Results 91 to 100 of about 2,181,867 (291)

Decreased expression of breast cancer resistance protein in the duodenum in patients with obstructive cholestasis [PDF]

open access: yes, 2006
Background/Aims: The expression of transporters involved in bile acid homeostasis is differentially regulated during obstructive cholestasis. Since the drug efflux transporter breast cancer resistance protein (BCRP) is known to transport bile acids, we ...
Beuers, Ulrich   +15 more
core   +1 more source

Digitally Printed Eco‐Friendly Electronic Devices

open access: yesAdvanced Functional Materials, EarlyView.
Fabrication of electronics using eco‐friendly materials through digital printing routes is a promising strategy for improving life cycle sustainability and reducing the environmental impacts of conventional manufacturing. This review highlights state‐of‐the‐art eco‐friendly materials, green ink formulations, various resource‐efficient digital printing ...
Nitheesh M. Nair   +5 more
wiley   +1 more source

Investigating Transporter‐Mediated Drug‐Drug Interactions Using a Physiologically Based Pharmacokinetic Model of Rosuvastatin

open access: yesCPT: Pharmacometrics & Systems Pharmacology, 2017
Rosuvastatin is a frequently used probe in transporter‐mediated drug‐drug interaction (DDI) studies. This report describes the development of a physiologically based pharmacokinetic (PBPK) model of rosuvastatin for prediction of pharmacokinetic (PK) DDIs.
Q Wang, M Zheng, T Leil
doaj   +1 more source

Identification of a novel murine organic anion transporter like protein 1 (OATLP1) expressed in the kidney [PDF]

open access: yes, 2006
The organic anion transporters (OATs) are expressed in various tissues, primarily in the kidney and liver, but they are also expressed in the placenta, small intestine, and the choroid plexus, which are all epithelial tissues that transport xenobiotics ...
이운규
core   +1 more source

Material Coupling in Hybrid Neuromorphic Devices: From Fundamentals to System‐Level Applications

open access: yesAdvanced Functional Materials, EarlyView.
Hybrid neuromorphic devices utilize heterointerfaces between emerging semiconductors, where charge transfer and trapping, ion or defect modulation, and photogating are translated into synaptic functions. This paper discusses coupling strategies that tailor interfacial electronic and ionic properties in organic semiconductors, metal oxides, two ...
Minsu So   +5 more
wiley   +1 more source

Identification of a kidney-specific mouse organic cation transporter like-1 (mOCTL1) [PDF]

open access: yes, 2007
Organic ion transporters are expressed in various tissues that transport endogenous and exogenous compounds including their metabolites. There are organic anion transporter (OAT), organic cation transporter (OCT), organic anion transporter like protein ...
이운규
core   +1 more source

Architected Bio‐Based Iontronic Skin With Dual‐Mode Pressure and Strain Sensing

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐based acrylates in combination with an ionic liquid create 3D‐printed ionogels with compositionally tuneable mechanics and ionic conductivity. Gyroid architectures amplify low‐pressure sensitivity while preserving robust strain sensing, enabling dual‐mode detection of pressure and deformation.
Maksims Jurinovs   +8 more
wiley   +1 more source

Regulation of organic anion transport in the liver.

open access: yesThe Yale journal of biology and medicine, 1997
In several liver diseases the biliary transport is disturbed, resulting in, for example, jaundice and cholestasis. Many of these symptoms can be attributed to altered regulation of hepatic transporters. Organic anion transport, mediated by the canalicular multispecific organic anion transporter (cmoat), has been extensively studied.
Roelofsen, H.   +2 more
openaire   +2 more sources

Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters

open access: yesEuropean Journal of Pharmacology, 2001
The organic anion transport system is involved in the tubular excretion of various clinically important drugs. The purpose of this study was to characterize the effects of various organic anion transport inhibitors on organic anion transport using proximal tubule cells stably expressing human organic anion transporter 1 (human-OAT1) and human-OAT3 ...
M, Takeda   +5 more
openaire   +2 more sources

Biodegradable Conductors for Implantable and Wearable Transient Bioelectronics

open access: yesAdvanced Functional Materials, EarlyView.
Biodegradable conductors are essential building blocks for transient bioelectronics, enabling temporary sensing, stimulation, and energy transfer while eliminating the need for device retrieval. This review summarizes biodegradable metals, conducting polymers, ionic conductors, and conductive composites, highlighting degradation mechanisms, material ...
Yicheng Zhu, Yijun Liu, Naoji Matsuhisa
wiley   +1 more source

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