Results 101 to 110 of about 24,134 (239)

Xenobiotic induction of cytochrome P450 2B1 (CYP2B1) is mediated by the orphan nuclear receptor constitutive androstane receptor (CAR) and requires steroid co-activator 1 (SRC-1) and the transcription factor Sp1 [PDF]

, 2001
Roongsiri Muangmoonchai, Despina Smirlis, Siew Cheng Wong, Mina Edwards, Ian Phillips, Elizabeth A. Shephard   +5 more
openalex   +1 more source

Supplementary Figure 2 from The Orphan Nuclear Receptor NR4A1 (Nur77) Regulates Oxidative and Endoplasmic Reticulum Stress in Pancreatic Cancer Cells [PDF]

, 2023
Syng‐Ook Lee, Un‐Ho Jin, Jeong Han Kang, Sang Bae Kim, Aaron S. Guthrie, Sandeep Sreevalsan, Ju‐Seog Lee, Stephen Safe   +7 more
openalex   +1 more source

Integrating the In‐Laws: Class and Kin Support Within Marriage in Urban Kenya

Journal of Marriage and Family, EarlyView.
ABSTRACT Objective This study compares affinal kin relationships in low‐income and higher‐income families in Nairobi, Kenya. Background In most studies of kinship structure and relationships in sub‐Saharan Africa, culture serves as the basis upon which norms and expectations of kin are differentiated.
Kirsten Stoebenau, Nikita Viswasam, Estelle M. Sidze, Sangeetha Madhavan   +3 more
wiley   +1 more source

Prolonged exposure to artificial light and carcinogenesis: A systematic review of oncostatic mechanisms associated with melatonin pathways

Photochemistry and Photobiology, EarlyView.
Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza, Jêmina Oliveira, Antônio Ferreira, Renan Lopes, Marli Cupertino   +4 more
wiley   +1 more source

Impacts of exercise, renin–angiotensin system modulation or both on skeletal muscle circadian gene expression

Experimental Physiology, EarlyView.
Abstract Ageing negatively affects quality of life and healthspan, and interventions are needed to slow this progressive decline. Previously, we have demonstrated the potential functional benefits of combining a genetically modified probiotic (GMP) targeting the non‐canonical arm of the renin–angiotensin system (RAS) with exercise training.
Emily L. Zumbro, Liliana C. Baptista, Taylor Taylor, Abbi R. Hernandez, Anisha Banerjee, Yi Sun, YouFeng Yang, Qiuhong Li, Thomas W. Buford   +8 more
wiley   +1 more source

Orphan nuclear receptor Nur77 Inhibits Oxidized LDL-induced differentiation of RAW264.7 murine macrophage cell line into dendritic like cells [PDF]

, 2014
Liuhua Hu, Yingyan Yu, Shuxuan Jin, Peng Nie, Zhaohua Cai, Mingli Cui, Shiqun Sun, Hua Xiao, Qin Shao, Linghong Shen, Ben He   +10 more
openalex   +1 more source

Opportunities and challenges in protein structure prediction

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract Deep learning methods, particularly exemplified by AlphaFold2, have revolutionized the field of protein structure prediction—an achievement recognized by the 2024 Nobel Prize in Chemistry awarded to its core developers. Despite this remarkable achievement, the broader protein folding problem is far from solved. Key challenges—each representing
Wenkai Wang, Baoquan Su, Chenxiao Xiang, Jianyi Yang   +3 more
wiley   +1 more source

Targeting the Membrane‐Embedded Rhomboid Protease GlpG: A Multimodal Strategy for Inhibitor Discovery and Mechanistic Insight

Angewandte Chemie, Volume 138, Issue 10, 2 March 2026.
Created in BioRender. Bohg, C. (2026) https://BioRender.Com/ vi9hi4f. Rhomboid proteases are a mechanistically unique and evolutionarily conserved protein family. Despite their pharmacological relevance, the development of selective inhibitors has lagged behind that of soluble proteases.
Claudia Bohg, Yurii Dubanych, Spyridon Kosteletos, Taoran Xiao, Martin Neuenschwander, Tillmann Utesch, Michael Lisurek, Carl Öster, Andreas Oder, Carola Seyffarth, Kathrin Bach, Denise‐Liù Gracias Leone, František Filandr, Marc Wegert, Sascha Lange, Henry Sawczyc, Jens Peter von Kries, Christian P. R. Hackenberger, Edgar Specker, Han Sun, Kvido Stříšovský, Adam Lange   +21 more
wiley   +2 more sources

Selective regulation of nuclear orphan receptors 4A by adenosine receptor subtypes in human mast cells [PDF]

, 2010
Li Zhang, Catherine Paine, Ramiro Dip
openalex   +1 more source

Narrative formatting, chronotopic orderings, and moralization in ex‐gay stories

Journal of Linguistic Anthropology, Volume 36, Issue 1, May 2026.
Abstract Formatted stories rely on spatiotemporal cues to evoke recognizability through linearity, which prescribes a particular template for meaning‐making. This article examines stories narrated by ex‐gay members of a Christian organization in Singapore and considers how chronotopes within the stories are ordered to regiment ways of feeling for ...
Vincent Pak
wiley   +1 more source