Results 51 to 60 of about 2,755,367 (283)
Three-Dimensional Motion of the Organ of Corti [PDF]
Biophysical Journal, 2000 The vibration of the organ of Corti, a three-dimensional micromechanical structure that incorporates the sensory cells of the hearing organ, was measured in three mutually orthogonal directions. This was achieved by coupling the light of a laser Doppler vibrometer into the side arm of an epifluorescence microscope to measure velocity along the optical ...
Werner Hemmert +2 more
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International Archives of Otorhinolaryngology, 2015 Introduction Analysis of the suppression effect is a simple method to evaluate cochlear status and central auditory mechanisms and, more specifically, the medial olivocochlear system.
Lucieny Serra +5 more
doaj +1 more source
Technocratic model of the human auditory system [PDF]
arXiv, 2023 In this work, we investigate the phenomenon of transverse resonance and transverse standing waves that occur within the cochlea of living organisms. It is demonstrated that the predisposing factor for their occurrence is the cochlear shape, which resembles a conical acoustic tube coiled into a spiral and exhibits non-uniformities on its internal ...
arxiv
Compartmentalized and signal-selective gap junctional coupling in the hearing cochlea [PDF]
, 2006 Gap junctional intercellular communication (GJIC) plays a major role in cochlear function. Recent evidence suggests that connexin 26 (Cx26) and Cx30 are the major constituent proteins of cochlear gap junction channels, possibly in a unique heteromeric ...
Forge, A, Jagger, DJ
core +1 more source
BMJ Open Diabetes Research & Care, 2020 ObjectiveThe mechanisms underlying the association between diabetes and inner ear dysfunction are not known yet. The aim of the present study is to evaluate the impact of obesity/insulin resistance on inner ear fluid homeostasis in vivo, and to ...
Ann-Ki Pålbrink +9 more
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Role of bone morphogenetic proteins on cochlear hair cell formation: Analyses of Noggin and Bmp2 mutant mice [PDF]
, 2010 The mammalian organ of Corti of the inner ear is a highly sophisticated sensory end organ responsible for detecting sound. Noggin is a secreted glycoprotein, which antagonizes bone morphogenetic proteins 2 and 4 (Bmp2 and Bmp4).
Anderson +56 more
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Force Transmission in the Organ of Corti Micromachine [PDF]
Biophysical Journal, 2010 Auditory discrimination is limited by the performance of the cochlea whose acute sensitivity and frequency tuning are underpinned by electromechanical feedback from the outer hair cells. Two processes may underlie this feedback: voltage-driven contractility of the outer hair cell body and active motion of the hair bundle.
Robert Fettiplace, Jong-Hoon Nam
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Kinetic Membrane Model of Outer Hair Cells I: Motile Elements with Two Conformational States [PDF]
Biophys. J. volume 120, pages 122-132, 2021, 2018 The effectiveness of outer hair cells (OHCs) in amplifying the motion of the organ of Corti, and thereby contributing to the sensitivity of mammalian hearing, depends on the mechanical power output of these cells. Electromechanical coupling in OHCs, which enables these cells to convert electrical energy into mechanical energy, has been analyzed in ...
arxiv +1 more source
Deformation of the Outer Hair Cells and the Accumulation of Caveolin-2 in Connexin 26 Deficient Mice. [PDF]
PLoS ONE, 2015 Mutations in GJB2, which encodes connexin 26 (Cx26), a cochlear gap junction protein, represent a major cause of pre-lingual, non-syndromic deafness. The degeneration of the organ of Corti observed in Cx26 mutant-associated deafness is thought to be a ...
Takashi Anzai +10 more
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Biomolecules, 2022 Lipid transporter protein apolipoprotein E (APOE) has contributed to functional studies of various organ functions. Animals with ApoE knockout (KO) have been used to study atherosclerosis and hyperlipidemia while an increasing number of researchers have ...
Lu Ma +4 more
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