Results 51 to 60 of about 154,070 (226)

Variáveis de Contexto e Respostas à Mudança Organizacional: Testando o Papel Mediador das Atitudes

open access: yesPsicologia: Teoria e Pesquisa
RESUMONo contexto atual, a regra nas organizações passou a ser a mudança em ritmo cada vez mais acelerado, demandando constante assimilação por parte dos empregados.
Vanessa de Fátima Nery   +1 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Change and organizational change as a development strategy [PDF]

open access: yesمطالعات مدیریت بهبود و تحول, 1992
تجربیات تغییر و تحول سازمانی کشورهای در حال توسعه حاوی نکات جالب و آموزنده ای است که برای پژوهشگران این رشته و مسئولان تغییر و تحول سازمانی بسیار مفید و سازنده به نظر می رسد.
abbas mohammadzadeh
doaj  

Change, technology and higher education: are universities capable of organizational change?

open access: yesOnline Learning, 2011
Technology and change are so closely related that the use of the word innovation seems synonymous with technology in many contexts, including that of higher education.
Stephen Marshall
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Managing Organizational Change and Resistance from an Individualist vs. Collectivist Perspective [PDF]

open access: yesInternational Journal of Management, Accounting and Economics, 2015
The current research paper looked into the concept of organizational individualism and collectivism and its effect on managing change. This paper focused on the factors underlying the concepts of individualism and collectivism that influence change to ...
Ng Teng, Rashad Yazdanifard
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Organizational Transition and Change Resistance [PDF]

open access: yesTheoretical and Applied Economics, 2006
The paper focuses on the very important atopic of organizational transition and change resistance. It is divided in four parts. The first part deals with transition inevitability and its content in the change process.
Ovidiu Nicolescu, Ciprian Nicolescu
doaj   +1 more source

Psychodynamic Perspective of Organizational Change

open access: yesManagement, 2016
The complex processes and phenomena that are taking place in the contemporary world require new and adequate methods of acting also in the area of management. This means the need for a fresh approach to the process of organization development and change.
Barabasz Adela
doaj   +1 more source

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