Results 221 to 230 of about 119,102 (282)

A biosynthetic pathway for ornithine lipid formation dependent on a GH3 (Gretchen Hagen 3)-like enzyme in planctomycetes. [PDF]

open access: yesJ Biol Chem
Rivera-Najera LY   +9 more
europepmc   +1 more source
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Ornithine phenylacetate revisited

Metabolic Brain Disease, 2013
In patients with liver failure hyperammonemia is associated with the development of hepatic encephalopathy (HE) and immune impairment. Treatment of hyperammonemia is an unmet clinical need. Ornithine phenylacetate (OP) is a novel drug that is targeted at reducing ammonia concentration in patients with liver disease and therefore a potential treatment ...
Maria, Jover-Cobos   +3 more
openaire   +2 more sources

Crystalline ornithine transcarbamylase

Biochimica et Biophysica Acta (BBA) - Enzymology, 1967
Abstract Ornithine transcarbamylase (carbamoyl phosphate: l -ornithine carbamoyl transferase, EC 2.1.2.2) from arginine grown Streptococcus D10 cells was purified to homogeneity by acid, solvent, heat, and salt fractionation. The enzyme was then crystallized from an ammonium sulfate solution. Some molecular properties of the enzyme are described.
S H, Bishop, S, Grisolia
openaire   +2 more sources

Ornithine metabolism along the female mouse nephron: localization of ornithine decarboxylase and ornithine aminotransferase

Pflügers Archiv - European Journal of Physiology, 2000
The fate of ornithine in the nephron of the female OF-1 Swiss mouse remains unknown. The aim of the present study was to identify the nephron segments containing the key enzymes involved in ornithine metabolism: ornithine decarboxylase (ODC) and ornithine aminotransferase (OAT).
Levillain, O.   +3 more
openaire   +3 more sources

Ornithine aminotransferase activity, tissue ornithine concentrations and polyamine metabolism

International Journal of Biochemistry, 1989
1. Inactivation of L-ornithine:2-oxoacid aminotransferase (OAT) by 5-fluoromethylornithine (5FMOrn), a specific inactivator of OAT, causes a great elevation of tissue ornithine (Orn) concentrations. 2. Inhibition of L-ornithine decarboxylase (ODC) by 2-difluoromethylornithine (DFMO) had no effect on Orn concentrations. 3. The combined administration of
N, Seiler   +3 more
openaire   +2 more sources

Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer

Nature, 2023
Min-Sik Lee, Lucas Dailey, George Ye
exaly  

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