Results 41 to 50 of about 78,532 (255)

A Novel Quantification Method for Gene-Edited Animal Detection Based on ddPCR

Biology
As gene-editing technologies continue to evolve, gene-edited products are making significant strides. These products have already been commercialized in the United States and Japan, prompting global attention to their safety and regulatory oversight ...
Kaili Wang, Yi Ji, Cheng Peng, Xiaofu Wang, Lei Yang, Hangzhen Lan, Junfeng Xu, Xiaoyun Chen   +7 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Impact of T-2 toxin on intestinal inflammation and transcriptional regulation of inflammatory response in mouse macrophages

Biochemistry and Biophysics Reports
T-2 toxin, a fungal secondary metabolite produced by toxigenic Fusarium species, poses a significant threat to grain food and feed due to its potential to cause intestinal inflammation in livestock and poultry. Macrophages play a crucial role as integral
Xinghui Yang, Xiaoli Xu, Qiuhong Zhong, Haifeng Cui, Junfeng Xu, Wei Wei   +5 more
doaj   +1 more source

Scientific Opinion on application (EFSA‐GMO‐UK‐2007‐43) for the placing on the market of herbicide tolerant genetically modified soybean 356043 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 from Pioneer

EFSA Journal, 2011
This scientific opinion is an evaluation of a risk assessment for the genetically modified herbicide tolerant soybean 356043 for food and feed uses, import and processing.
EFSA Panel on Genetically Modified Organisms (GMO)
doaj   +1 more source

Scientific Opinion updating the risk assessment conclusions and risk management recommendations on the genetically modified insect resistant maize Bt11 [PDF]

EFSA Journal, 2012
Following a request from the European Commission, the Panel on Genetically Modified Organisms of the European Food Safety Authority (EFSA GMO Panel) compiled its previous risk assessment conclusions and risk management recommendations on the genetically ...
EFSA Panel on Genetically Modified Organisms (GMO)
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Scientific Opinion updating the risk assessment conclusions and risk management recommendations on the genetically modified insect resistant maize 1507 [PDF]

EFSA Journal, 2012
<p>Following a request from the European Commission, the Panel on Genetically Modified Organisms of the European Food Safety Authority (EFSA GMO Panel) compiled its previous risk assessment conclusions and risk management recommendations on the ...
EFSA Panel on Genetically Modified Organisms (GMO)
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Development of a novel Cas13a/Cas12a-mediated 'one-pot' dual detection assay for genetically modified crops

Journal of Advanced Research
Introduction: Genetically modified (GM) crops have been widely cultivated across the world and the development of rapid, ultrasensitive, visual multiplex detection platforms that are suitable for field deployment is critical for GM organism regulation ...
Lin Ding, Xiaofu Wang, Xiaoyun Chen, Xiaoli Xu, Wei Wei, Lei Yang, Yi Ji, Jian Wu, Junfeng Xu, Cheng Peng   +9 more
doaj   +1 more source

Scientific Opinion on application (EFSA‐GMO‐NL‐2012‐108) for the placing on the market of the herbicide‐tolerant genetically modified soybean MON 87708 × MON 89788 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 from Monsanto

EFSA Journal, 2015
Single events MON 87708 and MON 89788 were combined to produce the stack two‐event soybean MON 87708 × MON 89788. The EFSA GMO Panel previously assessed the two single events and did not identify safety concerns in the context of their scope. No new data
EFSA Panel on Genetically Modified Organisms (GMO)
doaj   +1 more source