Results 151 to 160 of about 13,145 (199)

Insomnia and women: exploring vulnerability, impact, and intervention. [PDF]

open access: yesSleep Breath
Kim HR   +6 more
europepmc   +1 more source

Orexin Projections and Localization of Orexin Receptors

2006
The past several years have provided important insights into the physiological significance of the central orexin system. An important component of these is an increased understanding of the unique neuroanatomy of the orexin/hypocretin system. The orexin peptides, orexin-A and orexin-B, are produced in a restricted region of the central nervous system,
Jacob N. Marcus, Joel K. Elmquist
openaire   +1 more source

Orexin and Orexin Receptors

2005
“Reverse pharmacological” approaches, i.e., ligand identification using cell lines expressing orphan receptors, combined with genetic engineering techniques, have increased our understanding of novel signaling systems in the body (1). Orexin/hypocretin is the first example of the factors that were successfully applied using such approaches (2).
openaire   +1 more source

Expression of orexin-A and orexin receptors in the kidney and the presence of orexin-A-like immunoreactivity in human urine

Peptides, 2006
Orexin-A (hypocretin-1), a neuropeptide with stimulatory actions on arousal and appetite, was originally shown to be specifically expressed in the hypothalamus. We studied expression of orexin-A and orexin receptors in the kidney and the presence of orexin-A-like immunoreactivity in human urine.
Kazuhiro, Takahashi   +7 more
openaire   +2 more sources

Orexins and Gastrointestinal Functions

Current Protein & Peptide Science, 2010
Orexin A (OXA) and orexin B (OXB) are recently discovered neuropeptides that appear to play a role in various distinct functions such as arousal and the sleep-wake cycle as well as on appetite and regulation of feeding and energy homeostasis. Orexins were first described as neuropeptides expressed by a specific population of neurons in the lateral ...
openaire   +2 more sources

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