Results 71 to 80 of about 2,755,367 (283)
Biology Open, 2015 Immunoglobulin-like domain containing receptor 1 (ILDR1) is a poorly characterized gene that was first identified in lymphoma cells. Mutations in ILDR1 are responsible for DFNB42, but the pathogenesis of hearing loss caused by ILDR1 mutations remains to ...
Qing Sang +9 more
doaj +1 more source
A.I. Robustness: a Human-Centered Perspective on Technological Challenges and Opportunities [PDF]
arXiv, 2022 Despite the impressive performance of Artificial Intelligence (AI) systems, their robustness remains elusive and constitutes a key issue that impedes large-scale adoption. Robustness has been studied in many domains of AI, yet with different interpretations across domains and contexts.
arxiv
Critical behaviour of coherence and correlation of counterpropagating twin beams [PDF]
Phys. Rev. A 93, 023837 (2016), 2015 This work analyses the temporal coherence and correlation of twin beams generated in a quasi-phase matched nonlinear crystal in a counterpropagating configuration, ranging from the low-gain regime, where counterpropagating photon pairs are generated spontaneously, to the regime of stimulated pair production, close to the MOPO (Mirrorless Optical ...
arxiv +1 more source
Advanced Science, EarlyView.Pinoresinol diglucoside, a bioactive component extracted from traditional Chinese medicine, attenuates cisplatin‐induced ototoxicity in vivo and in vitro. The protective effect is achieved by downregulation of Socs1. The present study is the first to investigate the expression and function of Socs1 in inner ear, which is known to promote ferroptosis ...
Yin Chen +12 more
wiley +1 more source
Three Dimensional Intracellular Structure of the Cochlea Using the A-O-D-O Method [PDF]
, 1991 We have observed the three-dimensional intracellular structure of the organ of Corti and the spiral ganglion of the chinchilla using the aldehyde osmium-DMSO-osmium (A-O-D-O) method, and compared our findings with previous studies in the guinea pig.
Harada, Y. +3 more
core +1 more source
AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells
Advanced Science, EarlyView.Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu +8 more
wiley +1 more source
Deficiency of angulin-2/ILDR1, a tricellular tight junction-associated membrane protein, causes deafness with cochlear hair cell degeneration in mice. [PDF]
PLoS ONE, 2015 Tricellular tight junctions seal the extracellular spaces of tricellular contacts, where the vertices of three epithelial cells meet, and are required for the establishment of a strong barrier function of the epithelial cellular sheet.
Tomohito Higashi +3 more
doaj +1 more source
Ultrastructure of the organ of Corti in harbor seals (Phoca vitulina)
Frontiers in Marine Science, 2023 Ultrastructural descriptions of the inner ear of highly sound-dependent mammalian species are lacking and needed to gain a better understanding of the hearing sense.
Laura Rojas +8 more
doaj +1 more source
Type II spiral ganglion afferent neurons drive medial olivocochlear reflex suppression of the cochlear amplifier. [PDF]
, 2015 The dynamic adjustment of hearing sensitivity and frequency selectivity is mediated by the medial olivocochlear efferent reflex, which suppresses the gain of the 'cochlear amplifier' in each ear.
Cederholm, Jennie ME +7 more
core +2 more sources
Proteins of the organ of Corti (OC) [PDF]
The Journal of the Acoustical Society of America, 1987 The majority of proteins found to date in OC were identified by immunohistological methods. While these techniques are powerful tools for localization of proteins, they frequently lack satisfactory specificity. Two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) is able to demonstrate the presence in the OC of specific subtypes of certain ...
Ruediger Thalmann +2 more
openaire +2 more sources