Results 1 to 10 of about 17,739 (247)
Melatonin treatment affects leptin and nesfatin-1 levels but not orexin-a levels in rem sleep deprived rats [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2023 Sleep contributes to the energy balance of body. This study aims to investigate how rapid eye movement (REM) sleep deprivation (SD) or recovery sleep affects rat weight and the serum levels of Nesfatin-1, Orexin-A, and Leptin; additionally, seeks to ...
Aysen CAKIR +3 more
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Effect of plasma isolated Orexin-A on the regulation of metabolites in male rats [PDF]
Iraqi Journal of Veterinary Sciences, 2021 This research includes the isolation and purification of Orexin-A from the plasma of healthy human via various biochemical techniques, it was proposed the therapeutic role of orexin on hyperlipidemia and lipid peroxidation and it has been suggested to ...
Rana F. Jasim, Thikra A. Allwsh
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GABAergic neurons in the nucleus accumbens regulate hedonic food intake via orexin-a expression in the lateral hypothalamus [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): To investigate the regulatory effects of the nucleus accumbens (NAcSh)-lateral hypothalamus (LHA) GABAergic neural pathway on palatable food (PF) intake via orexin-A expression in diet-induced obesity (DIO) rats.
Jieting Kong +10 more
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The Role of Orexin-A in Water Intake in Water-deprived Rats
The Journal of Qazvin University of Medical Sciences, 2022 Background: The lateral hypothalamus (LH), which produces orexin, is vital for body solution homeostasis. Lateral hypothalamus (LH) lesion causes adipsia and its stimulation increases water intake.
Mohammad Hossain Esmaeili +4 more
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Involvement of the Orexinergic System in Feeding
Applied Sciences, 2021 To know the processes involved in feeding, the dysregulation of hypothalamic neuropeptides promoting anorexigenic/orexigenic mechanisms must be investigated. Many neuropeptides are involved in this behavior and in overweight/obesity.
Pilar Marcos, Rafael Coveñas
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Frontiers in Cellular Neuroscience, 2022 BackgroundOrexin-A (OXA) is a polypeptide produced in the hypothalamus, which binds to specific receptors and exerts multiple physiological effects. Autophagy plays a vital role in early brain injury (EBI) after intracerebral hemorrhage (ICH).
Dexin Zhang +8 more
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Neurobiology of the Orexin System and Its Potential Role in the Regulation of Hedonic Tone
Brain Sciences, 2022 Orexin peptides comprise two neuropeptides, orexin A and orexin B, that bind two G-protein coupled receptors (GPCRs), orexin receptor 1 (OXR1) and orexin receptor 2 (OXR2).
Martin A. Katzman, Matthew P. Katzman
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Activity of putative orexin neurons during cataplexy
Molecular Brain, 2022 It is unclear why orexin-deficient animals, but not wild-type mice, show cataplexy. The current hypothesis predicts simultaneous excitation of cataplexy-inhibiting orexin neurons and cataplexy-inducing amygdala neurons.
Shi Zhou +7 more
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Brain Sciences, 2020 Functional non-retentive fecal incontinence (FNRFI) is a common problem in pediatric age. FNRFI is defined as unintended loss of stool in a 4-year-old or older child after organic causes have been excluded.
Vincenzo Monda +21 more
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Involvement of the Orexinergic System in Cancer: Antitumor Strategies and Future Perspectives
Applied Sciences, 2023 Peptides promote the mitogenesis and migration of tumor cells, and cancer cells overexpress peptide receptors. The involvement of the orexinergic system in cancer is reviewed here, including thirteen cancer types (e.g., adrenocortical adenoma, breast ...
Pilar Marcos, Rafael Coveñas
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