Results 11 to 20 of about 7,059 (201)
Electrochemical stripping analysis of organophosphate pesticides and nerve agents
Electrochemistry Communications, 2005 Abstract A sensitive electrochemical stripping voltammetric method for analyzing organophosphate (OP) compounds was developed using a carbon paste electrochemical (CPE) transducer. OPs strongly adsorb on a CPE surface and provide facile electrochemical quantitative methods for electroactive OP compounds.
Guodong Liu, Yuehe Lin
openaire +3 more sources
The role of oxidative stress in organophosphate and nerve agent toxicity [PDF]
Annals of the New York Academy of Sciences, 2016 Organophosphate (OP) nerve agents exert their toxicity through inhibition of acetylcholinesterase. The excessive stimulation of cholinergic receptors rapidly causes neuronal damage, seizures, death, and long‐term neurological impairment in those that survive.
Jennifer N, Pearson, Manisha, Patel
openaire +4 more sources
Chemical Properties, Biological Activities and Poisoning Treatment of Novichok: A Review
Pharmaceutical Sciences and Research, 2021 Novichok is an organophosphate compound found as a nerve agent chemical weapon. However, the information about its chemical properties, biological activities, and molecular interactions in the body are still protected under the “top secret” security ...
Tesia Aisyah Rahmania +3 more
doaj +1 more source
Neurobiology of Disease, 2020 A novel oxime platform, the substituted phenoxyalkyl pyridinium oximes (US patent 9,227,937), was invented at Mississippi State University with an objective of discovering a brain-penetrating antidote to highly potent organophosphate anticholinesterases,
Janice E. Chambers, Edward C. Meek
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Rapid Non-Contact Detection of Chemical Warfare Agents by Laser Photoacoustic Spectroscopy
Sensors, 2023 Nerve agents have recently been used in battlefield operations, espionage wars, and terrorist attacks. These compounds, like some pesticides, cause organophosphate poisoning.
Luca Fiorani +3 more
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Tuning Butyrylcholinesterase Inactivation and Reactivation by Polymer‐Based Protein Engineering
Advanced Science, 2020 Organophosphate nerve agents rapidly inhibit cholinesterases thereby destroying the ability to sustain life. Strong nucleophiles, such as oximes, have been used as therapeutic reactivators of cholinesterase‐organophosphate complexes, but suffer from ...
Libin Zhang +7 more
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Erratum: Isoflurane-lipid emulsion injection as an anticonvulsant and neuroprotectant treatment for nerve agent exposure [PDF]
Frontiers in PharmacologyFrontiers Production Office
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Epilepsia Open, 2020 Objective Organophosphates (OPs) such as diisopropylfluorophosphate (DFP) and soman are lethal chemical agents that can produce seizures, refractory status epilepticus (SE), and brain damage.
Doodipala Samba Reddy +5 more
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Role of the Calcium Plateau in the Neuronal Injury and Behavioral Morbidities Following Organophosphate Intoxication [PDF]
, 2016 Organophosphate (OP) chemicals include nerve agents and pesticides, and there is a growing concern of OP based chemical attacks against civilians. Current antidotes are essential in limiting immediate mortality associated with OP exposure.
Battaglia F.P. +8 more
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Scientific Reports, 2021 Toxicity of organophosphorus compounds (OPs) remains a major public health concern due to their widespread use as pesticides and the existence of nerve agents.
Tena Čadež +3 more
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