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An Update of Orthopoxvirus Molecular Evolution [PDF]

open access: yesViruses, 2022
Although variola virus (VARV) has been eradicated through widespread vaccination, other orthopoxviruses pathogenic for humans circulate in nature. Recently, new orthopoxviruses, including some able to infect humans, have been found and their complete ...
Igor V. Babkin   +2 more
doaj   +4 more sources

Orthopoxvirus DNA in Eurasian Lynx, Sweden [PDF]

open access: yesEmerging Infectious Diseases, 2011
Cowpox virus, which has been used to protect humans against smallpox but may cause severe disease in immunocompromised persons, has reemerged in humans, domestic cats, and other animal species in Europe.
Morten Tryland   +5 more
doaj   +10 more sources

Estimation of anti-orthopoxvirus immunity in Moscow residents and potential risks of spreading Monkeypox virus [PDF]

open access: goldFrontiers in Immunology, 2022
WHO has declared the outbreak of monkeypox as a public health emergency of international concern. In less than three months, monkeypox was detected in more than 30 000 people and spread to more than 80 countries around the world.
Vladimir A. Gushchin   +40 more
doaj   +3 more sources

Vaccinia and Monkeypox Virus-Neutralizing Antibodies in People Living with HIV: A Serological Study in a Orthopoxvirus-Endemic, Low-Income Region in Brazil [PDF]

open access: goldPathogens
Co-infections of Orthopoxviruses (OPVs), such as vaccinia virus (VACV) and monkeypox virus (MPXV), and the human immunodeficiency virus (HIV) can be associated with severe outcomes.
Thyago José Silva   +10 more
doaj   +3 more sources

Ectromelia Virus Infections of Mice as a Model to Support the Licensure of Anti-Orthopoxvirus Therapeutics [PDF]

open access: goldViruses, 2010
The absence of herd immunity to orthopoxviruses and the concern that variola or monkeypox viruses could be used for bioterroristic activities has stimulated the development of therapeutics and safer prophylactics.
R. Mark Buller   +4 more
doaj   +2 more sources

Orthopoxvirus Seroprevalence and Infection Susceptibility in France, Bolivia, Laos, and Mali

open access: yesEmerging Infectious Diseases, 2022
To determine a demographic overview of orthopoxvirus seroprevalence, we tested blood samples collected during 2003–2019 from France (n = 4,876), Bolivia (n = 601), Laos (n = 657), and Mali (n = 255) for neutralizing antibodies against vaccinia virus. In
Léa Luciani   +11 more
doaj   +2 more sources

Identification of neutralizing nanobodies protecting against poxvirus infection [PDF]

open access: yesCell Discovery
An outbreak of mpox has triggered concerns regarding the adequacy of intervention strategies. Passive immunity conferred by neutralizing antibodies exhibits potential in the prophylaxis and treatment of orthopoxvirus infections.
Xuehua Yang   +15 more
doaj   +2 more sources

Orthopoxvirus zoonosis: A potential threat across the Balkan countries. [PDF]

open access: hybridJ Public Health Res
Manuka A   +5 more
europepmc   +2 more sources

Domestic Dogs Exposed to Orthopoxvirus in Urban Areas of Brazil. [PDF]

open access: goldViruses
de Meneses D   +10 more
europepmc   +2 more sources

Mapping the Landscape of Health Research Priorities for Effective Pandemic Preparedness in Human Mpox Virus Disease

open access: yesPathogens, 2023
The global re-emergence of monkeypox (Mpox) in non-endemic regions in 2022 has highlighted the critical importance of timely virus detection and robust public health surveillance in assessing outbreaks and their impact.
Sumit Aggarwal   +5 more
doaj   +1 more source

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