Results 101 to 110 of about 7,205 (295)

Analysis of oriC-dependent growth rate regulation through genetic targeting of essential cellular activities.

open access: yes, 2014
Strains were grown overnight at 37°C in LB medium; strains harbouring plasmids integrated into the genome by single-crossover were supplemented with appropriate antibiotics and inducer (0.1 mM IPTG or 0.1% xylose).
Alan Koh (650230), Heath Murray (650229)
core   +1 more source

Transcriptional Regulation Buffers Gene Dosage Effects on a Highly Expressed Operon in Salmonella

open access: yesmBio, 2018
Highly expressed genes are commonly located close to the origin of replication of bacterial chromosomes (OriC). This location skew is thought to reflect selective advantages associated with gene dosage effects during the replication cycle. The expression
Eva Garmendia   +2 more
doaj   +1 more source

A novel small molecule inhibitor of CD73 triggers immune-mediated multiple myeloma cell death

open access: yesBlood Cancer Journal
Highlights CD73 is the key ectoenzyme involved in the generation of AMP-derived adenosine, which contributes to immunosuppression in the MM BM milieu. Blocking CD73 activity with a potent, selective, orally bioavailable CD73 inhibitor ORIC-533 decreases ...
Arghya Ray   +19 more
doaj   +1 more source

Role, Importance of ORIC and Entrepreneurship in Universities

open access: yesPakistan Journal of Medicine and Dentistry, 2020
The entrepreneurial universities aim to facilitate practical knowledge to students and industries to foster economic development. Many ideas were put forward to pioneer universities in the United States like Massachusetts Institute of Technology (MIT) and Stanford, and establish a solid patent policy, technology transfer policy and Liaison between ...
openaire   +2 more sources

The Escherichia coli cryptic prophage protein YfdR binds to DnaA and initiation of chromosomal replication is inhibited by overexpression of the gene cluster yfdQ-yfdR-yfdS-yfdT

open access: yesFrontiers in Microbiology, 2016
The initiation of bacterial chromosomal replication is regulated by multiple pathways. To explore novel regulators, we isolated multicopy suppressors for the cold-sensitive hda-185 ΔsfiA(sulA) mutant.
Yaunori eNoguchi, Tsutomu eKatayama
doaj   +1 more source

Relative positions of repeats with respect to oriC

open access: yes, 2022
zipped folder containing 5970 files (genomes with at least 30 distinct positions with repeats). Each file represents one genome with the filename as its GCF ID (NCBI accession id).
Aswin Sai Narain Seshasayee (12018376)   +1 more
core   +1 more source

The Effect of Sintering Flue Gas Composition on NO Reduction in Coke

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The strategy of substituting combustion air with sintering flue gas in circulating fluidized bed (CFB) systems provides a low‐cost and highly efficient approach for the purification of sintering off‐gas. In this work, coke was employed as the reducing agent, and a high‐temperature vertical tube furnace was used to simulate the dense‐phase ...
Canbin Huang   +5 more
wiley   +1 more source

E. coli SeqA protein binds oriC in two different methyl-modulated reactions appropriate to its roles in DNA replication initiation and origin sequestration

open access: yes, 1995
The segA gene negatively modulates replication initiation at the E. coil origin, oriC. segA is also essential for sequestration, which acts at oriC and the dnaA promoter to ensure that replication initiation occurs exactly once per chromosome per cell ...
Kleckner, Nancy   +5 more
core   +1 more source

MicroCT reinvestigation of the only articulated fossil anostomid fish reveals synonymy of Arhinolemur Ameghino, 1898 and Megaleporinus Ramirez et al., 2017

open access: yesThe Anatomical Record, EarlyView.
Abstract Arhinolemur scalabrinii† Ameghino, 1898 was originally described as a strepsirrhine primate (Mammalia) but has been recognized as an anostomid fish since 2012. It remains the only extinct anostomid species known from complete cranial material.
Karen M. Panzeri   +8 more
wiley   +1 more source

Organizational readiness for change towards implementing a sepsis survivor hospital to home transition-in-care protocol

open access: yesFrontiers in Health Services
BackgroundOrganizational readiness for change, defined as the collective preparedness of organization members to enact changes, remains understudied in implementing sepsis survivor transition-in-care protocols.
Elaine Sang   +27 more
doaj   +1 more source

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