Psychopathological and psychodynamic hypotheses for pediatric stuttering [PDF]
, 2018 Stuttering is a common language alteration in pediatric age consisting in repetitions and blocks, which entail a break in the rhythm and melody of the speech.
Cerroni F. +23 more
core +1 more source
Orexin-A exerts equivocal role in atherosclerosis process depending on the duration of exposure : in vitro study [PDF]
, 2019 Orexin-A is a peptide hormone that plays a crucial role in feeding regulation and energy homeostasis. Diurnal intermittent fasting (DIF) has been found to increase orexin-A plasma levels during fasting hours, while Ramadan fasting which resembles DIF ...
Daskalopoulou, Aphrodite +9 more
core +1 more source
Pancreatic exocrine insufficiency after bariatric surgery [PDF]
, 2017 Morbid obesity is a lifelong disease, and all patients require complementary follow-up including nutritional surveillance by a multidisciplinary team after bariatric procedures.
Arnelo, Urban +7 more
core +1 more source
PLoS ONE, 2022 Acquired loss of hypothalamic orexin (hypocretin)-producing neurons causes the chronic sleep disorder narcolepsy-cataplexy. Orexin replacement therapy using orexin receptor agonists is expected as a mechanistic treatment for narcolepsy.
Hikari Yamamoto +12 more
doaj +1 more source
Phase II Proof-of-Concept Trial of the Orexin Receptor Antagonist Filorexant (MK-6096) in Patients with Major Depressive Disorder. [PDF]
, 2017 BackgroundWe evaluated the orexin receptor antagonist filorexant (MK-6096) for treatment augmentation in patients with major depressive disorder.MethodsWe conducted a 6-week, double-blind, placebo-controlled, parallel-group, Phase II, proof-of-concept ...
Ceesay, Paulette +9 more
core +1 more source
European Journal of Histochemistry, 2009 The presence and distribution of cells positive to orexin A (OXA) and to orexin type 2 receptor (OX2R) were investigated in the gastrointestinal tract of neonatal dogs by means of immunohistochemical techniques.
C Dall’Aglio +6 more
doaj +1 more source
Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. [PDF]
PLoS ONE, 2013 Both orexin and neurotensin are expressed in the lateral hypothalamic area (LHA) and have been implicated in the regulation of feeding, motor activity and the reward system.
Naoki Furutani +7 more
doaj +1 more source
Orexin, cardio-respiratory function and hypertension
Frontiers in Neuroscience, 2014 In this review we focus on the role of orexin in cardio-respiratory functions and its potential link to hypertension. 1) Orexin, cardiovascular function and hypertension.
Aihua eLi, Eugene E Nattie
doaj +1 more source
Synaptic interactions between perifornical lateral hypothalamic area, locus coeruleus nucleus and the oral pontine reticular nucleus are implicated in the stage succession during sleep-wakefulness cycle [PDF]
, 2013 This Document is Protected by copyright and was first published by Frontiers. All rights reserved. it is reproduced with permissionThe perifornical area in the posterior lateral hypothalamus (PeFLH) has been implicated in several physiological functions ...
Garzón, Miguel +3 more
core +3 more sources
Involvement of orexinergic system in psychiatric and neurodegenerative disorders: A scoping review
Brain Circulation, 2020 Orexin is a neuropeptide secreted from lateral hypothalamus and pre-frontal cortex concerned in the wakefulness and excitement. This study aimed to review the possible neurobiological effect of orexin.
Hayder M Al-Kuraishy +5 more
doaj +1 more source