An Update of Orthopoxvirus Molecular Evolution [PDF]
Although variola virus (VARV) has been eradicated through widespread vaccination, other orthopoxviruses pathogenic for humans circulate in nature. Recently, new orthopoxviruses, including some able to infect humans, have been found and their complete ...
Igor V. Babkin+2 more
doaj +4 more sources
Orthopoxvirus DNA in Eurasian Lynx, Sweden [PDF]
Cowpox virus, which has been used to protect humans against smallpox but may cause severe disease in immunocompromised persons, has reemerged in humans, domestic cats, and other animal species in Europe.
Morten Tryland+5 more
doaj +10 more sources
Estimation of anti-orthopoxvirus immunity in Moscow residents and potential risks of spreading Monkeypox virus [PDF]
WHO has declared the outbreak of monkeypox as a public health emergency of international concern. In less than three months, monkeypox was detected in more than 30 000 people and spread to more than 80 countries around the world.
Vladimir A. Gushchin+40 more
doaj +3 more sources
Vaccinia and Monkeypox Virus-Neutralizing Antibodies in People Living with HIV: A Serological Study in a Orthopoxvirus-Endemic, Low-Income Region in Brazil [PDF]
Co-infections of Orthopoxviruses (OPVs), such as vaccinia virus (VACV) and monkeypox virus (MPXV), and the human immunodeficiency virus (HIV) can be associated with severe outcomes.
Thyago José Silva+10 more
doaj +3 more sources
Ectromelia Virus Infections of Mice as a Model to Support the Licensure of Anti-Orthopoxvirus Therapeutics [PDF]
The absence of herd immunity to orthopoxviruses and the concern that variola or monkeypox viruses could be used for bioterroristic activities has stimulated the development of therapeutics and safer prophylactics.
R. Mark Buller+4 more
doaj +2 more sources
Orthopoxvirus Seroprevalence and Infection Susceptibility in France, Bolivia, Laos, and Mali
To determine a demographic overview of orthopoxvirus seroprevalence, we tested blood samples collected during 2003–2019 from France (n = 4,876), Bolivia (n = 601), Laos (n = 657), and Mali (n = 255) for neutralizing antibodies against vaccinia virus. In
Léa Luciani+11 more
doaj +2 more sources
Identification of neutralizing nanobodies protecting against poxvirus infection [PDF]
An outbreak of mpox has triggered concerns regarding the adequacy of intervention strategies. Passive immunity conferred by neutralizing antibodies exhibits potential in the prophylaxis and treatment of orthopoxvirus infections.
Xuehua Yang+15 more
doaj +2 more sources
Orthopoxvirus zoonosis: A potential threat across the Balkan countries. [PDF]
Manuka A+5 more
europepmc +2 more sources
Domestic Dogs Exposed to Orthopoxvirus in Urban Areas of Brazil. [PDF]
de Meneses D+10 more
europepmc +2 more sources
The global re-emergence of monkeypox (Mpox) in non-endemic regions in 2022 has highlighted the critical importance of timely virus detection and robust public health surveillance in assessing outbreaks and their impact.
Sumit Aggarwal+5 more
doaj +1 more source