Results 21 to 30 of about 5,282 (198)
Nature Communications, 2022 The combination of transition metal catalysis and organocatalysis can afford both good reactivity and selectivity. Here, the authors present an α − propargylation of N-unprotected amino acid esters with propargylic alcohol derivatives via dual nickel and
Fang Zhu +5 more
doaj +1 more source
Building Molecules by a Self‐Replicator That Catalyzes Acyl Hydrazone Formation
Angewandte Chemie, EarlyView.A self‐replicator efficiently catalyzes the formation of acyl hydrazone bonds between a set of different substrates. In addition to previously reported (bond‐breaking) catalytic activity, this renders the self‐replicator highly promiscuous, which is a good starting point for Darwinian experiments en route to de‐novo life.
Kayleigh S. van Esterik +2 more
wiley +2 more sources
Magnetic nanoparticle-supported organocatalysis
Green Processing and Synthesis, 2013 Magnetic nanoparticle (MNP)-supported catalysis is a new method to facilitate catalyst separation and reuse. This technique has recently been introduced for organocatalysis.
Huang Yibo, Zhang Wei
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One-Pot Synthesis of Dioxime Oxalates
Molbank, 2022 Dioxime oxalates, a type of carbonyl oximes, are well-known as clean sources of iminyl radicals that undergo key organic chemistry transformations. A series of dioxime oxalates is reported in this manuscript, obtained by the reaction of the corresponding
Laura Adarve-Cardona +3 more
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Enantiospecific Optical Sensing of Terpenes by an Aggregated Atropisomeric Platinum(II) Complex
Angewandte Chemie, EarlyView.Aggregated metal complexes act as an artificial nose and permit reversible optical sensing of small volatile molecules like R/S‐limonene based on enantiospecific recognition. Abstract Terpenes are unfunctionalized small volatile organic compounds (VOCs) that are naturally abundant, relevant to climate change, and impose potential health risks.
Annika Huber +3 more
wiley +2 more sources
Desymmetrization of N-Cbz glutarimides through N-heterocyclic carbene organocatalysis
Nature Communications, 2022 Desymmetrization of achiral building blocks is one of the most efficient ways to access enantiopure compounds of synthetic relevance. Here, the authors desymmetrize glutarimides with alcohols via an imide C–N bond cleavage under NHC organocatalysis.
Zhouli Hu +12 more
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Asymmetric organocatalysis involving double activation
Tetrahedron Chem, 2022 Asymmetric organocatalysis contributed tremendously to the field of organic synthesis since year 2000. Considering the diversity of organocatalysts and their activation modes, chemists developed the double activation strategy, in which two distinct ...
Zhi Chen +3 more
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Non-Covalent Organocatalyzed Domino Reactions Involving Oxindoles: Recent Advances
Molecules, 2017 The ubiquitous presence of spirooxindole architectures with several functionalities and stereogenic centers in bioactive molecules has been appealing for the development of novel methodologies seeking their preparation in high yields and selectivities ...
Tecla Gasperi +3 more
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Molecules, 2019 Chirality is one of the most important attributes for its presence in a vast majority of bioactive natural products and pharmaceuticals. Asymmetric organocatalysis methods have emerged as a powerful methodology for the construction of highly ...
Zhonglei Wang
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Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists
Molecules, 2022 Majority of drugs act by interacting with chiral counterparts, e.g., proteins, and we are, unfortunately, well-aware of how chirality can negatively impact the outcome of a therapeutic regime.
Efraim Reyes +2 more
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