Results 151 to 160 of about 1,409,521 (314)

Efficient Evaluation of the Number of False Alarm Criterion

, 2018
This paper proposes a method for computing efficiently the significance of a parametric pattern inside a binary image. On the one hand, a-contrario strategies avoid the user involvement for tuning detection thresholds, and allow one to account fairly for
Aldea, Emanuel, Hégarat-Mascle, Sylvie Le, Vandoni, Jennifer   +2 more
core   +3 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A dual role for the chromatin reader ORCA/LRWD1 in targeting the origin recognition complex to chromatin. [PDF]

EMBO J, 2023
Sahu S, Ekundayo BE, Kumar A, Bleichert F.   +3 more
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Bio-Communication of Bacteria and its Evolutionary Interrelations to Natural Genome Editing Competences of Viruses [PDF]

, 2008
Communicative competences enable bacteria to develop, organise and coordinate rich social life with a great variety of behavioral patterns even in which they organise themselves like multicellular organisms.
Guenther Witzany
core   +2 more sources

Persistent topology for natural data analysis - A survey

, 2017
Natural data offer a hard challenge to data analysis. One set of tools is being developed by several teams to face this difficult task: Persistent topology.
A Adcock, A Cerri, A Cerri, A Cerri, A Hatcher, A Holzinger, A Micheletti, A Verri, C Giusti, D Giorgi, DE Platt, F Belchí, G Carlsson, G Carlsson, G Petri, H Edelsbrunner, HI Ringermacher, I Stanganelli, J Lamar-León, K Turner, L Bigo, L-D Lord, M Dehmer, M Ferri, M Ferri, M Ferri, MG Bergomi, MK Chung, P Bubenik, P Donatini, P Donatini, P Donatini, P Frosini, S Banerjee, S Banerjee, S Biasotti, YV Bazaikin   +36 more
core   +1 more source

PAP8/pTAC6 Is Part of a Nuclear Protein Complex and Displays RNA Recognition Motifs of Viral Origin [PDF]

, 2022
Louise Chambon, François‐Xavier Gillet, Maha Chieb, David Cobessi, Thomas Pfannschmidt, Robert Blanvillain   +5 more
openalex   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Inability of spatial transformations of CNN feature maps to support invariant recognition

, 2020
A large number of deep learning architectures use spatial transformations of CNN feature maps or filters to better deal with variability in object appearance caused by natural image transformations. In this paper, we prove that spatial transformations of
Finnveden, Lukas, Jansson, Ylva, Lindeberg, Tony, Maydanskiy, Maksim   +3 more
core  

A new homeostatic model of the T cell system

, 2010
Our main tenet argues that the primary role of positive thymic selection and the resulting T cell population is the maintenance of a homeostatic equilibrium with self MHC-self peptide complexes.
Bakacs, Tibor, Szabados, Tamas
core   +1 more source