Results 81 to 90 of about 38,316 (263)

Chinese Clinical Practice Guidelines for Auditory Neuropathy (gCAN)

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Auditory neuropathy (AN) is an auditory disorder that affects the function of the auditory pathway. An increasing number of AN cases have been identified with the revelation of the underlying mechanisms, the advancements of diagnostic and detecting techniques.
Chinese Multi‐Center Research Collaborative Group on Clinical Diagnosis and Intervention of Auditory Neuropathy; Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery; Society of Otorhinolaryngology Head and Neck Surgery   +43 more
wiley   +1 more source

Retention of progenitor cell phenotype in otospheres from guinea pig and mouse cochlea

open access: yesJournal of Translational Medicine, 2010
Background Culturing otospheres from dissociated organ of Corti is an appropriate starting point aiming at the development of cell therapy for hair cell loss.
Haddad Luciana A   +6 more
doaj   +1 more source

Studies of intercellular Ca2+ signaling and gap-junction coupling in the developing cochlea of mouse models affected by congenital hearing loss [PDF]

open access: yes, 2013
Connexin 26 (Cx26) and connexin 30 (Cx30) form gap junction channels that allow the intercellular diffusion of the Ca2+ mobilizing second messenger IP3.
Rodriguez Hernandez, Laura
core   +1 more source

RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors [PDF]

open access: yes, 2010
Background: Insulin-like growth factor-I (IGF-I) provides pivotal cell survival and differentiation signals during inner ear development throughout evolution.
Hortensia Sanchez-Calderon   +6 more
core   +7 more sources

A pan‐European citizen science study shows population size, climate and land use are related to biased morph ratios in the heterostylous plant Primula veris

open access: yesJournal of Ecology, EarlyView.
A large‐scale citizen science study involving thousands of cowslip (Primula veris) observations from all over Europe revealed an unexpected prevalence of S‐morphs over L‐morphs, which was influenced by climatic as well as land use factors. Furthermore, general morph ratios were often unbalanced with the strongest shifts occurring in smaller populations.
Tsipe Aavik   +40 more
wiley   +1 more source

Static length changes of cochlear outer hair cells can tune low-frequency hearing.

open access: yesPLoS Computational Biology, 2018
The cochlea not only transduces sound-induced vibration into neural spikes, it also amplifies weak sound to boost its detection. Actuators of this active process are sensory outer hair cells in the organ of Corti, whereas the inner hair cells transduce ...
Nikola Ciganović   +5 more
doaj   +1 more source

Biochemical and Genetic Studies of UBR3, a Ubiquitin Ligase with a Function in Olfactory and Other Sensory Systems [PDF]

open access: yes, 2007
Our previous work identified E3 ubiquitin ligases, termed UBR1-UBR7, that contain the ~70-residue UBR box, a motif important for the targeting of N-end rule substrates.
Hellweg, Rainer   +6 more
core   +1 more source

Chronic Low‐Level Lead Exposure Causes Auditory Impairment and Accelerates the Progression of Age‐Related Hearing Loss in C57BL/6J Mice

open access: yesAging Cell, EarlyView.
Chronic low‐concentration lead exposure accelerates the development of ARHL. Lead exposure mediates damage to cochlear sensory cells via the mitochondrial protease LONP1, leading to irreversible hearing loss. ABSTRACT Heavy metal ion exposure has become a global public health concern.
Xue Bai   +10 more
wiley   +1 more source

Expression of S100β during mouse cochlear development

open access: yesEuropean Journal of Histochemistry
In the present study, the expression of S100β was examined in the mouse cochlea from embryonic day 17 (E17) to postnatal day 32 (P32) using immunofluorescence, aiming to explore its possible role in auditory system.
Wenjing Liu   +3 more
doaj   +1 more source

Minimal basilar membrane motion in low-frequency hearing [PDF]

open access: yes, 2016
Low-frequency hearing is critically important for speech and music perception, but no mechanical measurements have previously been available from inner ears with intact low-frequency parts. These regions of the cochlea may function in ways different from
Ciganovic, N   +10 more
core   +1 more source

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