Results 81 to 90 of about 38,853 (217)

Expression of S100β during mouse cochlear development

European Journal of Histochemistry
In the present study, the expression of S100β was examined in the mouse cochlea from embryonic day 17 (E17) to postnatal day 32 (P32) using immunofluorescence, aiming to explore its possible role in auditory system.
Wenjing Liu, Yongchun Zhang, Cheng Liang, Lizhong Su   +3 more
doaj   +1 more source

Static length changes of cochlear outer hair cells can tune low-frequency hearing.

PLoS Computational Biology, 2018
The cochlea not only transduces sound-induced vibration into neural spikes, it also amplifies weak sound to boost its detection. Actuators of this active process are sensory outer hair cells in the organ of Corti, whereas the inner hair cells transduce ...
Nikola Ciganović, Rebecca L Warren, Batu Keçeli, Stefan Jacob, Anders Fridberger, Tobias Reichenbach   +5 more
doaj   +1 more source

Studies of intercellular Ca2+ signaling and gap-junction coupling in the developing cochlea of mouse models affected by congenital hearing loss [PDF]

, 2013
Connexin 26 (Cx26) and connexin 30 (Cx30) form gap junction channels that allow the intercellular diffusion of the Ca2+ mobilizing second messenger IP3.
Rodriguez Hernandez, Laura
core   +1 more source

Minimal basilar membrane motion in low-frequency hearing [PDF]

, 2016
Low-frequency hearing is critically important for speech and music perception, but no mechanical measurements have previously been available from inner ears with intact low-frequency parts. These regions of the cochlea may function in ways different from
Ciganovic, N, Fridberger, A, Jacques, SL, Nuttall, AL, Petrie, T, Ramamoorthy, S, Reichenbach, JDT, Wang, RK, Warren, RL, Wilson, T, Zhang, Y   +10 more
core   +1 more source

TADF Emission in Supramolecular Assemblies through Cooperativity and Polymorphism

Advanced Optical Materials, Volume 14, Issue 1, 9 January 2026.
Macroscopic self‐assembled fibers emitting orange color with thermally activated delayed fluorescence (TADF) character are obtained by using encumbered phenyl D‐A linkers in a D‐A‐D configuration. The new dye self‐assembles through a cooperative mechanism into fibers that emit light upon electrical stimulus in solution‐processed organic light‐emitting ...
Marvin Nyenhuis, Jana Lohmann, Constantin G. Daniliuc, Maximilian Niehues, Florian Boße, Chiara Botta, Umberto Giovanella, Nikos L. Doltsinis, Fabio Rizzo   +8 more
wiley   +1 more source

Speech Recognition with Cochlea‐Inspired In‐Sensor Computing

Advanced Intelligent Systems, Volume 8, Issue 1, January 2026.
Traditional speech recognition methods rely on software‐based feature extraction that introduces latency and high energy costs, making them unsuitable for low‐power devices. A proof‐of‐concept demonstration is provided of a bioinspired tonotopic sensor for speech recognition that mimics the human cochlea, using a spiral‐shaped elastic metamaterial. The
Paolo H. Beoletto, Gianluca Milano, Carlo Ricciardi, Federico Bosia, Antonio S. Gliozzi   +4 more
wiley   +1 more source

Six1 is essential for differentiation and patterning of the mammalian auditory sensory epithelium.

PLoS Genetics, 2017
The organ of Corti in the cochlea is a two-cell layered epithelium: one cell layer of mechanosensory hair cells that align into one row of inner and three rows of outer hair cells interdigitated with one cell layer of underlying supporting cells along ...
Ting Zhang, Jinshu Xu, Pascal Maire, Pin-Xian Xu   +3 more
doaj   +1 more source

Sodium-activated potassium channels shape peripheral auditory function and activity of the primary auditory neurons in mice [PDF]

, 2019
Potassium (K+) channels shape the response properties of neurons. Although enormous progress has been made to characterize K+ channels in the primary auditory neurons, the molecular identities of many of these channels and their contributions to hearing ...
Gratton, Michael Anne, Jones, Sherri M., Jones, Timothy A., Lee, Jeong Han, Park, Seojin, Pyott, Sonja J., Reijntjes, Daniël O. J., Schubert, Nick M. A., van Tuinen, Marcel, Vijayakumar, Sarath, Xia, Xiao-Ming, Yamoah, Ebenezer N.   +11 more
core   +5 more sources

Dual AAV gene therapy achieves recovery of hearing and auditory processing in a DFNB16 mouse model

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
DFNB16 is among the most prevalent forms of congenital deafness, caused by mutations in the Stereocilin gene. Although no treatment currently exists, gene therapy represents a promising curative approach. Here, we demonstrate that AAV‐mediated gene delivery in a DFNB16 mouse model restored both peripheral hearing and central auditory processing ...
Sepideh Iranfar, Sophie Bagur, Chloé Felgerolle, Maxence Cornille, Najate Benamer, Hélène Le Ribeuz, Marie Giorgi, Sara Jamali, Amel Saoudi, Marie‐José Lecomte, Vincent Michel, Brice Bathellier, Saaid Safieddine   +12 more
wiley   +1 more source

Simvastatin protects auditory hair cells from gentamicin-induced toxicity and activates Akt signaling in vitro

BMC Neuroscience, 2011
Background Inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, known as statins, are commonly used as cholesterol-lowering drugs. During the past decade, evidence has emerged that statins also have neuroprotective effects.
Brand Yves, Setz Cristian, Levano Soledad, Listyo Alwin, Chavez Eduardo, Pak Kwang, Sung Michael, Radojevic Vesna, Ryan Allen F, Bodmer Daniel   +9 more
doaj   +1 more source