medically used prescription opioids.
Bell, James +11 more
core +4 more sources
Risk of respiratory depression with opioids and concomitant gabapentinoids. [PDF]
, 2017 Introduction:The combination of opioids and central nervous system depressants such as benzodiazepines and barbiturates has an additive effect on the frequency of oversedation and respiratory depression requiring naloxone use in hospitalized patients ...
Atayee, Rabia S +7 more
core +2 more sources
Opioids for Chronic Noncancer Pain: A Systematic Review and Meta-analysis
Journal of the American Medical Association (JAMA), 2018 Importance Harms and benefits of opioids for chronic noncancer pain remain unclear. Objective To systematically review randomized clinical trials (RCTs) of opioids for chronic noncancer pain.
J. Busse +35 more
semanticscholar +1 more source
The Evolving Overdose Epidemic: Synthetic Opioids and Rising Stimulant-Related Harms.
Epidemiologic Reviews, 2020 The opioid overdose epidemic is typically described as having occurred in 3 waves, with morbidity and mortality accruing over time principally from prescription opioids (1999-2010), heroin (2011-2013), and illicit fentanyl and other synthetic opioids ...
Christopher M Jones +3 more
semanticscholar +1 more source
Trauma and acute care surgeons report prescribing less opioids over time. [PDF]
, 2019 IntroductionConfronted with the opioid epidemic, surgeons must play a larger role to reduce risk of opioid abuse while managing acute pain. Having a better understanding of the beliefs and practices of trauma and acute care surgeons regarding discharge ...
Anderson, Jamie E +2 more
core +2 more sources
Applied Organometallic Chemistry, Volume 37, Issue 2, February 2023., 2023 The paper discusses the catalytic activity of [RuCp(H2O‐κO)(mPTA)2](CF3SO3)3 for the isomerization of the cyclic allylic alcohol 2‐cyclohexen‐1‐ol with good conversion and negligible metal losses. The complex [RuCp(H2O‐κO)(mPTA)2](CF3SO3)3·MeOH (4·MeOH) was synthesized and characterized by spectroscopic techniques and its crystal structure determined ...
Belén López‐Sánchez +3 more
wiley +1 more source
Experiences of people taking opioid medication for chronic non-malignant pain : a qualitative evidence synthesis using meta-ethnography [PDF]
, 2020 Objective To review qualitative studies on the experience of taking opioid medication for chronic non-malignant pain (CNMP) or coming off them. Design This is a qualitative evidence synthesis using a seven-step approach from the methods of meta ...
Eldabe, Sam +5 more
core +1 more source
Anaesthesia, 2019 Opioids are administered peri‐operatively for postoperative analgesia, and intra‐operatively to control the sympathetic response to surgical stimuli, frequently as a surrogate for presumed pain.
J. Frauenknecht +3 more
semanticscholar +1 more source
Adverse maternal environment alters Oprl1 variant expression in mouse hippocampus
The Anatomical Record, Volume 306, Issue 1, Page 162-175, January 2023., 2023 Abstract An adverse maternal environment (AME) and Western diet (WD) in early life predispose offspring toward cognitive impairment in humans and mice. Cognitive impairment associates with hippocampal dysfunction. An important regulator of hippocampal function is the hippocampal Nociceptin/Orphanin FQ (N/OFQ) system. Previous studies find links between
Xingrao Ke +5 more
wiley +1 more source
One evidence base; three stories: do opioids relieve chronic breathlessness? [PDF]
, 2017 Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
Bajwah, Sabrina +8 more
core +1 more source