Results 1 to 10 of about 11,628 (248)

An Update of Orthopoxvirus Molecular Evolution [PDF]

Viruses, 2022
Although variola virus (VARV) has been eradicated through widespread vaccination, other orthopoxviruses pathogenic for humans circulate in nature. Recently, new orthopoxviruses, including some able to infect humans, have been found and their complete ...
Igor V. Babkin, Irina N. Babkina, Nina V. Tikunova   +2 more
doaj   +5 more sources

Skin lesions caused by Orthopoxvirus, cowpox - case report from Poland

Journal of Education, Health and Sport, 2021
Background:Despite the elimination of smallpox, other orthopoxviruses, including cowpox virus, still infect humans. Wild rodents are its natural reservoir.
Konrad Kania, Maria Kalicka, Tomasz Korzec, Przemyslaw Raczkiewicz, Monika Kuc   +4 more
doaj   +3 more sources

Monkeypox Virus: Epidemiology, Virology, Diagnosis, Vaccine, and Therapeutics. [PDF]

MedComm (2020)
This review provides a comprehensive overview of the latest research advances in MPXV, with a focused analysis across five core dimensions: epidemiology, virology, diagnosis, vaccine, and therapeutics. The primary objective of this review is to advance the understanding of MPXV and facilitate the development of more effective diagnostic methods ...
Yan Y, Sun Y, Sun G, Niu C, Zhao X, Zhao M, Liu T, Zhang S, Zhai H, Liu A, Yu S, Pan S, Zhong W, Zhang Y, Li S.   +14 more
europepmc   +2 more sources

Does Lumpy Skin Disease Have the Potential to Become Zoonotic? [PDF]

J Med Virol
Journal of Medical Virology, Volume 97, Issue 8, August 2025.
Velazquez-Salinas L, Harvey AM, Mire C.
europepmc   +2 more sources

Mpox With Digestive Manifestations in a 16-Year-Old Adolescent Girl: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Mpox, primarily known for cutaneous and mucosal manifestations, can present atypically. This case reports a rare digestive form with peritonitis in a 16‐year‐old girl. A febrile adolescent presented with acute abdominal pain, peritonitis, systemic inflammation, anemia, and ionic disturbances.
Mjumbe CK, Bafurume JM, Munianji EM, Tague C, Akilimali A.   +4 more
europepmc   +2 more sources

Comparative pathogenicity of vaccinia virus and mpox virus infections in CAST/EiJ mice: Exploring splenomegaly and transcriptomic profiles. [PDF]

Animal Model Exp Med
We successfully constructed CAST/EiJ mice models infected with low‐dose vaccinia virus (VACV‐L), high‐dose VACV (VACV‐H), and mpox virus (MPXV), demonstrating that VACV‐L and MPXV infections induced splenomegaly in mice, and VACV‐H infection caused mortality in mice.
Hou Y, Ma J, Huang B, Li N, Zhu L, Jia Z, Yang J, Zhang J, Tan W, Xue J.   +9 more
europepmc   +2 more sources

Vaccinia and Monkeypox Virus-Neutralizing Antibodies in People Living with HIV: A Serological Study in a Orthopoxvirus-Endemic, Low-Income Region in Brazil [PDF]

Pathogens
Co-infections of Orthopoxviruses (OPVs), such as vaccinia virus (VACV) and monkeypox virus (MPXV), and the human immunodeficiency virus (HIV) can be associated with severe outcomes.
Thyago José Silva, Ana Gabriella Stoffella-Dutra, Victor Lacerda Gripp, Pollyana R. C. Gorgens, Iago José da Silva Domingos, Pedro Henrique Bastos e Silva, Bruna Caroline Chaves-Garcia, Erna Geessien Kroon, Etel Rocha-Vieira, Giliane de Souza Trindade, Danilo Bretas de Oliveira   +10 more
doaj   +2 more sources

Orthopoxvirus Seroprevalence and Infection Susceptibility in France, Bolivia, Laos, and Mali

Emerging Infectious Diseases, 2022
To determine a demographic overview of orthopoxvirus seroprevalence, we tested blood samples collected during 2003–2019 from France (n = 4,876), Bolivia (n = 601), Laos (n = 657), and Mali (n = 255) for neutralizing antibodies against vaccinia virus. In
Léa Luciani, Nathanaël Lapidus, Abdennour Amroun, Alessandra Falchi, Chanthala Souksakhone, Mayfong Mayxay, Audrey Dubot-Pérès, Paola Mariela Saba Villarroel, Issa Diarra, Ousmane Koita, Pierre Gallian, Xavier de Lamballerie   +11 more
doaj   +1 more source

Priming stroma with a vitamin D analog to optimize viroimmunotherapy for pancreatic cancer

Molecular Therapy: Oncolytics, 2022
Pancreatic cancer resistance to immunotherapies is partly due to deficits in tumor-infiltrating immune cells and stromal density. Combination therapies that modify stroma and recruit immune cells are needed.
Sang-In Kim, Shyambabu Chaurasiya, Venkatesh Sivanandam, Seonah Kang, Anthony K. Park, Jianming Lu, Annie Yang, Zhifang Zhang, Isabella A. Bagdasarian, Yanghee Woo, Joshua T. Morgan, Zhirong Yin, Yuman Fong, Susanne G. Warner   +13 more
doaj   +1 more source

Human Monkeypox without Viral Prodrome or Sexual Exposure, California, USA, 2022

Emerging Infectious Diseases, 2022
We report human monkeypox in a man who returned to the United States from the United Kingdom and reported no sexual contact. He had vesicular and pustular skin lesions but no anogenital involvement.
Abraar Karan, Ashley R. Styczynski, ChunHong Huang, Malaya K. Sahoo, Krithika Srinivasan, Benjamin A. Pinsky, Jorge L. Salinas   +6 more
doaj   +1 more source