Results 121 to 130 of about 783,880 (299)

Systems engineering and integration and management for manned space flight programs [PDF]

open access: yes
This paper discusses the history of SE&I management of the overall program architecture, organizational structure and the relationship of SE&I to other program organizational elements.
Morris, Owen
core   +1 more source

The Hidden Side of Transparency among Government Agency Bloggers [PDF]

open access: yes, 2012
This paper shows and discusses blogs as social action in a corporate context by investigating and seeking to understand organizational bloggers’ motivations and discursive behaviors in the contextual and cultural diversity of a\ud blog-setting. Providing
Agerdal-Hjermind, Annette
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Individual Entrepreneurship Capacity and Performance of SMEs [PDF]

open access: yes
This paper analyses the importance of human capital and organizational capital on the determination of SME’s performance, by proposing and testing a conceptual model about Individual Entrepreneurship Capacity, and its impact both on non-economic and ...
Franco, Mário, Leitão, João
core   +1 more source

What Matters to Whom? Managing Trust Across Multiple Stakeholder Groups [PDF]

open access: yes, 2007
Trust has been widely recognized as a key enabler of organizational success. Prior research on organizational trust, however, has not distinguished between the potentially varying bases of trust across different stakeholder groups (e.g., employees ...
Deepak Malhotra, Michael Pirson
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

The mediating role of organizational identification in the effect of compulsory citizenship behavior on employee silence: The case of Turkish (Konya province) manufacturing industry

open access: yesEkonomski Vjesnik
Purpose: This study discusses the concept of compulsory citizenship behavior (CCB) and identifies the relationships between CCB, organizational identification, and employee silence bearing in mind the Conservation of Resources Theory (COR).
Abdullah Sami Ergül, Gökhan Kerse
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

A humanistic approach to organizations and to organizational decision-making [PDF]

open access: yes
This paper attempts to take steps towards the formulation of a more human approach to the theory of the firm than the conventional economics-based models.
Rosanas, Josep M.
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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