Results 31 to 40 of about 7,059 (201)
Molecules, 2015 α-Linolenic acid (ALA) is a nutraceutical found in vegetable products such as flax and walnuts. The pleiotropic properties of ALA target endogenous neuroprotective and neurorestorative pathways in brain and involve the transcription factor nuclear factor
Tetsade Piermartiri +3 more
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Optimization of the Ocular Treatment Following Organophosphate Nerve Agent Insult [PDF]
Toxicological Sciences, 2017 Eye exposure to organophosphate (OP) irreversible acetylcholinesterase inhibitors, results in long-term miosis and impaired visual function. The aim of this study was to find an anticholinergic antidote, which would counteract miosis and visual impairment induced by the nerve agents sarin and VX with minimal untoward side-effects.
Inbal, Egoz +3 more
openaire +2 more sources
, 2014 Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust +15 more
core +2 more sources
Sensors, 2009 A cholinesterase based biosensor was constructed in order to assess the effects of ionizing radiation on exposed AChE. Although the primary objective of the experiment was to investigate the effect of ionizing radiation on the activity of the biosensor ...
Miroslav Pohanka, Miroslav Koch
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PNPLA6/NTE, an Evolutionary Conserved Phospholipase Linked to a Group of Complex Human Diseases
Metabolites, 2022 Patatin-like phospholipase domain-containing protein 6 (PNPLA6), originally called Neuropathy Target Esterase (NTE), belongs to a family of hydrolases with at least eight members in mammals.
Doris Kretzschmar
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Epigenetic analysis in a murine genetic model of Gulf War illness
Frontiers in Toxicology, 2023 Of the nearly 1 million military personnel who participated in the 1990–1991 Gulf War, between 25% and 35% became ill with what now is referred to as Gulf War Illness (GWI) by the Department of Defense.
Khyobeni Mozhui +8 more
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Gulf War Syndrome: A role for organophosphate induced plasticity of locus coeruleus neurons [PDF]
, 2011 Gulf War syndrome is a chronic multi-symptom illness that has affected about a quarter of the deployed veterans of the 1991 Gulf War. Exposure to prolonged low-level organophosphate insecticides and other toxic chemicals is now thought to be responsible.
Andrew L. Varnell +2 more
core +3 more sources
Nanomaterials, 2021 Organophosphate (OP) compounds, a family of highly hazardous chemical compounds included in nerve agents and pesticides, have been linked to more than 250,000 annual deaths connected to various chronic diseases. However, a solid-state sensing system that
A K M Mashud Alam +3 more
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Chronic behavioral and cognitive deficits in a rat survival model of paraoxon toxicity [PDF]
, 2014 Organophosphate (OP) compounds, including paraoxon (POX), are similar to nerve agents such as sarin. There is a growing concern that OP agents could be weaponized to cause mass civilian causalities.
DeLorenzo, Robert J. +3 more
core +2 more sources
Sensors, 2013 The enzyme acetylcholinesterase (AChE) is an important part of cholinergic nervous system, where it stops neurotransmission by hydrolysis of the neurotransmitter acetylcholine.
Rene Kizek +2 more
doaj +1 more source