Results 21 to 30 of about 2,974 (211)

Oritavancin Diphosphate [PDF]

open access: yesHospital Pharmacy, 2014
Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing
Dennis J, Cada, Danial E, Baker
openaire   +2 more sources

In Vitro and In Vivo Studies of Oritavancin and Fosfomycin Synergism against Vancomycin-Resistant Enterococcus faecium

open access: yesAntibiotics, 2022
Therapeutic options for infections caused by vancomycin-resistant enterococci are currently suboptimal. Combination regimens where fosfomycin is used alongside existing treatments are emerging given the proven synergistic potential and PK/PD properties ...
Cristina Lagatolla   +4 more
doaj   +1 more source

Review of oritavancin for the treatment of acute bacterial skin and skin structure infections [PDF]

open access: yesFarmacia Hospitalaria, 2018
Objective: To assess critically oritavancin, a second-generation lipoglycopeptide, for the treatment of Acute Bacterial Skin and Skin Structure Infections caused by susceptible Gram-positive bacteria, including methicillin-resistant Staphylococcus ...
Ana Alejandra García Robles   +4 more
doaj   +1 more source

Antimicrobial Activity of the Quinoline Derivative HT61 against Staphylococcus aureus Biofilms. [PDF]

open access: yes, 2020
Staphylococcus aureus biofilms are a significant problem in health care settings, partly due to the presence of a nondividing, antibiotic-tolerant subpopulation. Here we evaluated treatment of S.
Allan, RN   +7 more
core   +2 more sources

Development and validation of a chemostat gut model to study both planktonic and biofilm modes of growth of Clostridium difficile and human microbiota [PDF]

open access: yes, 2014
Copyright: 2014 Crowther et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ...
Baines, Simon D.   +6 more
core   +6 more sources

Clinical Outcomes and Economic Impact of Oritavancin for Gram-Positive Infections: A Single Academic Medical Center Health System Experience

open access: yesDrugs - Real World Outcomes, 2020
Background Vancomycin treatment of complicated Gram-positive infections is associated with laboratory monitoring, nephrotoxicity, and multiple daily dosing.
Lauren E. Brownell   +6 more
doaj   +1 more source

Molecular dynamics simulations of the secondary-binding site in disaccharide-modified glycopeptide antibiotics

open access: yesScientific Reports, 2022
Oritavancin is a semisynthetic glycopeptide antibiotic used to treat severe infections by multidrug-resistant Gram-positive pathogens. Oritavancin is known to be a thousand times more potent than vancomycin against Gram-positive bacteria due to the ...
Olatunde P. Olademehin   +2 more
doaj   +1 more source

Oritavancin polymethylmethacrylate (PMMA)—compressive strength testing and in vitro elution

open access: yesJournal of Orthopaedic Surgery and Research, 2019
Background Polymethylmethacrylate (PMMA) is used for local antimicrobial delivery in orthopedic infection. Oritavancin is a long half-life lipoglycopeptide with broad activity against Gram-positive bacteria.
Suzannah M. Schmidt-Malan   +4 more
doaj   +1 more source

The Real-World Economic and Clinical Management of Adult Patients with Skin and Soft Tissue Infections (SSTIs) with Oritavancin: Data from Two Multicenter Observational Cohort Studies

open access: yesDrugs - Real World Outcomes, 2020
Background Oritavancin is a FDA-approved single-dose IV therapy for the treatment of acute bacterial skin and skin structure infections caused (or suspected to be caused) by certain Gram-positive pathogens, including methicillin-resistant Staphylococcus ...
Sandy Estrada   +3 more
doaj   +1 more source

Single-Dose Oritavancin Treatment of Acute Bacterial Skin and Skin Structure Infections: SOLO Trial Efficacy by Eron Severity and Management Setting. [PDF]

open access: yes, 2016
INTRODUCTION: Introduction of new antibiotics enabling single-dose administration, such as oritavancin may significantly impact site of care decisions for patients with acute bacterial skin and skin structure infections (ABSSSI).
C Marwick   +8 more
core   +2 more sources

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