Results 11 to 20 of about 9,770,413 (326)

Oncometabolites drive tumorigenesis by enhancing protein acylation: from chromosomal remodelling to nonhistone modification

open access: yesJournal of Experimental & Clinical Cancer Research, 2022
Metabolites are intermediate products of cellular metabolism catalysed by various enzymes. Metabolic remodelling, as a biochemical fingerprint of cancer cells, causes abnormal metabolite accumulation.
Yidian Fu, Jie Yu, Fang Li, Shengfang Ge
doaj   +1 more source

Management of Unsatisfactory Postoperative Double Eyelid With Intralesional Corticosteroid Injection

open access: yesFrontiers in Medicine, 2021
Purpose: The present study was designed to observe the curative effect of early intralesional corticosteroid injection to treat unsatisfactory double eyelid.Methods: This retrospective, observational study included 30 female patients (age 22–35 years ...
Siyi Zhang   +15 more
doaj   +1 more source

Oncolytic Virotherapy: From Bench to Bedside

open access: yesFrontiers in Cell and Developmental Biology, 2021
Oncolytic viruses are naturally occurring or genetically engineered viruses that can replicate preferentially in tumor cells and inhibit tumor growth. These viruses have been considered an effective anticancer strategy in recent years.
Ludi Yang   +9 more
doaj   +1 more source

Rare Diseases of the Orbit

open access: yesLaryngo-Rhino-Otologie, 2021
Zusammenfassung Dieser Übersichtsartikel stellt eine Zusammenstellung seltener Erkrankungen der Orbita dar. Es werden angeborene Fehlbildungen und strukturelle Läsionen, entzündliche Erkrankungen, gutartige und bösartige epitheliale sowie nicht ...
U. Kisser, J. Heichel, A. Glien
semanticscholar   +1 more source

Nomogram for Preoperative Estimation of Orbit Invasion Risk in Periocular Squamous Cell Carcinoma

open access: yesFrontiers in Oncology, 2020
Importance: Orbital invasion occurs in some periocular squamous cell carcinoma (SCC), compromising surgical outcomes, and prognoses of patients. To date, however, there are no validation studies on the clinical features related to orbital invasion in ...
Minyue Xie   +13 more
doaj   +1 more source

FBXO38 regulates ocular melanoma proliferation through the PI3K-Akt signaling pathway

open access: yesShanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Objective·To investigate the effect of F-box only protein 38 (FBXO38) on the ocular melanoma proliferation and the potential regulatory pathway.Methods·Human skin cutaneous melanoma A375 and human uveal melanoma OMM2.3 cell lines with FBXO38 knockdown ...
WU Yijia   +5 more
doaj   +1 more source

Biophysics Role and Biomimetic Culture Systems of ECM Stiffness in Cancer EMT

open access: yesGlobal Challenges, 2022
Oncological diseases have become the second leading cause of death from noncommunicable diseases worldwide and a major threat to human health. With the continuous progress in cancer research, the mechanical cues from the tumor microenvironment ...
Hao Tian   +4 more
doaj   +1 more source

Sperm-Specific Glycolysis Enzyme Glyceraldehyde-3-Phosphate Dehydrogenase Regulated by Transcription Factor SOX10 to Promote Uveal Melanoma Tumorigenesis

open access: yesFrontiers in Cell and Developmental Biology, 2021
Melanoma cells exhibit increased aerobic glycolysis, which represents a major biochemical alteration associated with malignant transformation; thus, glycolytic enzymes could be exploited to selectively target cancer cells in cancer therapy.
Xia Ding   +15 more
doaj   +1 more source

Genetic alteration, RNA expression, and DNA methylation profiling of coronavirus disease 2019 (COVID-19) receptor ACE2 in malignancies: a pan-cancer analysis

open access: yesJournal of Hematology & Oncology, 2020
The novel coronavirus (2019-nCoV) is an emerging causative agent that was first described in late December 2019 and causes a severe respiratory infection in humans. Notably, many of affected patients of COVID-19 were people with malignancies.
Peiwei Chai   +4 more
doaj   +1 more source

Effects of cancer on patients with COVID-19: a systematic review and meta-analysis of 63,019 participants

open access: yesCancer Biology & Medicine, 2021
Objective: Patients with underlying diseases are more vulnerable to coronavirus disease 2019 (COVID-19). The purpose of this study was to investigate cancer incidence in patients with COVID-19 and to determine whether cancer was associated with mortality
Ludi Yang   +3 more
doaj   +1 more source

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