Results 71 to 80 of about 52,147 (304)

Human Organic Anion Transporter hOAT1 Forms Homooligomers [PDF]

Journal of Biological Chemistry, 2005
Human organic anion transporter hOAT1 belongs to a superfamily of organic anion transporters, which play critical roles in the body disposition of clinically important drugs, including anti-human immunodeficiency virus therapeutics, anti-tumor drugs, antibiotics, anti-hypertensives, and anti-inflammatories. To gain insight into the regulation of hOAT1,
Mei, Hong, Wen, Xu, Takeshi, Yoshida, Kunihiko, Tanaka, Donald J, Wolff, Fanfan, Zhou, Masayori, Inouye, Guofeng, You   +7 more
openaire   +2 more sources

Advancing Electronic Application of Coordination Solids: Enhancing Electron Transport and Device Integration via Surface‐Mounted MOFs (SURMOFs)

Advanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of coordination solids, enabled by the surface‐mounted metal‐organic framework (SURMOF) platform, is on the cusp of generating the organic counterpart of the epitaxy of inorganics. The programmable and sequential SURMOF protocol, optimized by machine learning (ML), is suited for accessing high‐quality thin films of ...
Zhengtao Xu, Christof Wöll, Stefan Bräse   +2 more
wiley   +1 more source

Fucoidan alleviates the hepatorenal syndrome through inhibition organic solute transporter α/β to reduce bile acids reabsorption

Current Research in Pharmacology and Drug Discovery, 2023
The high levels of bile acids are a critical factor in hepatorenal syndrome. Organic solute transporter α/β (Ostα/β) participate in bile acids reabsorption in the kidney.
Xiaojuan Zhao, Ting Yang, Jiayan Zhou, Yanli Chen, Qian Shen, Jiankang Zhang, Qianqian Qiu   +6 more
doaj   +1 more source

Impaired Clearance of Methotrexate in Organic Anion Transporter 3 (Slc22a8) Knockout Mice: A Gender Specific Impact of Reduced Folates [PDF]

, 2008
Purpose To elucidate the role of the renal basolateral transporter, Oat3, in the disposition of methotrexate. Materials and Methods Chinese hamster ovary cells expressing mouse Oat3 were used to determine kinetics and specificity of inhibition of ...
Sweet, Douglas H., VanWert, Adam L.
core   +2 more sources

Enhancing Low‐Temperature Performance of Sodium‐Ion Batteries via Anion‐Solvent Interactions

Advanced Functional Materials, EarlyView.
DOL is introduced into electrolytes as a co‐solvent, increasing slat solubility, ion conductivity, and the de‐solvent process, and forming an anion‐rich solvent shell due to its high interaction with anion. With the above virtues, the batteries using this electrolyte exhibit excellent cycling stability at low temperatures. Abstract Sodium‐ion batteries
Cheng Zheng, Qian Yao, Yanan Sun, Hongyu Lv, Zhongchao Bai, Guoliang Zhang, Nana Wang, Jian Yang   +7 more
wiley   +1 more source

Biological Distribution after Oral Administration of Radioiodine-Labeled Acetaminophen to Estimate Gastrointestinal Absorption Function via OATPs, OATs, and/or MRPs

Pharmaceutics, 2023
We evaluated the whole-body distribution of orally-administered radioiodine-125 labeled acetaminophen (125I-AP) to estimate gastrointestinal absorption of anionic drugs.
Kakeru Sato, Asuka Mizutani, Yuka Muranaka, Jianwei Yao, Masato Kobayashi, Kana Yamazaki, Ryuichi Nishii, Kodai Nishi, Takeo Nakanishi, Ikumi Tamai, Keiichi Kawai   +10 more
doaj   +1 more source

Intra- and extra-cellular excretion of carboxylates [PDF]

, 2010
Carboxylates, such as malate and citrate, are widely acknowledged to have a central role in plant metabolism. They are involved in the production of energy and its storage as well as contributing to the cellular osmolyte pool and participating in the ...
De Angeli, A, Fernie, A R, Martinoia, E, Meyer, S   +3 more
core   +1 more source

MnI‐Functionalized Covalent Organic Framework as Efficient Electrocatalyst for CO2 Reduction in a Catholyte‐Free Zero‐Gap Electrolyzer

Advanced Functional Materials, EarlyView.
This work demonstrates the successful integration of a phenanthroline‐based 2D COF with MnI catalytic sites into a catholyte‐free membrane‐electrode‐assembly cell for CO2 electroreduction. The crystalline COF actively suppresses Mn⁰–Mn⁰ dimerization, achieving a turnover frequency of 617 h⁻¹ at 2.8 V (full‐cell potential), and enabling stable operation.
Laura Spies, Marcos Eduardo G. Carmo, Gonçalves J. Marrenjo, Stephan Reuther, Patrick Ganswindt, Antonio Otavio T. Patrocinio, Thomas Bein, Osmando F. Lopes, Jenny Schneider   +8 more
wiley   +1 more source

Novel lithium Schiff-base cluster complexes as electron injectors: synthesis, crystal structure, thin film characterisation and their performance in OLEDs [PDF]

, 2012
This journal is © The Royal Society of Chemistry 2012A set of novel lithium Schiff base cluster compounds has been synthesised and characterised for the first time and tested as electron injectors in OLED devices.
Alexander J. Blake, Ames, Antipán-Lara, Arumugam Partheepan, Baigent, Begley, Bredas, Burroughes, Daniel Bailey, Endo, Gnanamoly Paramswara, Heeger, Heeger, Hung, Juan Antipan-Lara, Kathirgamanathan, Kathirgamanathan, Kathirgamanathan, Kathirgamanathan, Kathirgamanathan, Kathirgamanathan, Kathirgamanathan, Kido, Kim, Li, Maron, Muttulingham Kumaraverl, Parker, Poopathy Kathirgamanathan, Pu, Rajeswaran, Reinnke, Sasabe, Schulman, Seenivasagam Ravichandran, Sivagnanasundram Surendrakumar, Subramanium Ganeshamurugan, Sun, Tang, Valdes, Van der Pauw, van der Pauw, Van der Pauw, Vanga R. Reddy, Vincent Arkley, Wakimoto, Wong, Wu, Y. F. Chan   +48 more
core   +1 more source

Photoswitching Conduction in Framework Materials

Advanced Functional Materials, EarlyView.
This mini‐review summarizes recent advances in state‐of‐the‐art proton and electron conduction in framework materials that can be remotely and reversibly switched on and off by light. It discusses the various photoswitching conduction mechanisms and the strategies employed to enhance photoswitched conductivity.
Helmy Pacheco Hernandez, Stefan Hecht, Wolfgang Wenzel, Lars Heinke, Mariana Kozlowska   +4 more
wiley   +1 more source