Results 11 to 20 of about 26,493 (243)
Nano-Enhanced Optical Delivery of Multi-Characteristic Opsin Gene for Spinal Optogenetic Modulation of Pain [PDF]
BioengineeringOptogenetic modulation employs light-sensitive proteins known as opsins to regulate cellular activity. A unique therapeutic application of this technique involves modulating pain perception by selectively targeting neural pathways within the spinal cord.
Darryl Narcisse +3 more
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Insects, 2023 Expanding on previous efforts to survey the visual opsin repertoires of the Hemiptera, this study confirms that homologs of the UV- and LW-opsin subfamilies are conserved in all Hemiptera, while the B-opsin subfamily is missing from the Heteroptera and ...
Markus Friedrich
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Bat eyes have ultraviolet-sensitive cone photoreceptors. [PDF]
PLoS ONE, 2009 Mammalian retinae have rod photoreceptors for night vision and cone photoreceptors for daylight and colour vision. For colour discrimination, most mammals possess two cone populations with two visual pigments (opsins) that have absorption maxima at short
Brigitte Müller +5 more
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Stimulation-Guided AAV Delivery and Longitudinal Assessment of Optogenetic Expression in Rat Motor Nerves [PDF]
Bio-ProtocolOptogenetic stimulation of peripheral motor nerves is a promising technique for modulating neural activity via illumination of light-sensitive ion channels known as opsins. Stimulating muscle activity through this method offers many advantages, such as a
Emma Moravec, Jordan Williams
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Broad-Band Activatable White-Opsin. [PDF]
PLoS ONE, 2015 Currently, the use of optogenetic sensitization of retinal cells combined with activation/inhibition has the potential to be an alternative to retinal implants that would require electrodes inside every single neuron for high visual resolution.
Subrata Batabyal +4 more
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Science Signaling, 2011 The G protein–coupled receptor opsin acts as a phospholipid flippase.
Elizabeth M. Adler
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Molecular Biology and Evolution, 2022 Abstract Opsins, the protein moieties of animal visual photo-pigments, have emerged as moonlighting proteins with diverse, light-dependent and -independent physiological functions. This raises the need to revise some basic assumptions concerning opsin expression, structure, classification, and evolution.
Roberto Feuda +2 more
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Gene expression patterns of novel visual and non-visual opsin families in immature and mature Japanese eel males [PDF]
PeerJ, 2020 This study was carried out to identify and estimate physiological function of a new type of opsin subfamily present in the retina and whole brain tissues of Japanese eel using RNA–Seq transcriptome method.
Jun-Hwan Byun +9 more
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Current Biology, 2002 What are opsins? Opsins are generally considered members of the superfamily of G-protein coupled receptors. But not all opsins activate a G-protein. Their distinguishing features are a 7 transmembrane α-helical structure, and an ability to bind a vitamin A chromophore, retinaldehyde, using a lysine in the 7th α-helix.
Foster, Russell, Bellingham, James
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Opsins: Evolution in Waiting [PDF]
Current Biology, 2005 Complete vertebrate genome sequencing has revealed a remarkable stability and uniformity in the protein-coding gene set, which at first glance might suggest that gene duplication events are relatively rare. This may be a red herring, or at least a red cichlid, as the Lake Malawi cichlid fishes show rapid and extensive duplication and diversification of
Trezise, A. E. O., Collin, S. P.
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