Results 111 to 120 of about 6,131 (232)
AMPK in the central nervous system: physiological roles and pathological implications [PDF]
, 2016 5′ AMP-activated protein kinase (AMPK) is considered the master metabolic regulator in all eukaryotes, as it maintains cellular energy homeostasis in a variety of tissues, including the brain.
Fioramonti, Marco +6 more
core +1 more source
British Journal of Pharmacology, Volume 183, Issue 7, Page 1517-1538, April 2026.Abstract Background and Purpose Alarming trends show that vaping e‐cigarettes containing synthetic cannabinoid receptor agonists, such as JWH‐018, is increasing among youth. However, the effects of these trends are unclear in both sexes. We therefore characterized the neuropharmacological effects of adolescent JWH‐018 inhalation in male and female rats.
Nicholas Pintori +7 more
wiley +1 more source
Frontiers in Neuroscience, 2014 The orexin/hypocretin neuropeptides are produced by a cluster of neurons within the lateral posterior hypothalamus and participate in neuronal regulation by activating their receptors (OX1 and OX2 receptors).
Leah eAluisio +8 more
doaj +1 more source
Studies on OX1 Orexin Receptor Coupling to Arachidonic Acid and Endocannabinoid Signaling [PDF]
, 2012 Orexin A and orexin B are hypothalamic neuropeptides secreted by a relatively small group of neurons located within the hypothalamus. Orexins bind and activate two G-protein-coupled receptors termed OX1 orexin receptor and OX2 orexin receptor.
Turunen, Pauli
core
Journal of Sleep Research, Volume 35, Issue 2, April 2026.ABSTRACT Sleep and disordered eating behaviours may be linked through physiological and psychological mechanisms; yet, no review has systematically investigated the relationship between different sleep indicators and disordered eating behaviours and cognitions outside a clinical context.
Marie‐Christine Opitz +49 more
wiley +1 more source
Narcolepsy and Orexins: An Example of Progress in Sleep Research
Frontiers in Neurology, 2011 Narcolepsy is a chronic neurodegenerative disease caused by a deficiency of orexin-producing neurons in the lateral hypothalamus (LH). It is clinically characterized by excessive daytime sleepiness and by intrusions into wakefulness of physiological ...
Alberto K De La Herrán-Arita +2 more
doaj +1 more source
新生ラットの単離脳幹脊髄標本を用いたセボフルラン、プロポフォール、レミフェンタニルによる呼吸抑制に対するオレキシンＢによる拮抗作用について [PDF]
, 2016 Orexins (hypocretins) play a crucial role in arousal, feeding, and endocrine function. We previously reported that orexin-B activated respiratory neurons in the isolated brainstem-spinal cords of neonatal rats.
梅澤 伸夫
core +1 more source
Inhibition of orexin-1/hypocretin-1 receptors inhibits yohimbine-induced reinstatement of ethanol and sucrose seeking in Long–Evans rats [PDF]
\ud RATIONALE:\ud \ud Previous studies have shown that orexin-1/hypocretin-1 receptors play a role in self-administration and cue-induced reinstatement of food, drug, and ethanol seeking.
Jemma K. Richards +6 more
core +2 more sources
Effect of orexin-B-saporin-induced lesions of the lateral hypothalamus on performance on a progressive ratio schedule [PDF]
, 2012 It has been suggested that a sub-population of orexinergic neurones whose somata lie in the lateral hypothalamic area (LHA) play an important role in regulating the reinforcing value of both food and drugs.
Body, Stephanie +5 more
core +1 more source