Results 61 to 70 of about 17,899 (265)

Comparative Cochlear Transcriptomics in Echolocating Bats and Mouse Reveals Hras as Protector Against Noise‐Induced Hearing Loss

open access: yesAdvanced Science, EarlyView.
Comparative cochlear transcriptomics of noise‐exposed bats (Miniopterus fuliginosus) and mice reveals bat‐specific protection mechanisms for noise‐induced hearing loss (NIHL), identifying Hras as a key hub regulator. Functional studies in mice show hair‐cell‐specific Hras overexpression significantly reduced hair‐cell damage and NIHL by activating the ...
Peng Chen   +9 more
wiley   +1 more source

Cochlear duct length along the outer wall vs organ of corti: Which one is relevant for the electrode array length selection and frequency mapping using Greenwood function?

open access: yesWorld Journal of Otorhinolaryngology-Head and Neck Surgery, 2019
Cochlear duct length (CDL) measurement or estimation is a hot topic for various research groups in the cochlear implant (CI) field as of today. Getting the CDL along the outer wall (LW) and organ of corti (OC) is possible but considering the clinical ...
Anandhan Dhanasingh
doaj   +1 more source

Speech Recognition with Cochlea‐Inspired In‐Sensor Computing

open access: yesAdvanced Intelligent Systems, EarlyView.
Traditional speech recognition methods rely on software‐based feature extraction that introduces latency and high energy costs, making them unsuitable for low‐power devices. A proof‐of‐concept demonstration is provided of a bioinspired tonotopic sensor for speech recognition that mimics the human cochlea, using a spiral‐shaped elastic metamaterial. The
Paolo H. Beoletto   +4 more
wiley   +1 more source

Cutting‐Edge Advancements in Physical Stimulation for Spiral Ganglion Neuron Protection and Regeneration

open access: yesAdvanced NanoBiomed Research, EarlyView.
Physical stimulation strategies have emerged as a therapeutic avenue for the regeneration of spiral ganglion neurons. This review explores diverse physical stimulation modalities—including topographical modulation, electrical stimulation, and photostimulation—each operating through distinct mechanisms to regulate SGN biological behavior. By elucidating
Yuhan Bai   +7 more
wiley   +1 more source

Organ of Corti and Stria Vascularis: Is there an Interdependence for Survival?

open access: yesPLoS ONE, 2016
Cochlear hair cells and the stria vascularis are critical for normal hearing. Hair cells transduce mechanical stimuli into electrical signals, whereas the stria is responsible for generating the endocochlear potential (EP), which is the driving force for
Huizhan Liu   +8 more
semanticscholar   +1 more source

Variability of jaw muscles in Tunisian street dogs and adaptation to skull shape

open access: yesThe Anatomical Record, EarlyView.
Abstract The impact of artificial selection on the masticatory apparatus of dogs has been poorly studied, and comparative data with dogs subjected to more natural constraints are lacking. This study explores the jaw musculature of Tunisian street dogs, which are largely free from the influence of breed‐specific selection.
Colline Brassard   +3 more
wiley   +1 more source

Deficiency of angulin-2/ILDR1, a tricellular tight junction-associated membrane protein, causes deafness with cochlear hair cell degeneration in mice. [PDF]

open access: yesPLoS ONE, 2015
Tricellular tight junctions seal the extracellular spaces of tricellular contacts, where the vertices of three epithelial cells meet, and are required for the establishment of a strong barrier function of the epithelial cellular sheet.
Tomohito Higashi   +3 more
doaj   +1 more source

A perspective from the Mesozoic: Evolutionary changes of the mammalian skull and their influence on feeding efficiency and high‐frequency hearing

open access: yesThe Anatomical Record, EarlyView.
Abstract The complex evolutionary history behind modern mammalian chewing performance and hearing function is a result of several changes in the entire skeletomuscular system of the skull and lower jaw. Lately, exciting multifunctional 3D analytical methods and kinematic simulations of feeding functions in both modern and fossil mammals and their ...
Julia A. Schultz
wiley   +1 more source

Targeted deletion of Sox10 by Wnt1-cre defects neuronal migration and projection in the mouse inner ear. [PDF]

open access: yesPLoS ONE, 2014
Sensory nerves of the brainstem are mostly composed of placode-derived neurons, neural crest-derived neurons and neural crest-derived Schwann cells. This mixed origin of cells has made it difficult to dissect interdependence for fiber guidance. Inner ear-
YanYan Mao   +3 more
doaj   +1 more source

Intraspecific variation of cochlear morphology in bowhead and beluga whales

open access: yesThe Anatomical Record, EarlyView.
Abstract The bony labyrinth of the petrosal bone, a distinctive feature of mammal skulls, is often identified in micro‐computed tomography imaging to infer species' physiological and ecological traits. When done as part of a comparative study, one individual specimen is normally considered representative of a species, and intraspecific variation is ...
John Peacock, J. G. M. Thewissen
wiley   +1 more source

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