Role of LEAFLESS, an AP2/ERF family transcription factor, in the regulation of trichome specialized metabolism. [PDF]
Summary Acylsugars, specialized metabolites produced by trichomes of many solanaceous species, provide protection against biotic and abiotic stresses. Many acylsugar metabolic enzymes have been identified; however, regulatory factors remain unknown.
Mandal S, Rezenom YH, McKnight TD.
europepmc +2 more sources
We investigated the genetic basis for the production of triterpenoid saponins in the medicinal plant, Ardisia kteniophylla, using transcriptome sequences and qRT‐PCR. We found that genes involved in late stages of triterpenoid saponin biosynthesis are upregulated in roots, which are traditionally regarded as the medicinal organ of the plant, compared ...
Yuyang Lei +6 more
wiley +1 more source
Biosynthesis of Secondary Metabolites Based on the Regulation of MicroRNAs
MicroRNA (miRNA), a noncoding ribonucleic acid, is considered to be important for the progression of gene expression in plants and animals by rupture or translational repression of targeted mRNAs. Many types of miRNA regulate plant metabolism, growth, and response to biotic and abiotic factors.
Rajib Hossain +15 more
wiley +1 more source
Identification of a Bipartite Jasmonate-Responsive Promoter Element in the Catharanthus roseus ORCA3 Transcription Factor Gene That Interacts Specifically with AT-Hook DNA-Binding Proteins [PDF]
Abstract Jasmonates are plant signaling molecules that play key roles in defense against certain pathogens and insects, among others, by controlling the biosynthesis of protective secondary metabolites. In Catharanthus roseus, the APETALA2-domain transcription factor ORCA3 is involved in the jasmonate-responsive activation of terpenoid ...
Débora, Vom Endt +4 more
openaire +2 more sources
Abstract Basic helix‐loop‐helix (bHLH) transcription factors (TFs) are key regulators of plant specialized metabolites, including terpenoid indole alkaloids (TIAs) in Catharanthus roseus. Two previously characterized subgroup‐IVa bHLH TFs, BIS1 (bHLH Iridoid Synthesis 1) and BIS2 regulate iridoid biosynthesis in the TIA pathway.
Sanjay Kumar Singh +5 more
wiley +1 more source
GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway [PDF]
Steroidal glycoalkaloids (SGAs) are cholesterol-derived molecules produced by solanaceous species. They contribute to pathogen defence but are toxic to humans and considered as anti-nutritional compounds.
Aharoni, Asaph +13 more
core +1 more source
This study aimed to determine the effects of methyl jasmonate (Mj) combined with chromium (Cr) as elicitor on production of medicinal alkaloids, its antioxidant potential, and its effects on the expression of signaling and biosynthetic enzymes.
Elham KHATAEE +2 more
doaj +1 more source
The ORCA2 transcription factor plays a key role in regulation of the terpenoid indole alkaloid pathway [PDF]
Background: The terpenoid indole alkaloid (TIA) pathway leads to the production of pharmaceutically important drugs, such as the anticancer compounds vinblastine and vincristine.
Gibson, Susan +6 more
core +3 more sources
Application of recombinant DNA technology to studies on plant secondary metabolism [PDF]
This review which is concerned with the application of recombinant DNA technology to studies on plant secondary metabolism, presents the more common plant transformation strategies and shows how these genetic approaches are being used in attempts to ...
Yeoman, Michael M., Zárate, Rafael
core +1 more source
Identification of iridoid glucoside transporters in Catharanthus roseus [PDF]
Monoterpenoid indole alkaloids (MIAs) are plant defense compounds and high-value pharmaceuticals. Biosynthesis of the universal MIA precursor, secologanin, is organized between internal phloem-associated parenchyma (IPAP) and epidermis cells ...
Colinas Martinez, Maite +9 more
core +2 more sources

