Results 211 to 220 of about 2,362,461 (350)

Goldilocks zone: Allergists' perceptions of family anxiety and investment in food allergy oral immunotherapy. [PDF]

Ann Allergy Asthma Immunol
Erol M, Kim EH, Fisher JA.
europepmc   +1 more source

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

Cancer Nexus, EarlyView.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang   +5 more
wiley   +1 more source

Application Effect of Colostrum Oral Immunotherapy in the Early Stage of Mechanical Ventilation for Very Low Birth Weight Preterm Infants. [PDF]

J Multidiscip Healthc
Li L, Lin Y, Huang T, Lin C.
europepmc   +1 more source

Oral Squamous Cell Carcinoma‐Risk Factors, Diagnosis, Treatment, and Prevention

Cancer Nexus, EarlyView.
ABSTRACT Oral squamous cell carcinoma (OSCC) usually originates from the precancerous lesions of oral mucosa and accounts for approximately 90% of oral cancers. In‐depth understanding of pathogenesis, hallmarks, and etiological factors is a crucial prerequisite for advancing the diagnosis and treatment for OSCC patients. This review aims to present the
Liping Wang, Xiaole Liu, Mengjie Chen, Ying Hu, Lilei Zhu   +4 more
wiley   +1 more source

Impact of oral immunotherapy on diversity of gut microbiota in food-allergic children. [PDF]

Pediatr Allergy Immunol
Bouabid T, Tremblay BL, Lavoie MÈ, Boucher-Lafleur AM, Gagnon-Brassard F, Bégin P, Lavoie S, Rochefort-Beaudoin C, Nuncio-Naud C, Parizeault G, Morin C, Girard C, Madore AM, Laprise C.   +13 more
europepmc   +1 more source

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

Science, 2018
B. Routy, E. Le Chatelier, L. Derosa, Connie P. M. Duong, M. Alou, Romain Daillère, Aurélie Fluckiger, M. Messaoudene, C. Rauber, M. Roberti, M. Fidelle, C. Flament, Vichnou poirier-colame, P. Opolon, C. Klein, Kristina Iribarren, Laura Mondragón, Nicolas Jacquelot, Bo Qu, Gladys Ferrere, C. Clémenson, L. Mezquita, J. R. Masip, C. Naltet, S. Brosseau, C. Kaderbhai, C. Richard, H. Rizvi, F. Levenez, N. Galleron, B. Quinquis, N. Pons, B. Ryffel, V. Minard-Colin, P. Gonin, J. Soria, E. Deutsch, Y. Loriot, F. Ghiringhelli, G. Zalcman, F. Goldwasser, B. Escudier, M. Hellmann, A. Eggermont, D. Raoult, L. Albiges, G. Kroemer, L. Zitvogel   +47 more
semanticscholar   +1 more source

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition and Cancer Risk: Insights from a Large Propensity‐Matched Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies (mAbs) lower LDL cholesterol and may influence cancer through immunomodulatory pathways. However, their effect on human cancer incidence remains unknown. We conducted a retrospective, propensity score‐matched study (Clalit Health Services, Israel, 2010–2023) comparing PCSK9 ...
Inbar Nardi Agmon, Chen Gurevitz, Tzippy Shochat, Shiri Kushnir, Guy Witberg, Amos Levi, Dan Gilon, Ran Kornowski, Paaladinesh Thavendiranathan, Husam Abdel Qadir, Zaza Iakobishvili   +10 more
wiley   +1 more source

Decreased Severity of Oral Immunotherapy Induced Gastrointestinal Eosinophilic Reactions Following Revisions in Milk-Treatment Protocol. [PDF]

Allergy
Epstein-Rigbi N, Elkan M, Tzarfati Y, Levy MB, Nachshon L, Koren Y, Katz Y, Elizur A, Goldberg MR.   +8 more
europepmc   +1 more source

Immunometabolic and Spatiotemporal Control of Tissue‐Resident Memory T Cell Biology

Barrier Immunity, EarlyView.
Tissue‐resident memory T (TRM) cells in barrier tissues provide a frontline defense against invading pathogens. Immune (Signals 1–3) and nutrient (Signal 4) cues play an integral role in directing TRM formation and heterogeneity. The spatial and temporal organization of these signals establishes durable TRM cells across tissues, enabling diverse ...
Jana L. Raynor, Hongbo Chi
wiley   +1 more source

Cardiovascular toxicity induced by TKIs in patients with chronic myeloid leukaemia: Are women and men different?

ESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.
This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo, Daniela Di Lisi, Antonio Cannatà, Federica Manfrè, Celeste Vullo, Marco Santoro, Ciro Botta, Salvatrice Mancuso, Sergio Siragusa, Alfredo Ruggero Galassi, Giuseppina Novo   +10 more
wiley   +1 more source