Results 201 to 210 of about 81,019 (308)

Intestinal Polyamine Metabolism and Mucosal Barrier in Ningxiang and DLY Piglets: Differential Responses to ETEC Challenge. [PDF]

Animals (Basel)
Song Y, Feng L, Meng Y, Cheng H, Wang J, Yue Y.   +5 more
europepmc   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, Volume 13, Issue 32, 9 June 2026.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source

Isolation and characterization of Saccharomyces cerevisiae mutants with ornithine accumulation for value-added craft beer brewing. [PDF]

J Ind Microbiol Biotechnol
Nishimura A, Isogai S, Yamada K, Tanahashi R, Takagi H.   +4 more
europepmc   +1 more source

Exogenous γ-aminobutyric acid promotes 2-acetyl-1-pyrroline biosynthesis by enriching glutamate and optimizing its metabolic flux in pumpkin. [PDF]

Front Plant Sci
Chang J, Zhu X, Ye X, Li J, Chen X, Li J, Zhang B.   +6 more
europepmc   +1 more source

Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics

Annals of Neurology, Volume 99, Issue 6, Page 1571-1588, June 2026.
Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian, Jianing Shen, Linwei Tian, Jinghui Li, Lu Yang, Bo Yuan, Shulin Li, Yuyu Niu, Lu Zhao, Jingkuan Wei   +9 more
wiley   +1 more source

Acute effect of citrulline malate on flow-mediated dilation and serum pharmacodynamics in healthy young males. [PDF]

Front Physiol
Grannes J, Callender NA, Gonzalez AM, Hisdal J, Vårvik FT, Bjørnsen T.   +5 more
europepmc   +1 more source

The Development and Characterization of a Panel of Amine Dehydrogenases (AmDHs) and Amino Acid Dehydrogenases (AADHs)

ChemCatChem, Volume 18, Issue 11, 15 June 2026.
The CoE‐AmDH panel enables sustainable access to chiral amines using diverse amine (AmDH) and amino acid dehydrogenases (AADH). Utilizing formate (FDH) or glucose dehydrogenase (GDH) for cofactor regeneration, this study establishes a robust screening platform for mild reductive aminations.
R. Tilly Bradshaw Allen, William R. Birmingham, Nicholas John Turner   +2 more
wiley   +1 more source

Phenotype-Aligned Metabolomics Identifies Plasma Arginine as a Candidate Predictor of Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage. [PDF]

Transl Stroke Res
Urbanowicz K, Wiśniewski K, Opiełka M, Bieńkowski M, Popęda M, Krajewski O, Bobeff EJ, Zaczkowski K, Szmyd B, Jaskólski DJ, Smoleński RT.   +10 more
europepmc   +1 more source

Lactobacillus Is Associated With Disease in Pulmonary Arterial Hypertension: A Prospective Cohort Study

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
Study overview: simultaneous right heart catheterization, gut microbiome analysis, and plasma blood metabolomics in a cohort of prevalent pulmonary arterial hypertension patients. Key findings: gut microbial Lactobacillus species associated with altered gut‐derived metabolite levels, superior measures of right ventricular structure and function, and ...
Arun Jose, Senu Apewokin, Nicholas J. Ollberding, Qing Duan, Jennifer Trannguyen, Sasha Z. Prisco, Thenappan Thenappan, Anna R. Hemnes, Jean M. Elwing   +8 more
wiley   +1 more source