Experimental intranasal infection of marmosets (Callithrix jacchus) with calpox virus results in fatal disease. Route and dose used for viral inoculation of the test animals mimics the natural transmission of smallpox, thus representing a suitable model ...
Anne Schmitt+7 more
doaj +1 more source
Bovine Vaccinia: Insights into the Disease in Cattle
Bovine vaccinia (BV), caused by Vaccinia virus (VACV), is a zoonosis characterized by exanthematous lesions in the teats of dairy cows and the hands of milkers and is an important public health issue. Severe VACV-induced lesions in the teats and udder of
Ana Carolina Diniz Matos+3 more
doaj +1 more source
CRISPR/Cas9—Advancing Orthopoxvirus Genome Editing for Vaccine and Vector Development
The clustered regularly interspaced short palindromic repeat (CRISPR)/associated protein 9 (Cas9) technology is revolutionizing genome editing approaches.
Arinze Okoli+3 more
doaj +1 more source
Characterization of ATI, TK and IFN-alpha/betaR genes in the genome of the BeAn 58058 virus, a naturally attenuated wild Orthopoxvirus. [PDF]
João T. Marques+6 more
openalex +1 more source
Identification of the Orthopoxvirus p4c Gene, Which Encodes a Structural Protein That Directs Intracellular Mature Virus Particles into A-Type Inclusions [PDF]
Terry A. McKelvey+4 more
openalex +1 more source
New Class of Orthopoxvirus Antiviral Drugs That Block Viral Maturation [PDF]
Chelsea M. Byrd+9 more
openalex +1 more source
Electrostatic Modeling Predicts the Activities of Orthopoxvirus Complement Control Proteins [PDF]
Georgia Sfyroera+4 more
openalex +1 more source
Estimation of anti-orthopoxvirus immunity in Moscow residents and potential risks of spreading Monkeypox virus [PDF]
Vladimir А. Gushchin+35 more
openalex +1 more source
Activity and Mechanism of Action of N -Methanocarbathymidine against Herpesvirus and Orthopoxvirus Infections [PDF]
Mark N. Prichard+3 more
openalex +1 more source
N-(3,3a,4,4a,5,5a,6,6a-Octahydro-1,3-dioxo-4,6- ethenocycloprop[f]isoindol-2-(1H)-yl)carboxamides: Identification of Novel Orthopoxvirus Egress Inhibitors [PDF]
T. R. Bailey+15 more
openalex +1 more source