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Skin lesions caused by Orthopoxvirus, cowpox - case report from Poland
Background:Despite the elimination of smallpox, other orthopoxviruses, including cowpox virus, still infect humans. Wild rodents are its natural reservoir.
Konrad Kania +4 more
doaj +3 more sources
Pox-AbDab: the orthopoxvirus antibody database [PDF]
In August 2024, the World Health Organization declared the mpox orthopoxvirus to be a Public Health Emergency of International Concern for the second time in three years, emphasising the need for continued studies into its microbiology and potential ...
Henriette L. Capel +4 more
doaj +2 more sources
Vaccinia and Monkeypox Virus-Neutralizing Antibodies in People Living with HIV: A Serological Study in a Orthopoxvirus-Endemic, Low-Income Region in Brazil [PDF]
Co-infections of Orthopoxviruses (OPVs), such as vaccinia virus (VACV) and monkeypox virus (MPXV), and the human immunodeficiency virus (HIV) can be associated with severe outcomes.
Thyago José Silva +10 more
doaj +2 more sources
An Update of Orthopoxvirus Molecular Evolution
Although variola virus (VARV) has been eradicated through widespread vaccination, other orthopoxviruses pathogenic for humans circulate in nature. Recently, new orthopoxviruses, including some able to infect humans, have been found and their complete ...
Igor V. Babkin +2 more
doaj +1 more source
Priming stroma with a vitamin D analog to optimize viroimmunotherapy for pancreatic cancer
Pancreatic cancer resistance to immunotherapies is partly due to deficits in tumor-infiltrating immune cells and stromal density. Combination therapies that modify stroma and recruit immune cells are needed.
Sang-In Kim +13 more
doaj +1 more source
Human Monkeypox without Viral Prodrome or Sexual Exposure, California, USA, 2022
We report human monkeypox in a man who returned to the United States from the United Kingdom and reported no sexual contact. He had vesicular and pustular skin lesions but no anogenital involvement.
Abraar Karan +6 more
doaj +1 more source
Detecting, Quantifying, and Isolating Monkeypox Virus in Suspected Cases, Spain
When a monkeypox virus outbreak began in several parts of the world in May 2022, timely and accurate diagnosis became mandatory. In our laboratory, a real-time quantitative PCR was designed and evaluated in several patient samples and compared with ...
Marta E. Álvarez Argüelles +9 more
doaj +1 more source
Vaccinia virus is the active component of all modern smallpox vaccines after the mid-20th century, but it is uncertain to what extent cowpox, vaccinia, and horsepox viruses were used to produce vaccines before then.
Aline R. V. Souza +4 more
doaj +1 more source
The French Armed Forces Virology Unit: A Chronological Record of Ongoing Research on Orthopoxvirus
Since the official declaration of smallpox eradication in 1980, the general population vaccination has ceased worldwide. Therefore, people under 40 year old are generally not vaccinated against smallpox and have no cross protection against orthopoxvirus ...
Déborah Delaune +4 more
doaj +1 more source
The absence of herd immunity to orthopoxviruses and the concern that variola or monkeypox viruses could be used for bioterroristic activities has stimulated the development of therapeutics and safer prophylactics.
R. Mark Buller +4 more
doaj +1 more source

