Abstract figure legend Overview of cerebral small vessel disease (cSVD) pathophysiology and current modelling challenges. Left: clinical burden and key unresolved research questions. Right: neurovascular unit (NVU) architecture highlighting sites of cSVD pathology across arterioles, capillaries and venules, including interactions between endothelial ...
Sophie Beaumont +3 more
wiley +1 more source
The Multi-dimensional Mechanisms and Transformation Prospects of the Intratumoral Microbiota-Arginine Metabolism Axis in Tumor Progression and Immune Regulation. [PDF]
Yu S +7 more
europepmc +1 more source
Target‐induced disulfide ligation of PNA twin probes promotes pyrene excimer formation for nucleic acid detection. ABSTRACT The development of methods for detecting specific nucleic acids is important for early diagnosis and treatment of diseases at the genetic level.
Yutaka Ouchi +9 more
wiley +1 more source
Recent advances in nonprotein amino acids: insights from function to biosynthesis. [PDF]
Zou Y +9 more
europepmc +1 more source
First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders
ABSTRACT This guideline summarizes diagnostic and therapeutic approaches based on a systematic literature review and evidence evaluation using the GRADE methodology. Given the limited high‐quality data, expert consensus was additionally obtained through a modified Delphi process.
Giorgia Olivieri +26 more
wiley +1 more source
Synthesis of Amines for Active Pharmaceutical Ingredients Using the Whole-Cell Factory Saccharomyces Cerevisae. [PDF]
Kwiatos N, Ossel S, Mutti FG.
europepmc +1 more source
THE PREPARATION OF CRYSTALLINE ORNITHINE. THE PICRATES AND MONOSULFATES OF ORNITHINE
Hubert Bradford Vickery, Charles A. Cook
openaire +1 more source
Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva +5 more
wiley +1 more source
Correction: Deguelin inhibits growth and prolactin synthesis in prolactinomas by targeting the PI3K/AKT/CREB3L1 pathway and ornithine decarboxylase. [PDF]
Gong L +13 more
europepmc +1 more source

