Results 101 to 110 of about 6,131 (232)

Investigation of the “Not Better Explained” Diagnosis Criteria in Sleep Disorder Classifications: A Systematic Content Analysis and Critical Review

Journal of Sleep Research, EarlyView.
The “Not Better Explained” (NBE) criterion plays a key role in preventing diagnostic misclassification by structuring causal reasoning in sleep medicine. This systematic content analysis compares the use, wording, and excluded conditions of NBE criteria across the ICSD‐3‐TR and DSM‐5‐TR for ten major sleep disorders.
Jean‐Arthur Micoulaud‐Franchi, Vincent P. Martin, Julien Coelho, Régis Lopez, Pierre‐Alexis Geoffroy, Laure Peter‐Derex, Isabelle Lambert, Charles M. Morin, Clélia Quiles, Christophe Gauld   +9 more
wiley   +1 more source

Comparative effects of hypnotic agents on sleep architecture and respiratory outcomes in obstructive sleep apnea: A systematic review and network meta‐analysis

Psychiatry and Clinical Neurosciences, EarlyView.
Aim This network meta‐analysis of randomized controlled trials (RCTs) aimed to investigate which hypnotics are associated with the most favorable sleep architecture and respiratory outcomes in adults with obstructive sleep apnea. Methods Primary outcomes included total sleep time (TST) and apnea–hypopnea index (AHI) during TST.
Taro Kishi, Toshikazu Ikuta, Kenji Sakuma, Masakazu Hatano, Tatsuhiko Kishi, Tsuyoshi Kitajima, Nakao Iwata   +6 more
wiley   +1 more source

Lateral hypothalamic orexin and melanin-concentrating hormone neurons provide direct input to gonadotropin-releasing hormone neurons in the human. [PDF]

, 2015
Hypophysiotropic projections of gonadotropin-releasing hormone (GnRH)-synthesizing neurons form the final common output way of the hypothalamus in the neuroendocrine control of reproduction. Several peptidergic neuronal systems of the medial hypothalamus
András eHorváth, Beáta Ágnes Borsay, Csilla eMaurnyi, Erik eHrabovszky, Katalin eSkrapits, László eHerczeg, Ottó eSzenci, Vivien eKanti, Zsolt eLiposits, Zsolt eLiposits, Zsófia eSavanyú   +10 more
core   +2 more sources

Early adversity and the comorbidity between metabolic disease and psychopathology

The Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas, Patricia Pelufo Silveira   +1 more
wiley   +1 more source

Melanin-concentrating hormone neurons contribute to dysregulation of rapid eye movement sleep in narcolepsy

Neurobiology of Disease, 2018
The lateral hypothalamus contains neurons producing orexins that promote wakefulness and suppress REM sleep as well as neurons producing melanin-concentrating hormone (MCH) that likely promote REM sleep.
Fumito Naganuma, Sathyajit S. Bandaru, Gianna Absi, Carrie E. Mahoney, Thomas E. Scammell, Ramalingam Vetrivelan   +5 more
doaj   +1 more source

Evaluation of metabolism-related molecules in rat model of autism spectrum disorders. [PDF]

Exp Physiol
Abstract Autism spectrum disorders (ASD) are neurodevelopmental pathologies. Investigating both sexes is crucial for understanding sex‐specific manifestations of ASD. This study aims to examine ASD‐like behaviours and metabolic alterations in male and female rats prenatally exposed to valproic acid (VPA).
Tunçak S, Çakır A, Gören B, Kahveci N.   +3 more
europepmc   +2 more sources

Hypothalamic Integration of Metabolic, Endocrine, and Circadian Signals in Fish: Involvement in the Control of Food Intake [PDF]

, 2017
The regulation of food intake in fish is a complex process carried out through several different mechanisms in the central nervous system (CNS) with hypothalamus being the main regulatory center.
Cerdá Reverter, José M., Delgado Saavedra, María Jesús, Soengas, José L.   +2 more
core   +3 more sources

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source

Activation of LH orexin neurons and VTA dopamine neurons is involved in anesthesia/surgery-induced sleep–wake disorders and delirium-like behaviors in mice

Scientific Reports
Postoperative delirium (POD) and sleep disorders are common surgical complications with a close clinical association, suggesting shared pathophysiological mechanisms mediated by neurotransmitters and neural circuits.
Shuang Han, Kun He, Longlu Cao, Sha Li, Lining Huang   +4 more
doaj   +1 more source

The effect of CA1 administration of orexin-A on hippocampal expression of COX-2 and BDNF in a rat model of orofacial pain

Arquivos de Neuro-Psiquiatria
The neuropeptide orexin-A and its receptors are widely distributed in both hippocampal circuitry and pain transmission pathways. Objective: Involvement of the CA1 orexin 1 receptor (OX1R) on the modulation of orofacial pain and pain-induced changes in ...
Razieh Kooshki, Mehdi Abbasnejad, Saeed Esmaeili-Mahani, Maryam Raoof   +3 more
doaj   +1 more source