Results 21 to 30 of about 313 (87)

BHLH IRIDOID SYNTHESIS 3 is a member of a bHLH gene cluster regulating terpenoid indole alkaloid biosynthesis in Catharanthus roseus

Plant Direct, Volume 5, Issue 1, January 2021., 2021
Abstract Basic helix‐loop‐helix (bHLH) transcription factors (TFs) are key regulators of plant specialized metabolites, including terpenoid indole alkaloids (TIAs) in Catharanthus roseus. Two previously characterized subgroup‐IVa bHLH TFs, BIS1 (bHLH Iridoid Synthesis 1) and BIS2 regulate iridoid biosynthesis in the TIA pathway.
Sanjay Kumar Singh, Barunava Patra, Priyanka Paul, Yongliang Liu, Sitakanta Pattanaik, Ling Yuan   +5 more
wiley   +1 more source

Chromium-induced alkaloid production in Catharanthus roseus (L.) G.Don in vitro cultured shoots and related gene expression patterns particularly for the novel gene GS

Acta Agriculturae Slovenica, 2019
This study aimed to determine the effects of methyl jasmonate (Mj) combined with chromium (Cr) as elicitor on production of medicinal alkaloids, its antioxidant potential, and its effects on the expression of signaling and biosynthetic enzymes.
Elham KHATAEE, Farah KARIMI, Khadijeh RAZAVI   +2 more
doaj   +1 more source

Effects of Adding Vindoline and MeJA on Production of Vincristine and Vinblastine, and Transcription of their Biosynthetic Genes in the Cultured CMCs of

Natural Product Communications, 2015
Vincristine and vinblastine were found by Liquid Chromatography-Mass Spectrometry (LC-MS) in Catharanthus roseus cambial meristem cells (CMCs) jointly treated with 0.25 mM vindolineand methyl jasmonate (MeJA), suggesting that C.
Wenjin Zhang, Jiazeng Yang, Jiachen Zi, Jianhua Zhu, Liyan Song, Rongmin Yu   +5 more
doaj   +1 more source

Effect of Aspergillus flavus Fungal Elicitor on the Production of Terpenoid Indole Alkaloids in Catharanthus roseus Cambial Meristematic Cells

Molecules, 2018
This study reported the inducing effect of Aspergillus flavus fungal elicitor on biosynthesis of terpenoid indole alkaloids (TIAs) in Catharanthus roseus cambial meristematic cells (CMCs) and its inducing mechanism. According to the results determined by
Chuxin Liang, Chang Chen, Pengfei Zhou, Lv Xu, Jianhua Zhu, Jincai Liang, Jiachen Zi, Rongmin Yu   +7 more
doaj   +1 more source

Function of AP2/ERF transcription factors involved in the regulation of specialized metabolism in <i>Ophiorrhiza pumila</i> revealed by transcriptomics and metabolomics

Frontiers in Plant Science, 2016
The hairy roots (HR) of Ophiorrhiza pumila produce camptothecin (CPT), a monoterpenoid indole alkaloid used as a precursor in the synthesis of chemotherapeutic drugs. O.
Nirin Udomsom, Amit Rai, Hideyuki Suzuki, Jun Okuyama, Ryosuke Imai, Tetsuya Mori, Ryo Nakabayashi, Kazuki Saito, Kazuki Saito, Mami Yamazaki   +9 more
doaj   +1 more source

Enzyme inhibitor studies reveal complex control of methyl-D-erythritol 4-phosphate (MEP) pathway enzyme expression in Catharanthus roseus.

PLoS ONE, 2013
In Catharanthus roseus, the monoterpene moiety exerts a strong flux control for monoterpene indole alkaloid (MIA) formation. Monoterpene synthesis depends on the methyl-D-erythritol 4-phosphate (MEP) pathway. Here, we have explored the regulation of this
Mei Han, Simon C Heppel, Tao Su, Jochen Bogs, Yuangang Zu, Zhigang An, Thomas Rausch   +6 more
doaj   +1 more source

Eliciting Effect of Catharanthine on the Biosynthesis of Vallesiachotamine and Isovallesiachotamine in Cambial Meristematic Cells

Natural Product Communications, 2018
Vallesiachotamine and isovallesiachotamine are pharmacologically active monoterpene indole alkaloids produced by Catharanthus roseus . However, the biosynthetic pathway for these two alkaloids has not been characterized.
Jianhua Zhu, Shuijie He, Pengfei Zhou, Jiachen Zi, Jincai Liang, Liyan Song, Rongmin Yu   +6 more
doaj   +1 more source

Genome‐Wide Identification of the AP2/ERF Gene Family Involved in Active Constituent Biosynthesis in Salvia miltiorrhiza

The Plant Genome, Volume 9, Issue 2, July 2016., 2016
Tanshinones and phenolic acids are the major bioactive constituents in the traditional medicinal crop Salvia miltiorrhiza; however, transcription factors (TFs) are seldom investigated with regard to their regulation of the biosynthesis of these compounds. Here a complete overview of the APETALA2/ethylene‐responsive factor (AP2/ERF) transcription factor
A. J. Ji, H. M. Luo, Z. C. Xu, X. Zhang, Y. J. Zhu, B. S. Liao, H. Yao, J. Y. Song, S. L. Chen   +8 more
wiley   +1 more source

Ornamental Exterior versus Therapeutic Interior of Madagascar Periwinkle (Catharanthus roseus): The Two Faces of a Versatile Herb

The Scientific World Journal, Volume 2015, Issue 1, 2015., 2015
Catharanthus roseus (L.) known as Madagascar periwinkle (MP) is a legendary medicinal plant mostly because of possessing two invaluable antitumor terpenoid indole alkaloids (TIAs), vincristine and vinblastine. The plant has also high aesthetic value as an evergreen ornamental that yields prolific blooms of splendid colors.
Naghmeh Nejat, Alireza Valdiani, David Cahill, Yee-How Tan, Mahmood Maziah, Rambod Abiri, Da C. Hao   +6 more
wiley   +1 more source

VqERF1B‐VqERF062‐VqNSTS2 transcriptional cascade enhances stilbene biosynthesis and resistance to powdery mildew in grapevine

Plant Biotechnology Journal, Volume 23, Issue 6, Page 2065-2082, June 2025.
Summary Grapes, as one of the world's oldest economic crops, are severely affected by grape powdery mildew, causing significant economic losses. As a phytoalexin against powdery mildew, stilbenes and their key synthetic gene, stilbene synthase (STS), are highly sought after by researchers.
Chaohui Yan, Wandi Liu, Ruimin Li, Guotian Liu, Yuejin Wang   +4 more
wiley   +1 more source