Results 41 to 50 of about 7,272,980 (293)

Job crafting interventions: what works, for whom, why, and in which contexts? Research protocol for a systematic review with coincidence analysis

Systematic Reviews, 2023
Background Recent challenges in the working world that resulted from the pandemic and technological advances have underlined the importance of flexibility in how jobs are designed.
Marta Roczniewska, Anna Rogala, Magdalena Marszałek, Henna Hasson, Arnold B. Bakker, Ulrica von Thiele Schwarz   +5 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Comparative Analysis of Social Responsibility Model Implementation in Civil Society and Corporate Sector Organizations in Serbia

Management
Research Question: To what extent is social responsibility model applied within civil society and corporate sector organizations in the Republic of Serbia?
Jovana Dimitrijević, Mladen Đurić, Jelena V. Pokimica   +2 more
doaj   +1 more source

Building Organizational Resilience Through Organizational Learning: A Systematic Review

Frontiers in Communication, 2022
With organizational environments becoming increasingly complex and volatile, the concept of “organizational resilience” has become the “new normal”.
Lise L. Evenseth, Maria Sydnes, Anne H. Gausdal   +2 more
doaj   +1 more source

Organizational Learning Oriented Model of Organizational Adaptation [PDF]

, 2005
This paper proposes an agent-based simulation model for analyzing adaptive processes of organizations with organizational learning. The model is based on a framework of organizational cybernetics and represents organizational activities both decision ...
Takahashi, Shingo, Goto, Yusuke
core  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The relationship between slack resources and organizational resilience: The moderating role of dual learning

Heliyon, 2023
Slack resources and organizational learning are key elements in building organizational resilience. This paper constructs an impact model of organizational resilience and investigates the impact of slack resources on organizational resilience using data ...
Yafei Mao, Peisi Li, Yi Li
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source