Results 11 to 20 of about 152,444 (307)
Frontiers in Cell and Developmental Biology, 2021 Melanoma cells exhibit increased aerobic glycolysis, which represents a major biochemical alteration associated with malignant transformation; thus, glycolytic enzymes could be exploited to selectively target cancer cells in cancer therapy.
Xia Ding +15 more
doaj +1 more source
Oncolytic Virotherapy: From Bench to Bedside
Frontiers in Cell and Developmental Biology, 2021 Oncolytic viruses are naturally occurring or genetically engineered viruses that can replicate preferentially in tumor cells and inhibit tumor growth. These viruses have been considered an effective anticancer strategy in recent years.
Ludi Yang +9 more
doaj +1 more source
Journal of Pharmaceutical Analysis, 2023 Uveal melanoma (UM) is the most frequent and life-threatening ocular malignancy in adults. Aberrant histone methylation contributes to the abnormal transcriptome during oncogenesis.
Xiang Gu +8 more
doaj +1 more source
Investigating the antiparasitic potential of the marine sesquiterpene avarone, its reduced form avarol, and the novel semisynthetic thiazinoquinone analogue thiazoavarone [PDF]
, 2020 The chemical analysis of the sponge Dysidea avara afforded the known sesquiterpene quinone avarone, along with its reduced form avarol. To further explore the role of the thiazinoquinone scaffold as an antiplasmodial, antileishmanial and antischistosomal
AIELLO, ANNA +13 more
core +1 more source
Fractal Growth on the Surface of a Planet and in Orbit around it [PDF]
, 2014 Fractals are defined as geometric shapes that exhibit symmetry of scale. This simply implies that fractal is a shape that it would still look the same even if somebody could zoom in on one of its parts an infinite number of times.
Alexiou, Athanasios +2 more
core +3 more sources
Journal of Hematology & Oncology, 2020 The novel coronavirus (2019-nCoV) is an emerging causative agent that was first described in late December 2019 and causes a severe respiratory infection in humans. Notably, many of affected patients of COVID-19 were people with malignancies.
Peiwei Chai +4 more
doaj +1 more source
Antigen receptor variable region repertoires expressed by T cells infiltrating thyroid, retroorbital, and pretibial tissue in Graves' disease [PDF]
, 1996 To date, it has remained unclear whether T cells infiltrating thyroid, retroorbital, and pretibial tissue of patients with Graves' ophthalmopathy and pretibial dermopathy represent a primary immune response that is directed against certain antigenic ...
Heufelder, Armin E. +2 more
core +1 more source
Nomogram for Preoperative Estimation of Orbit Invasion Risk in Periocular Squamous Cell Carcinoma
Frontiers in Oncology, 2020 Importance: Orbital invasion occurs in some periocular squamous cell carcinoma (SCC), compromising surgical outcomes, and prognoses of patients. To date, however, there are no validation studies on the clinical features related to orbital invasion in ...
Minyue Xie +13 more
doaj +1 more source
A Genomic Point Mutation in the Extracellular Domain of the Thyrotropin Receptor in Patients with Graves’ Ophthalmopathy [PDF]
, 1994 Orbital and pretibial fibroblasts are targets of autoimmune attack in Graves' ophthalmopathy (GO) and pretibial dermopathy (PTD). The fibroblast autoantigen involved in these peripheral manifestations of Graves' disease and the reason for the association
Bahn, Rebecca S. +3 more
core +1 more source
Biophysics Role and Biomimetic Culture Systems of ECM Stiffness in Cancer EMT
Global Challenges, 2022 Oncological diseases have become the second leading cause of death from noncommunicable diseases worldwide and a major threat to human health. With the continuous progress in cancer research, the mechanical cues from the tumor microenvironment ...
Hao Tian +4 more
doaj +1 more source