Results 161 to 170 of about 20,070 (218)

Global perspectives on central nervous system drug innovation: achievements, barriers, and priorities for the next decade. [PDF]

Int J Neuropsychopharmacol
Uchida H, Gobbi G, Zohar J, Young AH, Rujescu D, Huang MC, Sundram S, Atwoli L, Vukovic J, Ikeda K.   +9 more
europepmc   +1 more source

Outcompeting opioid-induced respiratory depression. [PDF]

J Thorac Dis
Andersen MJ, Parks RR, Langer TM, Burgraff NJ.   +3 more
europepmc   +1 more source

Self-Reported Adverse Events in Psychiatric Outpatients Taking Hypnotics: Higher Real-World Frequencies Than Those Listed in Package Inserts. [PDF]

Neuropsychopharmacol Rep
Akasaka F, Akasaka K, Okada K, Yamaguchi N, Haruki Y, Sadahiro S.   +5 more
europepmc   +1 more source

Long-term use of dual orexin receptor antagonists for the treatment of insomnia: a systematic review and meta-analysis. [PDF]

Arq Neuropsiquiatr
Araujo LMM, Sousa AD, Vieira CC, Abreu JPP, Conti CF, Silva MML, Oliveira MM.   +6 more
europepmc   +1 more source

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Effects of centrally administered orexin-B and orexin-A: a role for orexin-1 receptors in orexin-B-induced hyperactivity

Psychopharmacology, 2001
Orexin-A and orexin-B are hypothalamic neuropeptides derived from a 130-amino acid precursor, prepro-orexin, and are potent agonists at both the orexin-1 (OX1) and orexin-2 (OX2) receptors. Orexin-A has been ascribed a number of in vivo functions in the rat after intracerebroventricular (ICV) administration, including hyperphagia, neuroendocrine ...
Jim J Hagan, A Johns, N Upton
exaly   +3 more sources

Radioimmunoassay for orexin A

Life Sciences, 2000
A radioimmunoassay for orexin A has been developed. Anti-orexin A antiserum was raised in New Zealand white rabbits immunized with a conjugate of synthetic orexin A with bovine serum albumin. This antibody did not crossreact with orexin B, hypothalamic hormones, pituitary hormones, neuropeptides or gut hormones.
T, Mitsuma, Y, Hirooka, M, Kayama, Y, Mori, Y, Yokoi, N, Rhue, J, Ping, M, Izumi, R, Ikai, K, Adachi, T, Nogimori   +10 more
openaire   +2 more sources

Localization of orexin A and orexin B in the porcine uterus

Reproductive Biology, 2012
The presence of orexins and their receptors in gonads indicate that these hormones participate in the control of reproductive functions. The aim of the study was to compare the expression of the prepro-orexin (PPO) gene in porcine endometrium and myometrium and the intensity of OXA- and OXB-immunoreactivity in the following uterine structures ...
Anna, Nitkiewicz, Nina, Smolinska, Anna, Maleszka, Marta, Kiezun, Tadeusz, Kaminski   +4 more
openaire   +2 more sources