Results 91 to 100 of about 4,842,709 (257)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Further examination of the organizational culture scale of artifacts [PDF]

open access: yes
The construct validity of a 10-item Organizational Culture Scale Focused on Artifacts oriented to measure traditional culture was analyzed under the unidimensionality hypothesis of the scale.
Molina, Gabriel   +2 more
core  

Breaking the Silence: The role of gossip in organizational culture [PDF]

open access: yes, 2011
From the early 1980s, the number of studies pertaining to organizational culture expanded considerably to the point where it could reasonably be argued that the field had reached a level of maturity.
Michelson, G.   +2 more
core  

Research in Organizational Culture [PDF]

open access: yesمطالعات مدیریت بهبود و تحول, 2004
فرهنگ سازمانی یکی از موضوعات مورد علاقه نویسندگان و پژوهشگران رشته مدیریت در دهه های اخیر بوده است. پژوهش های زیادی در این زمینه انجام شده و مقالات و کتب متعددی به رشته تحریر در آمده اند که از گونه گونی بسیار در مبانی نظری، اهداف و روش ها برخوردار می ...
seyed mohammad zahedi
doaj  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Organizational Culture and Relationship Skills [PDF]

open access: yes
While both the strategic management and the network literature recognize the importance of inter-firm relationships for explaining competitive advantage, the question why firms differ in their ability to benefit from these relationships is rarely ...
Noorderhaven, N.G.   +2 more
core  

Developing the Organizational Culture [PDF]

open access: yesRevista de Management Comparat International, 2015
In the new economy, organizations face a number of challenges that leaders will have to find answers to and for which the knowledge-based leadership can be an important part of the solutions that are identified.
Geantă SERGIU
doaj  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

The typology of Organizational Culture of Shahid Chamran University of Ahvaz and its effect on Employees' Organizational Health

open access: yesمشاوره شغلی و سازمانی, 2019
The aim of this study is evaluation and typology the organizational culture and its impact on Employees' organizational health. The statistical population of this research is all employees of Shahid Chamran University of Ahvaz, Because of the great and ...
سارا محمدی
doaj  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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