Results 41 to 50 of about 23,786 (248)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

DO ORGANIZATIONAL JUSTICE PERCEPTIONS INFLUENCE HEALTHCARE WORKERS' ORGANIZATIONAL CITIZENSHIP BEHAVIOR?

open access: yesInternational Journal of Health Services Research and Policy, 2017
Employees in complex and chaotic hospitals have become important for the perception of organizational justice to see themselves as a citizen of the institution.
Sedat Bostan, Taşkın KILIÇ
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

The Role of Perceived Organizational Justice in Job Procrastination [PDF]

open access: yesجامعه شناسی کاربردی, 2017
Introduction   This study aims to describe, predict and explain job procrastination through the variable of organizational justice. Numerous factors affect job procrastination, some of which are personal.
Abbas Khakpour, Mitra Gholipour
doaj   +1 more source

Effects of Organizational Support and Organizational Justice on Police Officers’ Work Engagement

open access: yesFrontiers in Psychology, 2021
The impact of organizational support and organizational justice on work engagement was investigated in a group of police officers. A review of the literature revealed that studies reporting differences between the influence of supervisors and coworker ...
Andrzej Piotrowski, Samir Rawat, Ole Boe
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

The Impact of Perceived Organizational Justice on ‎Organizational Commitment among Bouchrit Corporation ‎Employees

open access: yesدراسات العدد الاقتصادي, 2015
The purpose of this study is to examine the influence of perceived organizational justice on organizational commitment among a sample of employees within Bouchrit Corporation. Using a self-administered questionnaire, 31 employees, were randomly selected
Abouelkacem ‎ HAMDI
doaj   +1 more source

Organizational Justice: Typology, Antecedents and Consequences

open access: yesEncyclopedia, 2022
Organizational Justice is an individual’s perception that events, actions, or decisions within an organization adhere to a standard of fairness. Justice researchers have categorized justice into four types, differentiated by how fairness is evaluated by ...
Jennifer Wiseman, Amelia Stillwell
doaj   +1 more source

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