Results 231 to 240 of about 7,859 (293)

EZH2 Inhibition and Myeloid Risk: A Feature of On-Target Biology. [PDF]

Clin Cancer Res
Alumkal JJ, Ellis L.
europepmc   +1 more source

The Gut–Brain Axis in Parkinson's Disease: From Clinical Observation toward Mechanism‐Based Precision Medicine

Movement Disorders, EarlyView.
Abstract Gastrointestinal dysfunction is increasingly recognized as a core feature of Parkinson's disease (PD), affecting quality of life, nutrition, medication response, and potentially the earliest stages of pathogenesis. This perspective traces the evolution of the gut from a neglected source of non‐motor symptoms to a central component of ...
Filip Scheperjans, Per Borghammer, Ronald F. Pfeiffer, Silke Appel‐Cresswell, Ali Keshavarzian   +4 more
wiley   +1 more source

Extrusion-modulated DnaA activity oscillations coordinate DNA replication with biomass growth. [PDF]

Elife
Li D, Zheng H, Bai Y, Zhang Z, Cheng H, Huang X, Wei T, Chang M, Zaritsky A, Hwa T, Liu C.   +10 more
europepmc   +1 more source

Needle in a haystack: Holocene history of European larch in Central Europe revisited

PLANTS, PEOPLE, PLANET, EarlyView.
Defining nativity of species is crucial for their management. However, this is a complex task, especially for species that have been used and spread by humans for a long time. We combined paleoecological records with extensive genetic data to investigate the Holocene history of European larch—a common and economically important tree species in Central ...
Martin Prach, Petr Pokorný, Kristýna Hošková, Daniel Vondrák, Pavel Bednář, Jindřich Prach, Jana Hanzal Šedivá, Hana Drahošová, Kateřina Podrábská, Přemysl Bobek, Jan Smyčka, Tomáš Fér   +11 more
wiley   +1 more source

Structures of DnaA domain I reveal a dimer conserved across Actinomycetes. [PDF]

Nucleic Acids Res
Ellis PK, Srinivasu BY, Chavez Orozco J, Wray GA, Wales TE, Schumacher MA.   +5 more
europepmc   +1 more source

Evaluation of Time to Metastasis After Prostatectomy as a Prognostic Factor in Patients With Metachronous mHSPC: A Secondary Analysis of the SWOG‐1216 Phase 3 Trial

The Prostate, EarlyView.
ABSTRACT Background The prognostic significance of time to metastasis (TTM) following radical prostatectomy in patients with metachronous metastatic hormone‐sensitive prostate cancer (mHSPC) remains uncertain. We performed a secondary analysis of patient‐level data from the phase 3 SWOG 1216 randomized clinical trial to evaluate whether TTM is ...
Nicolas Sayegh, Yeonjung Jo, Umang Swami, Varun Nandakumar, Georges Gebrael, Zeynep Irem Ozay, Haoran Li, Krishnam Goel, Benjamin L. Maughan, Melissa Plets, Maha H. A. Hussain, Tanya B. Dorff, Primo N. Lara Jr., Amir Goldkorn, Seth P. Lerner, Neeraj Agarwal   +15 more
wiley   +1 more source

Impact of lipid-based nutritional supplementation on cardio metabolic risk factors in underweight pre-eclamptic primigravidas: A randomized controlled trial. [PDF]

BMC Pregnancy Childbirth
Zafar H, Mubaraki MA, Zafar M, Sher N, Nazli R, Tariq K, Khan H, Ahmad I, Fozia F.   +8 more
europepmc   +1 more source

Geometric Characterization of LEO–GEO Inter‐Satellite Links for Bidirectional Communications

International Journal of Satellite Communications and Networking, EarlyView.
ABSTRACT Incorporating geosynchronous Earth orbit (GEO) and low Earth orbit (LEO) satellites can extend communication services far beyond the reach of terrestrial infrastructure. A key enabler of such architectures is the establishment of inter‐satellite links (ISLs) between LEOs and GEOs to support bidirectional communications.
Muhammad Furqan, Lingfeng Ye, Yanming Feng   +2 more
wiley   +1 more source

Overcoming resistance barriers: Using the salvage therapy of Ceftazidime-Avibactam and Aztreonam for difficult-to-treat gram-negative infections at a tertiary care hospital in Karachi-A retrospective cohort pilot. [PDF]

Pak J Med Sci
Sarfaraz S, Zafar SM, Siddiqui NA, Hanif MH, Hussain Z.   +4 more
europepmc   +1 more source