Results 91 to 100 of about 11,628 (248)
Revolution of AAV in Drug Discovery: From Delivery System to Clinical Application
Journal of Medical Virology, Volume 97, Issue 6, June 2025.ABSTRACT Adeno‐associated virus (AAV) is a non‐enveloped DNA virus infecting a wide variety of species, tissues, and cell types, which is recognized as a safe and effective method for delivering therapeutic transgenes. AAV vector is the most popular viral gene delivery system in clinical delivery systems with unique and multiple advantages, such as ...
Ling Yin +6 more
wiley +1 more source
Recombinant viruses as tools to induce protective cellular immunity against infectious diseases [PDF]
, 2010 Infections by intracellular pathogens such as viruses, some bacteria and many parasites, are cleared in most cases after activation of specific T cellular immune responses that recognize foreign antigens and eliminate infected cells.
Alexandre Vieira Machado +3 more
core +2 more sources
Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics
Advanced Healthcare Materials, Volume 14, Issue 14, May 28, 2025.This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold +2 more
wiley +1 more source
Emerging Infectious DiseasesJYNNEOS, a third-generation smallpox vaccine, is integral to monkeypox virus (MPXV) control efforts, but the durability of this modified vaccinia Ankara–Bavarian Nordic (MVA-BN) vaccine’s effectiveness is undefined.
Kara Phipps +8 more
doaj +1 more source
, 2016 Abordamos el presente trabajo con el objetivo de realizar una revisión bibliográfica que nos permita elaborar un análisis del empleo de armas biológicas tanto en el pasado, es decir, una documentación de la utilización de éstas a lo largo de la historia,
Bruhn Cuevas, Rosa María
core +1 more source
Insights into poxviruses: virology and vaccines
Acta VirologicaDue to the successful eradication of smallpox worldwide and the cessation of smallpox vaccination campaign in 1980, the human population seems to be more susceptible to poxvirus infection.
Adriana Manuka +5 more
doaj +1 more source
Conservation and Variation in Orthopoxvirus Genome Structure
Journal of General Virology, 1979 Orthopoxvirus DNA from representative strains of rabbitpox, vaccinia, monkeypox, variola, cowpox and ectromelia viruses was analysed by cleavage with restriction endonucleases HindIII, XhoI or SmaI. Genome mol. wt. vary from about 120 x 10(6) for rabbitpox to about 145 x 10(6) for cowpox.
M, Mackett, L C, Archard
openaire +2 more sources
Serological study of vaccinia virus reservoirs in areas with and without official reports of outbreaks in cattle and humans in São Paulo, Brazil [PDF]
, 2013 Vaccinia virus (VACV), the etiological agent of an exanthematic disease, has been associated with several bovine outbreaks in Brazil since the end of the global vaccination campaign against smallpox. It was previously believed that the vaccine virus used
Acácia Ferreira Vicente +13 more
core +1 more source
(+)‐Camphor and (−)‐borneol derivatives as potential anti‐orthopoxvirus agents [PDF]
, 2021 А. С. Соколова +9 more
openalex +1 more source
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2005 Relata-se um surto de doença exantemática, caracterizada como varíola bovina, acometendo bovinos e seres humanos na Zona da Mata Mineira. Setenta e duas propriedades, distribuídas em 20 municípios localizados na região, foram visitadas para se levantar ...
Z.I.P. Lobato +8 more
doaj +1 more source