Results 31 to 40 of about 61,131 (327)
Acoustic Characterization of a Vessel-on-a-Chip Microfluidic System for Ultrasound-Mediated Drug Delivery [PDF]
, 2018 Ultrasound in the presence of gas-filled microbubbles can be used to enhance local uptake of drugs and genes. To study the drug delivery potential and its underlying physical and biological mechanisms, an in vitro vessel model should ideally include 3D ...
Beekers, I. (Inés) +6 more
core +10 more sources
Organ-on-a-chip Technology in Urology
Креативная хирургия и онкология, 2023 Organs-on-chips (OOC) refer to microfluidic devices used to create biomimetic systems of physiological organs. The system contains engineered or natural miniature tissues grown inside microfluidic chips.
A. G. Vardikian +4 more
doaj +1 more source
Organ-on-a-chip with integrated semitransparent organic electrodes for barrier function monitoring.
Lab on a Chip, 2023 Organs-on-a-chip (OoC) are cell culture platforms that replicate key functional units of tissues in vitro. Barrier integrity and permeability evaluation are of utmost importance when studying barrier-forming tissues.
Denise Marrero +5 more
semanticscholar +1 more source
Aggregate, 2023 Organ‐on‐a‐chip (OOC) platforms recapitulate human in vivo‐like conditions more realistically compared to many animal models and conventional two‐dimensional cell cultures.
Sajjad Rahmani Dabbagh +5 more
doaj +1 more source
Tissue Chips and Microphysiological Systems for Disease Modeling and Drug Testing
Micromachines, 2021 Tissue chips (TCs) and microphysiological systems (MPSs) that incorporate human cells are novel platforms to model disease and screen drugs and provide an alternative to traditional animal studies.
Leslie Donoghue +3 more
doaj +1 more source
Pharmaceutics, 2023 Microneedles (MNs) have been widely used in biomedical applications for drug delivery and biomarker detection purposes. Furthermore, MNs can also be used as a stand-alone tool to be combined with microfluidic devices. For that purpose, lab- or organ-on-a-
Renata Maia +4 more
semanticscholar +1 more source
Organ-on-a-chip technology for nanoparticle research [PDF]
Nano Convergence, 2021 AbstractThe last two decades have witnessed explosive growth in the field of nanoengineering and nanomedicine. In particular, engineered nanoparticles have garnered great attention due to their potential to enable new capabilities such as controlled and targeted drug delivery for treatment of various diseases.
Shawn Kang +2 more
openaire +3 more sources
Microfluidic Liver-on-a-Chip for Preclinical Drug Discovery
Pharmaceutics, 2023 Drug discovery is an expensive, long, and complex process, usually with a high degree of uncertainty. In order to improve the efficiency of drug development, effective methods are demanded to screen lead molecules and eliminate toxic compounds in the ...
Jingyu Fu, Hailong Qiu, Cherie S. Tan
doaj +1 more source
Membrane-free culture and real-time barrier integrity assessment of perfused intestinal epithelium tubes [PDF]
, 2017 In vitro models that better reflect in vivo epithelial barrier (patho-)physiology are urgently required to predict adverse drug effects. Here we introduce extracellular matrix-supported intestinal tubules in perfused microfluidic devices, exhibiting ...
A Junaid +20 more
core +7 more sources
Academic User View: Organ-on-a-Chip Technology [PDF]
Biosensors, 2022 Organ-on-a-Chip (OoC) systems bring together cell biology, engineering, and material science for creating systems that recapitulate the in vivo microenvironment of tissues and organs. The versatility of OoC systems enables in vitro models for studying physiological processes, drug development, and testing in both academia and industry.
Mathias Busek +4 more
openaire +4 more sources