Results 91 to 100 of about 5,005,544 (308)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Further examination of the organizational culture scale of artifacts [PDF]
The construct validity of a 10-item Organizational Culture Scale Focused on Artifacts oriented to measure traditional culture was analyzed under the unidimensionality hypothesis of the scale.
Molina, Gabriel +2 more
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
ORGANIZATIONAL CULTURE: KEY ISSUES. A LITERATURE REVIEW [PDF]
Annals of the University of Oradea: Economic Science, 2017 In the today's global, knowledge-based digital economy, the organizational culture becomes a strategic source of sustained competitive advantage. Therefore, the organizational culture is an increasingly important issue of academic research, education ...
Ilies Liviu, Metz Daniel
doaj
An examination of the organizational culture at the policing
Applied Studies in Agribusiness and Commerce, 2014 The subject of this thesis is presentation of the examination related to the organizational culture of the Police, the special law enforcement body which guarantees internal order and public security. The police, at the same time, as armed law enforcement body ensure the order of the economy and its legal security.
openaire +3 more sources
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Rāhburdhā-yi Mudīriyyat dar Niẓām-i Salāmat, 2017 Background: The operation of an organization can be improved by organizational culture and commitment. Further, culture is one of the most basic tools for development of entrepreneurial.
Razieh Montazeralfaraj +2 more
doaj
İlköğretim Online, 2021 Culture of the workplace is very powerful force, which is consciously and deliberately cultivated and is passed on to the new generation of the employees. Organizations build up their culture for the survival in the market, and for achieving growth under competitive conditions. There are different patterns of culture.
Dr. Shalaka Sakhrekar +3 more
openaire +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Adaptations of a Global Organizational Culture in China, the UK and the US: Does Social Culture Make Any Difference? [PDF]
, 2010 [[abstract]]This research examined the extent to which organizational subunits of a single organization adapted the organizational culture to different social cultural contexts, and the implications of such adaptations on individual level outcomes ...
CATHERINE T. KWANTES +2 more
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