Results 31 to 40 of about 81,886,651 (240)

Orexinergic Input to Dopaminergic Neurons of the Human Ventral Tegmental Area [PDF]

, 2013
The mesolimbic reward pathway arising from dopaminergic (DA) neurons of the ventral tegmental area (VTA) has been strongly implicated in reward processing and drug abuse.
Herczeg, László, László Herczeg, Csilla S Molnár, Péter Gergely, Hrabovszky Erik, Borsay, Beáta Á., Hrabovszky, Erik, Liposits, Zsolt, Erik Hrabovszky, Gergely Péter, Borsay Beáta Á., Gergely, Péter, Liposits Zsolt, Molnár, Csilla S., Zsolt Liposits, Molnár Csilla S., Beáta Á Borsay, Herczeg László   +17 more
core   +1 more source

Orexin-A Attenuates Inflammatory Responses in Lipopolysaccharide-Induced Neural Stem Cells by Regulating NF-KB and Phosphorylation of MAPK/P38/Erk Pathways

Journal of Inflammation Research, 2021
Wen Ye,1 Yan Yan,2 Yunliang Tang,1 Xiaoyang Dong,1 Gengfa Chen,1 Junwei Kang,1 Lianghua Huang,1 Qi Xiong,1 Zhen Feng1 1Department of Rehabilitation, The First Affiliated Hospital of Nanchang University, Nanchang City, Jiangxi Province, People’s ...
Ye W, Yan Y, Tang Y, Dong X, Chen G, Kang J, Huang L, Xiong Q, Feng Z   +8 more
doaj  

Orexin expression in different prostate histopathologic examinations: Can it be a marker for prostate cancer? A preliminary result

Urology Research and Practice, 2019
Objective: The aim of this study was to evaluate the expression of the orexin receptor in different prostate pathologies, including prostate adenocarcinoma, benign prostate hyperplasia and chronic prostatitis.
Murad Mehmet Başar, Ünsal Han, Murat Çakan, Serhan Alpcan, Halil Başar   +4 more
doaj   +1 more source

The orexin system in the enteric nervous system of the bottlenose dolphin (Tursiops truncatus). [PDF]

PLoS ONE, 2014
This study provides a general approach to the presence and possible role of orexins and their receptors in the gut (three gastric chambers and intestine) of confined environment bottlenose dolphin.
Claudia Gatta, Finizia Russo, Maria Grazia Russolillo, Ettore Varricchio, Marina Paolucci, Luciana Castaldo, Carla Lucini, Paolo de Girolamo, Bruno Cozzi, Lucianna Maruccio   +9 more
doaj   +1 more source

Dexamethasone Chemotherapy Does Not Disrupt Orexin Signaling. [PDF]

PLoS ONE, 2016
Steroid-induced sleep disturbance is a common and highly distressing morbidity for children receiving steroid chemotherapy for the treatment of pediatric acute lymphoblastic leukemia (ALL). Sleep disturbance can negatively impact overall quality of life,
David E Kram, Stephanie M Krasnow, Peter R Levasseur, Xinxia Zhu, Linda C Stork, Daniel L Marks   +5 more
doaj   +1 more source

Orexin-A controls sympathetic activity and eating behavior [PDF]

, 2014
It is extremely important for the health to understand the regulatory mechanisms of energy expenditure. These regulatory mechanisms play a central role in the pathogenesis of body weight alteration.
Tafuri D, D. , Tafuri, CHIEFFI, Sergio, V. , de Luca, De Luca V, A. , Dato, F. , Palmieri, Monda, M., Dato A, A. , Messina, V. , Monda, Palmieri F, MONDA, Marcellino, Messina A, De Blasio S, S. , de Blasio, S. , Chieffi, Monda V, Messina G, Dalia C, A. , Russo, Russo A, MESSINA, GIOVANNI, C. , Dalia   +23 more
core   +2 more sources

Bidirectional sleep-seizure interactions and orexin in a mouse model of tuberous sclerosis complex-related epilepsy. [PDF]

Epilepsia
Abstract Objective A strong bidirectional relationship exists between epilepsy and sleep, with seizures often occurring more frequently in sleep and, in turn, sleep being disrupted by seizures. However, the mechanistic basis of seizure–sleep interactions is poorly understood.
Rensing NR, Han L, Guo D, Foutz TJ, Wong M.   +4 more
europepmc   +2 more sources

Decreased cerebrospinal fluid orexin levels not associated with clinical sleep disturbance in Parkinson's disease: A retrospective study.

PLoS ONE, 2022
Patients with Parkinson's disease (PD) often suffer from sleep disturbances, including excessive daytime sleepiness (EDS) and rapid eye movement sleep behavior disorder (RBD).
Takuya Ogawa, Yuta Kajiyama, Hideaki Ishido, Shigeru Chiba, Gajanan S Revankar, Tomohito Nakano, Seira Taniguchi, Takashi Kanbayashi, Kensuke Ikenaka, Hideki Mochizuki   +9 more
doaj   +1 more source

Orexin/Hypocretin and Histamine Cross-Talk on Hypothalamic Neuron Counts in Mice

Frontiers in Neuroscience, 2021
The loss of hypothalamic neurons that produce wake-promoting orexin (hypocretin) neuropeptides is responsible for narcolepsy type 1 (NT1). While the number of histamine neurons is increased in patients with NT1, results on orexin-deficient mouse models ...
Chiara Berteotti, Viviana Lo Martire, Sara Alvente, Stefano Bastianini, Cristiano Bombardi, Gabriele Matteoli, Hiroshi Ohtsu, Jian-Sheng Lin, Alessandro Silvani, Giovanna Zoccoli   +9 more
doaj   +1 more source

Orexin Signaling: A Complex, Multifaceted Process

Frontiers in Cellular Neuroscience, 2022
The orexin system comprises two G protein-coupled receptors, OX1 and OX2 receptors (OX1R and OX2R, respectively), along with two endogenous agonists cleaved from a common precursor (prepro-orexin), orexin-A (OX-A) and orexin-B (OX-B).
Natasha C. Dale, Natasha C. Dale, Natasha C. Dale, Daniel Hoyer, Daniel Hoyer, Daniel Hoyer, Laura H. Jacobson, Laura H. Jacobson, Laura H. Jacobson, Kevin D. G. Pfleger, Kevin D. G. Pfleger, Kevin D. G. Pfleger, Kevin D. G. Pfleger, Elizabeth K. M. Johnstone, Elizabeth K. M. Johnstone, Elizabeth K. M. Johnstone, Elizabeth K. M. Johnstone   +16 more
doaj   +1 more source