Results 41 to 50 of about 7,059 (201)

Recovery of Cerium Dioxide from Spent Glass-Polishing Slurry and Its Utilization as a Reactive Sorbent for Fast Degradation of Toxic Organophosphates

open access: yesAdvances in Materials Science and Engineering, 2015
The recovery of cerium (and possibly other rare earth elements) from the spent glass-polishing slurries is rather difficult because of a high resistance of polishing-grade cerium oxide toward common digestion agents.
Pavel Janoš   +8 more
doaj   +1 more source

Brief isoflurane administration as an adjunct treatment to control organophosphate-induced convulsions and neuropathology

open access: yesFrontiers in Pharmacology, 2023
Organophosphate-based chemical agents (OP), including nerve agents and certain pesticides such as paraoxon, are potent acetylcholinesterase inhibitors that cause severe convulsions and seizures, leading to permanent central nervous system (CNS) damage if
Narayanan Puthillathu   +9 more
doaj   +1 more source

Novel therapeutics for treating organophosphate-induced status epilepticus co-morbidities, based on changes in calcium homeostasis

open access: yesNeurobiology of Disease, 2020
Organophosphate (OP) chemicals include pesticides such as parathion, and nerve gases such as sarin and soman and are considered major chemical threat agents. Acute OP exposure is associated with a cholinergic crisis and status epilepticus (SE).
Laxmikant S. Deshpande   +1 more
doaj   +1 more source

Backbone Conformation Shifts in X-ray Structures of Human Acetylcholinesterase upon Covalent Organophosphate Inhibition

open access: yesCrystals, 2021
Conformations of Cα backbones in X-ray structures of most organophosphate (OP)-inhibited human acetylcholinesterases (hAChEs) have been previously shown to be similar to that of the native hAChE.
Stephanie Luedtke   +5 more
doaj   +1 more source

Transient Expression of Tetrameric Recombinant Human Butyrylcholinesterase in Nicotiana benthamiana. [PDF]

open access: yes, 2016
To optimize the expression, extraction and purification of plant-derived tetrameric recombinant human butyrylcholinesterase (prBChE), we describe the development and use of plant viral amplicon-based gene expression system; Tobacco Mosaic Virus (TMV) RNA-
Alkanaimsh, Salem   +13 more
core   +1 more source

Neuropharmacology: Oxime antidotes for organophosphate pesticide and nerve agent poisoning

open access: yesPeriodicum Biologorum, 2020
Organophosphate (OP) compounds remain a great threat for humans because they are used as pesticides or misused as chemical warfare nerve agents. Their mechanism of toxicity involves the irreversible inhibition of the acetylcholinesterase (AChE) enzyme important in the control of cholinergic neurotransmission at the periphery and in the brain.
Zorbaz, Tamara, Kovarik, Zrinka
openaire   +4 more sources

Complex View on Poisoning with Nerve Agents and Organophosphates [PDF]

open access: yesActa Medica (Hradec Kralove, Czech Republic), 2005
OP/nerve agents are still considered as important chemicals acting on living organisms and widely used in human practice. Nerve agents are the most lethal chemical warfare agents. They are characterized according to their action as compounds influencing cholinergic nerve transmission via inhibition of AChE.
openaire   +3 more sources

Distal symmetrical polyneuropathy due to organophosphate intoxication

open access: yesMedicine Science, 2017
While a cholinergic crisis picture is onset in intoxication of organophosphate compounds; a severe polyneuropathy mainly affecting the motor fibers is viewed lately following weeks.
Semih Alay   +4 more
doaj   +1 more source

Effects of Surface and Morphological Properties of Zeolite on Impedance Spectroscopy-Based Sensing Performance

open access: yesSensors, 2012
Measurement by impedance spectroscopy of the changes in intrazeolitic cation motion of pressed pellets of zeolite particles upon adsorption of dimethylmethylphosphonate (DMMP) provides a strategy for sensing DMMP, a commonly used simulant for highly ...
Prabir K. Dutta   +3 more
doaj   +1 more source

Repeated low-dose organophosphate DFP exposure leads to the development of depression and cognitive impairment in a rat model of Gulf War Illness [PDF]

open access: yes, 2016
Approximately 175,000 to 250,000 of the returning veterans from the 1991 Persian Gulf War exhibit chronic multi-symptom illnesses that includes neurologic co-morbidities such as depression, anxiety and cognitive impairments.
Deshpande, Laxmikant, Phillips, Kristin
core   +2 more sources

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