A novel α-conotoxin, PeIA, cloned from Conus pergrandis, discriminates between Rat α9α10 and α7 nicotinic cholinergic receptors [PDF]
, 2005 The α9 and α10 nicotinic cholinergic subunits assemble to form the receptor believed to mediate synaptic transmission between efferent olivocochlear fibers and hair cells of the cochlea, one of the few examples of postsynaptic function for a non-muscle ...
Arredondo +59 more
core +1 more source
Insect Science, EarlyView.This study investigates the taxonomic and functional diversity of noctuoid moths in a protected coastal dune system in Central Italy, revealing strong ecological associations between moth assemblages and dune zonation. Differences in species composition and trait attributes, along with the presence of habitat‐exclusive species, highlight the role of ...
Micaela del Valle Rasino +5 more
wiley +1 more source
Ultrastructure of the organ of Corti in harbor seals (Phoca vitulina)
Frontiers in Marine Science, 2023 Ultrastructural descriptions of the inner ear of highly sound-dependent mammalian species are lacking and needed to gain a better understanding of the hearing sense.
Laura Rojas +8 more
doaj +1 more source
Development of the stria vascularis and potassium regulation in the human fetal cochlea : insights into hereditary sensorineural hearing loss [PDF]
, 2015 Sensorineural hearing loss (SNHL) is one of the most common congenital disorders in humans, afflicting one in every thousand newborns. The majority is of heritable origin and can be divided in syndromic and nonsyndromic forms. Knowledge of the expression
Chuva de Sousa Lopes, Susana Marina +5 more
core +2 more sources
Hybridity of mainly asexually propagating duckweeds in genus Lemna – dead end or breakthrough?
New Phytologist, EarlyView.Summary The cosmopolitan, mainly vegetatively propagating, organ‐reduced monocotyledonous aquatic duckweeds are the smallest and fastest growing angiosperms, distributed world‐wide and flower rarely in nature. Recently, we reported intra‐ and interspecific hybrids and ploidy variants in the genus Lemna.
Yuri Lee +10 more
wiley +1 more source
Retention of progenitor cell phenotype in otospheres from guinea pig and mouse cochlea
Journal of Translational Medicine, 2010 Background Culturing otospheres from dissociated organ of Corti is an appropriate starting point aiming at the development of cell therapy for hair cell loss.
Haddad Luciana A +6 more
doaj +1 more source
RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors [PDF]
, 2010 Background: Insulin-like growth factor-I (IGF-I) provides pivotal cell survival and differentiation signals during inner ear development throughout evolution.
Hortensia Sanchez-Calderon +6 more
core +7 more sources
Radiogenomics: Current Understandings and Future Perspectives
MedComm, Volume 7, Issue 2, February 2026.Radiogenomics links imaging phenotypes with genetic variations, offering potential for comprehensive understanding, cost‐effective diagnosis, and prognosis prediction to advance personalized medicine. However, its clinical application remains limited by several challenges.
Xinyu Zhang +8 more
wiley +1 more source
Biochemical and Genetic Studies of UBR3, a Ubiquitin Ligase with a Function in Olfactory and Other Sensory Systems [PDF]
, 2007 Our previous work identified E3 ubiquitin ligases, termed UBR1-UBR7, that contain the ~70-residue UBR box, a motif important for the targeting of N-end rule substrates.
Hellweg, Rainer +6 more
core +1 more source
NMNAT1 Activates Autophagy to Delay D‐Galactose‐Induced Aging in Cochlear Hair Cells
Aging Cell, Volume 25, Issue 2, February 2026.The study presents mechanistic insights into cochlear hair cells aging using cellular and explant models. The assessment into NMNAT1 regulated NAD+ metabolism, autophagy, and aging in ARHL. NMNAT1 overexpression restores autophagic activity and decelerates aging in cochlear hair cells.
Yongjie Wei +14 more
wiley +1 more source