Results 101 to 110 of about 7,859 (293)

Control regions for chromosome replication are conserved with respect to both sequence and location between Escherichia coli strains

open access: yesFrontiers in Microbiology, 2015
In Escherichia coli, chromosome replication is initiated from oriC by the DnaA initiator protein associated with ATP. Three non-coding regions contribute to the activity of DnaA.
Jakob eFrimodt-Møller   +3 more
doaj   +1 more source

Sulfide‐Based Electrolytes for All‐Solid‐State Sodium Batteries

open access: yesAdvanced Energy Materials, EarlyView.
This review covers the structural features and synthesis strategies of sulfide‐based solid electrolytes, as well as critical challenges related to conductivity, interfacial and moisture stability, and scaling‐up for practical application in Sodium‐based All Solid‐State Batteries.
Han Yang   +6 more
wiley   +1 more source

A novel small molecule inhibitor of CD73 triggers immune-mediated multiple myeloma cell death

open access: yesBlood Cancer Journal
Highlights CD73 is the key ectoenzyme involved in the generation of AMP-derived adenosine, which contributes to immunosuppression in the MM BM milieu. Blocking CD73 activity with a potent, selective, orally bioavailable CD73 inhibitor ORIC-533 decreases ...
Arghya Ray   +19 more
doaj   +1 more source

Cooperation between two modes for DNA replication initiation in the archaeon Thermococcus barophilus

open access: yesmBio
The mechanisms underpinning the replication of genomic DNA have recently been challenged in Archaea. Indeed, the lack of origin of replication has no deleterious effect on growth, suggesting that replication initiation relies on homologous recombination.
Logan Mc Teer   +13 more
doaj   +1 more source

The Stringent Response Inhibits DNA Replication Initiation in E. coli by Modulating Supercoiling of oriC

open access: yesmBio, 2019
The stringent response enables bacteria to respond to a variety of environmental stresses, especially various forms of nutrient limitation. During the stringent response, the cell produces large quantities of the nucleotide alarmone ppGpp, which ...
James A. Kraemer   +2 more
doaj   +1 more source

Analysis of oriC-dependent growth rate regulation through genetic targeting of essential cellular activities.

open access: yes, 2014
Strains were grown overnight at 37°C in LB medium; strains harbouring plasmids integrated into the genome by single-crossover were supplemented with appropriate antibiotics and inducer (0.1 mM IPTG or 0.1% xylose).
Alan Koh (650230), Heath Murray (650229)
core   +1 more source

Comparative Insights and Overlooked Factors of Interphase Chemistry in Alkali Metal‐Ion Batteries

open access: yesAdvanced Energy Materials, EarlyView.
This review presents a comparative analysis of Li‐, Na‐, and K‐ion batteries, focusing on the critical role of electrode–electrolyte interphases. It especially highlights overlooked aspects such as SEI/CEI misconceptions, binder effects, and self‐discharge relevance, emphasizing the limitations of current understanding and offering strategies for ...
Changhee Lee   +3 more
wiley   +1 more source

Transcriptional Regulation Buffers Gene Dosage Effects on a Highly Expressed Operon in Salmonella

open access: yesmBio, 2018
Highly expressed genes are commonly located close to the origin of replication of bacterial chromosomes (OriC). This location skew is thought to reflect selective advantages associated with gene dosage effects during the replication cycle. The expression
Eva Garmendia   +2 more
doaj   +1 more source

Role, Importance of ORIC and Entrepreneurship in Universities

open access: yesPakistan Journal of Medicine and Dentistry, 2020
The entrepreneurial universities aim to facilitate practical knowledge to students and industries to foster economic development. Many ideas were put forward to pioneer universities in the United States like Massachusetts Institute of Technology (MIT) and Stanford, and establish a solid patent policy, technology transfer policy and Liaison between ...
openaire   +2 more sources

Oric Central Region Calculations [PDF]

open access: yes, 1995
The central region for the K = 100 Oak Ridge Isochronous Cyclotron, ORIC, will be modified to provide better orbit centering, focusing of orbits in the axial direction, and phase selection, in order to improve extraction efficiency, and reduce ...
Dowling, D. T.   +5 more
core  

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