Results 71 to 80 of about 106,655 (301)

The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future. [PDF]

, 2020
The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex multi-cellular organ that intimately links with the cardiovascular system to accomplish gas exchange.
Basil, Maria C, Chapman, Hal A, Engler, Anna E, Guo, Minzhe, Herriges, Michael J, Kathiriya, Jaymin J, Katzen, Jeremy, Kotton, Darrell N, Morrisey, Edward E, Rock, Jason R, Snoeck, Hans-Willem, Vunjak-Novakovic, Gordana, Whitsett, Jeffrey A, Windmueller, Rebecca, Ysasi, Alexandra B, Zacharias, William J   +15 more
core   +2 more sources

Organoid nevus phakomatosis

Acta Dermato-Venereologica, 1980
Abstract is not ...
K, Kuokkanen, M, Koivikko, M, Alavaikko
openaire   +2 more sources

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

Advanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam, Seon Yeong Chae, Young Woo Kwon, Hye Jin Heo, Hye Rin Lee, Ji Hyeok Lee, Dong‐Wook Han, Yun Hak Kim, Suck Won Hong   +8 more
wiley   +1 more source

Synergistic Overexpression of Sox9, TGFβ1, and Col II Induces Functional Chondrogenesis in hUC-MSCs Using a 3D Culture Approach

Organoids
Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) possess the potential for chondrogenic differentiation, offering a promising alternative source for cartilage regeneration.
Shumaila Khalid, Sobia Ekram, Faiza Ramzan, Asmat Salim, Irfan Khan   +4 more
doaj   +1 more source

Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis. [PDF]

, 2020
Copper levels are known to be elevated in inflamed and malignant tissues. But the mechanism underlying this selective enrichment has been elusive. In this study, we report a axis by which inflammatory cytokines, such as IL-17, drive cellular copper ...
Bao, Shideng, Bulek, Katarzyna, Cai, Gang, Chang, Christopher J, Chen, Xing, Fox, Paul L, Huang, Emina, Jackson, Mark W, Jia, Shang, Kalady, Matthew F, Li, Xiaoxia, Liao, Yun, Pizarro, Theresa T, Sen, Ganes C, Stark, George R, Tang, Fangqiang, Zhao, Junjie   +16 more
core  

Epithelial cell specific Raptor is required for initiation of type 2 mucosal immunity in small intestine [PDF]

, 2017
Intestinal tuft cells are one of 4 secretory cell linages in the small intestine and the source of IL-25, a critical initiator of the type 2 immune response to parasite infection. When Raptor, a critical scaffold protein for mammalian target of rapamycin
Aladegbami, Bola, Bao, James, Barron, Lauren, Colasanti, Jason, Erwin, Christopher R, Guo, Jun, Warner, Brad W   +6 more
core   +2 more sources

Nanodiamond Quantum Sensors for Probing Free Radical Biology

Advanced Functional Materials, EarlyView.
Free radicals play key roles in cellular signaling and disease but remain difficult to measure in living systems. Nanodiamonds (NDs) with nitrogen‐vacancy (NV) centers enable quantum sensing of local magnetic noise via T₁ relaxometry, providing nondestructive radical detection in living cells.
Qi Lu, Yingke Wu, Tanja Weil
wiley   +1 more source

Organoid Models: Revolutionizing Disease Modeling and Personalized Therapeutics

Organoids
As a three-dimensional in vitro model, organoid technology represents a revolutionary breakthrough in precision medicine. By harnessing the self-organizing capabilities of stem cells within biomimetic extracellular matrices, it enables the generation of ...
Zhifeng Xue, Runze Yang, Yaling Liu, Han Luo   +3 more
doaj   +1 more source

Human in vitro models for understanding mechanisms of autism spectrum disorder. [PDF]

, 2020
Early brain development is a critical epoch for the development of autism spectrum disorder (ASD). In vivo animal models have, until recently, been the principal tool used to study early brain development and the changes occurring in neurodevelopmental ...
Geschwind, Daniel H, Gordon, Aaron
core  

Targeting the tumor microenvironment in colorectal peritoneal metastases

, 2020
Peritoneal metastasis (PM) occurs in approximately one in four colorectal cancer (CRC) patients. The pathophysiology of colorectal PM remains poorly characterized. Also, the efficacy of current treatment modalities, including surgery and intraperitoneal (
Ceelen, Wim, De Wever, Olivier, Heriot, Alexander G., Narasimhan, Vignesh, Ramsay, Robert G.   +4 more
core   +1 more source