Results 41 to 50 of about 164,630 (292)
, 2000 Fungal infections in both their invasive and non-invasive forms can prove difficult to diagnose. The often characteristic appearances on imaging are of great assistance.
Howard, D, Lloyd, G, Lund, VJ, Savy, L
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Thymidine Kinase 1 Drives Skin Cutaneous Melanoma Malignant Progression and Metabolic Reprogramming
Frontiers in Oncology, 2022 BackgroundThymidine kinase 1 (TK1) is a cell cycle-dependent kinase that catalyzes the addition of a gamma-phosphate group to thymidine. The protumorigenic role of TK1 has been reported in various malignancies.
Sipeng Zuo +9 more
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Frontiers in Immunology, 2022 BackgroundVogt-Koyanagi-Harada (VKH) disease is an autoimmune inflammatory disorder characterized by bilateral granulomatous uveitis. The objective of this study was to identify immune hub genes involved in the pathogenesis and progression of VKH disease.
Yiqi Wang +14 more
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Clinical insights on Tolosa Hunt syndrome: a multidisciplinary approach on neurological-related symptomatology in maxillofacial region [PDF]
, 2018 Background Tolosa–Hunt syndrome (THS) related neurological symptoms are described in literature as “unilateral”, “recurrent”, “episodic”, “intense”, “severe”, “lancinating” or “stabbing” pain on the upper face and forehead and may be misdiagnosed ...
Ahmed Siddiqui, Ammar +8 more
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Toxic Tau Oligomers Modulated by Novel Curcumin Derivatives [PDF]
, 2019 The pathological aggregation and accumulation of tau, a microtubule-associated protein, is a common feature amongst more than 18 different neurodegenerative diseases that are collectively known as tauopathies.
Bucchieri, Fabio +6 more
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Evaluation of chronic ocular sequelae in patients with symblepharon caused by ocular burns [PDF]
International Journal of Ophthalmology, 2020 AIM: To evaluate chronic ocular sequelae in patients with symblepharon caused by ocular burns and propose an objective grading system. METHODS: This was a retrospective, single-center clinical study.
Liang-Bo Chen +5 more
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Sex Commonalities and Differences in Obesity-Related Alterations in Intrinsic Brain Activity and Connectivity. [PDF]
, 2018 OBJECTIVE:This study aimed to characterize obesity-related sex differences in the intrinsic activity and connectivity of the brain's reward networks. METHODS:Eighty-six women (n = 43) and men (n = 43) completed a 10-minute resting functional magnetic ...
Anderberg +44 more
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Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
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Disseminated hydatid disease in the orbit and central nervous system [PDF]
International Journal of Ophthalmology, 2021 Ming-Shen Ma +4 more
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Frontiers in Cell and Developmental Biology, 2019 Long non-coding RNAs (lncRNAs) have been identified as crucial regulators in many human cancers. Many lncRNAs show aberrant expression in cancer, and some of them play critical roles in tumor proliferation, invasion, and metastasis.
Yangfan Xu +20 more
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