Results 31 to 40 of about 58,764 (371)
Optogenetics and deep brain stimulation neurotechnologies [PDF]
, 2015 Brain neural network is composed of densely packed, intricately wired neurons whose activity patterns ultimately give rise to every behavior, thought, or emotion that we experience. Over the past decade, a novel neurotechnique, optogenetics that combines
A Berndt +58 more
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Dissecting the Neural Circuitry for Pain Modulation and Chronic Pain: Insights from Optogenetics
Neuroscience Bulletin, 2022 Pain is an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage. The processing of pain involves complicated modulation at the levels of the periphery, spinal cord, and brain ...
Fang Guo +5 more
semanticscholar +1 more source
Nature Communications, 2023 Optogenetics tools for precise temporal and spatial control of protein abundance are valuable in studying diverse complex biological processes. In the present study, we engineer a monomeric tag of stabilization upon light induction (SULI) for yeast and ...
Miaowei Mao +6 more
doaj +1 more source
Probing subthreshold dynamics of hippocampal neurons by pulsed optogenetics
Science, 2022 Understanding how excitatory (E) and inhibitory (I) inputs are integrated by neurons requires monitoring their subthreshold behavior. We probed the subthreshold dynamics using optogenetic depolarizing pulses in hippocampal neuronal assemblies in freely ...
Manuel Valero +3 more
semanticscholar +1 more source
Towards circuit optogenetics [PDF]
Current Opinion in Neurobiology, 2018 Optogenetics neuronal targeting combined with single-photon wide-field illumination has already proved its enormous potential in neuroscience, enabling the optical control of entire neuronal networks and disentangling their role in the control of specific behaviors. However, establishing how a single or a sub-set of neurons controls a specific behavior,
Chen, I-Wen +2 more
openaire +4 more sources
Three-dimensional scanless holographic optogenetics with temporal focusing (3D-SHOT). [PDF]
, 2017 Optical methods capable of manipulating neural activity with cellular resolution and millisecond precision in three dimensions will accelerate the pace of neuroscience research. Existing approaches for targeting individual neurons, however, fall short of
Adesnik, Hillel +5 more
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Whole-brain mapping of effective connectivity by fMRI with cortex-wide patterned optogenetics
Neuron, 2022 Functional magnetic resonance imaging (fMRI) with optogenetic neural manipulation is a powerful tool that enables brain-wide mapping of effective functional networks.
S. Kim +6 more
semanticscholar +1 more source
Step Sequence is a Critical Gait Parameter of Unilateral 6-OHDA Parkinson's Rat Models
Cell Transplantation, 2017 Parkinson's disease is a progressive neurological disorder, marked by the loss of dopaminergic neurons in the nigrostriatal pathway that leads to abnormal gait, rigidity, slowness of movement, and tremor.
Heather A. Baldwin +4 more
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Optical excitation and detection of neuronal activity [PDF]
, 2017 Optogenetics has emerged as an exciting tool for manipulating neural activity, which in turn, can modulate behavior in live organisms. However, detecting the response to the optical stimulation requires electrophysiology with physical contact or ...
Gillette, Martha +8 more
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Advances in Ophthalmic Optogenetics: Approaches and Applications
Biomolecules, 2022 Recent advances in optogenetics hold promise for vision restoration in degenerative eye diseases. Optogenetics refers to techniques that use light to control the cellular activity of targeted cells.
Philipp P. Prosseda +4 more
semanticscholar +1 more source