Results 181 to 190 of about 119,102 (282)

Biosynthesis of Kaitocephalin: A Neuroprotective Natural Product Featuring a Peptide‐Like yet Nonpeptidic Scaffold

Angewandte Chemie, Volume 138, Issue 13, 23 March 2026.
Kaitocephalin (KCP) is a neuroprotective fungal metabolite with a unique scaffold of amino acids linked via C–C bonds. Genome‐transcriptome analyses identified its biosynthetic gene cluster (kpb cluster) in Eupenicillium shearii. LC‐MS/MS profiling identified four new KCP‐related compounds.
Yukari Maeno, Taro Shiraishi, Naoya Saito, Jun‐ichi Maruyama, Kazuo Shin‐ya, Tomohisa Kuzuyama   +5 more
wiley   +2 more sources

Amino acid decarboxylation preserves <i>Salmonella</i> fitness during phagocyte-derived oxidative stress. [PDF]

mBio
Margolis A, Liu L, Kim J-S, Porwollik S, McClelland M, Vázquez-Torres A.   +5 more
europepmc   +1 more source

Forward genetic screening of mutants of the wild diploid ancestor Nicotiana sylvestris identifies aspartate oxidase 2 as a key gene for nicotine biosynthesis in cultivated allotetraploid tobacco (Nicotiana tabacum)

The Plant Journal, Volume 126, Issue 1, April 2026.
SUMMARY Tobacco (Nicotiana tabacum) is one of the most important commercial crops. It is an allotetraploid with two subgenomes derived from two wild diploid species: the maternal ancestor Nicotiana sylvestris and the paternal ancestor Nicotiana tomentosiformis.
Takanori Takeuchi, Hisashi Udagawa, Masao Arai, Ryo Nishiguchi, Tsubasa Yoshikiyo, Tomoyuki Tajima, Hiroshi Magome, Yoshimitsu Takakura   +7 more
wiley   +1 more source

Amino acid and viral binding by the high-affinity Cationic Amino acid Transporter 1 (CAT1) from Mus musculus. [PDF]

Nat Commun
Ye M, Liang Z, Zhou D, Pike ACW, Wang S, Wang D, Bakshi S, Brooke L, Williams EP, Elkins JM, Kessler BM, Stuart DI, Sauer DB.   +12 more
europepmc   +1 more source

Oxygen and glucose supplementation increases rates of linear growth and cell proliferation in growth‐restricted fetal sheep

The Journal of Physiology, Volume 604, Issue 7, Page 2778-2795, 1 April 2026.
Abstract figure legend Effects of sustained oxygen and glucose supplementation on growth and cellular proliferation in growth‐restricted fetuses. This study evaluated whether supplemental oxygen and glucose could improve growth rates in sheep fetuses with established fetal growth restriction (FGR). Following the induction of placental insufficiency and
Mariangel Varela, Daniel B. Chrisenberry, Eliza H. Johnson, Rosa I. Luna‐Ramirez, Ayna R. Tracy, Sanya Kathuria, Weicheng Zhao, Miranda J. Anderson, Laura D. Brown, Sean W. Limesand   +9 more
wiley   +1 more source

Gut microbiota L-ornithine promotes resistance to obesity through metabolites mediated immunosuppressive macrophages. [PDF]

Cell Mol Life Sci
Li Y, Liu Y, Wang J, Gao Y, Zhang Y, Yang R.   +5 more
europepmc   +1 more source

Report of the Scientific Committee of the Spanish Agency for Food Safety and Nutrition (AESAN) on the risk of food poisoning due to the presence of biogenic amines in meals made from chicken meat consumed by children under 3 years of age

Food Risk Assess Europe, Volume 4, Issue 2, April 2026.
Abstract Biogenic amines are low molecular weight organic bases that come from the enzymatic decarboxylation of amino acids. They are present in many types of food, with the highest concentrations usually found in fish and their derived products, as well as in beverages and fermented foods of plant, meat and dairy origin.
Baltasar Mayo Pérez, Houda Berrada Ramdani, Rosa María Capita González, Ángel José Gutiérrez Fernández, Silvia Pichardo Sánchez, María Roser Vila Casanovas   +5 more
wiley   +1 more source

Exploring the link between ruminal methane production and physiological changes in Japanese Black cattle during fattening. [PDF]

Sci Rep
Lee H, Kim M, Masaki T, Ikuta K, Iwamoto E, Oikawa K, Oh K, Nonaka I, Ashihara A, Uemoto Y, Haga S, Terada F, Roh S.   +12 more
europepmc   +1 more source

ALOX15‐Derived Oxylipins Attenuate Macrophage Inflammatory Signaling Via a Gαq–PLC–PKC Pathway

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
ALOX15 expression and its downstream oxylipins, including 12‐HETE and 13‐HODE, are induced in intestinal epithelial and lamina propria immune cells during the early and middle phases of experimental colitis. These endogenous lipid mediators suppress lipopolysaccharide‐induced TNF‐α and IL‐6 production in macrophages without affecting cell viability ...
Adrian Hilman, Yoshiki Ishii, Bambang Dwi Wijatniko, Dina Mustika Rini, Takuya Suzuki   +4 more
wiley   +1 more source

Molecular mechanisms and therapies for tumor inhibition through the arginine metabolism pathway. [PDF]

Front Oncol
Xu Y, Yu M, Zhang Y, Jiang Y, Zhu H, He S, Yu G, Li N, Liu S, Liu B.   +9 more
europepmc   +1 more source