Results 171 to 180 of about 7,859 (293)

Changes in effectiveness and safety in patients with Lennox–Gastaut syndrome transitioning from the fenfluramine randomized controlled trial to open‐label extension study

Epilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis describing the trajectories of fenfluramine effectiveness and safety, along with dose changes over time, in patients with Lennox‐Gastaut syndrome. Abstract In the phase 3 randomized controlled trial (RCT; NCT03355209) of fenfluramine in Lennox–Gastaut syndrome (LGS),
Rima Nabbout, Orrin Devinsky, Lieven Lagae, Ingrid E. Scheffer, Renzo Guerrini, Joseph Sullivan, Antonio Gil‐Nagel, Sameer M. Zuberi, Kate Riney, Patrick Healy, Jayne Abraham, Rebecca Zhang Roper, Mélanie Langlois, Amélie Lothe, Kelly G. Knupp   +14 more
wiley   +1 more source

The chromosomal origin of replication as the basis for the spatio-temporal biology of bacteria. [PDF]

Front Microbiol
Norris V, Herrick J, Kohiyama M.
europepmc   +1 more source

Glucocorticoid Receptor Antagonist ORIC-101 [PDF]

, 2020
openaire   +1 more source

Magnetic field measuring system for remapping the ORIC magnetic field

, 1977
The Holifield Heavy Ion Research Facility will integrate a new 25 MV tandem electrostatic acccelerator into the existing cyclotron laboratory which includes the Oak Ridge Isochronous Cyclotron (ORIC). Computations of ion paths for beam injection from the
Hensley, D. C., Mosko, S. W., Lord, R. S., Biggerstaff, J. A., Hudson, E. D.   +4 more
core  

Efficacy and safety of fenfluramine in Dravet syndrome: The impact of patient clinical characteristics

Epilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis evaluating the efficacy and safety of fenfluramine in patients with Dravet syndrome stratified by age, number of previously attempted antiseizure medications, and SCN1A pathogenic variant status using data pooled from the three pivotal randomized controlled trials ...
Rima Nabbout, Joseph Sullivan, Stéphane Auvin, J. Helen Cross, Orrin Devinsky, Antonio Gil‐Nagel, Renzo Guerrini, Kelly G. Knupp, M. Scott Perry, Rocío Sánchez‐Carpintero, An‐Sofie Schoonjans, Ingrid E. Scheffer, Nicola Specchio, Adam Strzelczyk, James Wheless, Elaine C. Wirrell, Diego Morita, Patrick Healy, Mélanie Langlois, Amélie Lothe, Lieven Lagae   +20 more
wiley   +1 more source

Correction: Dual-functional Ni and Co oxide-doped carbon nanocomposite: an effective catalyst for electrochemical water splitting and CO₂ utilization. [PDF]

RSC Adv
Zia M, Ahmad Z, Munawar KS, Khattak ZAK, Raza H, Idrees H, Younus HA, Shaheen MA, Ahmad N.   +8 more
europepmc   +1 more source

DECREASE study: A European pool‐analysis of patients with significant reductions in concomitant antiseizure medications in cenobamate Early Access Programs

Epilepsia Open, EarlyView.
Abstract Objective To evaluate the effectiveness and tolerability of cenobamate in patients with a significant reduction in concomitant antiseizure medication (ASM) in European cenobamate Early Access Programs (EAPs). Method Anonymized patient data from real‐world studies/registries associated with European cenobamate EAPs were pooled.
Vicente Villanueva, Simona Lattanzi, Javier Peña‐Ceballos, Rhys H. Thomas, Juan Rodríguez‐Uranga, Zsófia Jordán, Bernhard J. Steinhoff, Randi von Wrede, Norman Delanty, Patrick B. Moloney, Roberta Roberti, Giovanni Boero, Laura Canafoglia, Nicola Specchio, Antonio Gambardella, Edoardo Ferlazzo, Francesca Felicia Operto, Elena Tartara, Hester Garratt, Dániel Fabó, Asier Gómez‐Ibáñez, Gustavo Torres‐Gaona, Yulia Novitskaya, Rainer Surges, Kevin Hampel, Andreas Schulze‐Bonhage   +25 more
wiley   +1 more source

A self-replicating artificial module-genome that generates bacterial chromosome replication system in vitro. [PDF]

Nucleic Acids Res
Yamagishi Y, Sonoyama Y, Kawakami N, Hasebe T, Su'etsugu M.   +4 more
europepmc   +1 more source

Catalytic Pyrolysis of Torrefied Municipal Solid Waste Using Local Iron for Improved Bio‐Oil Yield and Energy Efficiency

Energy Science &Engineering, EarlyView.
Catalytic Pyrolysis of Torrefied Municipal Solid Waste to sustainable bio‐oil. ABSTRACT South Africa faces growing municipal solid waste (MSW) accumulation and energy insecurity due to fossil fuel dependence. Torrefaction improves MSW for waste‐to‐energy use, while conventional pyrolysis produces low‐quality oxygen‐rich bio‐oil.
Ahmed Mohammed Inuwa, Victor Oluwafemi Fatokun, Usman Mohammed Aliyu, Emmanuel Kweinor Tetteh, Sudesh Rathilal   +4 more
wiley   +1 more source

Assessing stakeholder readiness for implementation of a diabetes prevention programme for patients with recent gestational diabetes: a short report. [PDF]

BMJ Open Qual
Sushko K, Sriskandarajah A, Ali S, Racey M, Rahman I, Sahye-Pudaruth S, Sherifali D, Smith K, Zehra A, Lipscombe L.   +9 more
europepmc   +1 more source