Results 101 to 110 of about 11,628 (248)
Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity [PDF]
, 2013 Virus infection of mammalian cells is sensed by pattern recognition receptors and leads to an innate immune response that restricts virus replication and induces adaptive immunity.
Benfield, C T O +6 more
core +1 more source
POTION: um software paralelizado para a detecção de grupos de genes homólogos sob evidência de seleção positiva em escala genômica. [PDF]
, 2020 O presente trabalho descreve o desenvolvimento do software POTION (POsitive selecTION) para a busca por grupos de genes homólogos sob evidência de seleção ...
HONGO, J. A., LOBO, F. P.
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Smallpox Infectious Disease [PDF]
, 2015 Smallpox is a disease similar to chicken pox, but not exactly the same. Smallpox is caused by a virus called Variola and is a member of the genus orthopoxvirus. The virus is a large brick shaped DNA virus. Smallpox spreads by direct, face to face contact
Allbee, Miranda, Smith, Brandon
core +1 more source
Viruses, 2017 Experimental intranasal infection of marmosets (Callithrix jacchus) with calpox virus results in fatal disease. Route and dose used for viral inoculation of the test animals mimics the natural transmission of smallpox, thus representing a suitable model ...
Anne Schmitt +7 more
doaj +1 more source
Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death. [PDF]
, 2017 Apoptosis is a genetically regulated cell suicide programme mediated by activation of the effector caspases 3, 6 and 7. If apoptotic cells are not scavenged, they progress to a lytic and inflammatory phase called secondary necrosis.
Alnemri, Diana +5 more
core +2 more sources
Orthopoxvirus Strains Defective in Surface Antigen Induction
Journal of General Virology, 1979 Various strains of vaccinia, variola, whitepox, monkeypox and cowpox viruses were examined for their capacity to induce a specific early antigen detectable on the surface of infected cells. The Elstree strain of vaccinia, two strains of variola minor and white variants of cowpox and monkeypox viruses lacked the capacity to induce the antigen. Variation
H, Amano, Y, Ueda, I, Tagaya
openaire +2 more sources
Cowpox with Severe Generalized Eruption, Finland
Emerging Infectious Diseases, 2003 Cowpox with a severe, generalized eruption was diagnosed in an atopic 4-year-old girl by electron microscopy, virus isolation, polymerase chain reaction, and immunoglobulin (Ig) M and low-avidity IgG antibodies.
Paula M. Pelkonen +7 more
doaj +1 more source
Human Monkeypox in Sierra Leone after 44-Year Absence of Reported Cases
Emerging Infectious Diseases, 2019 We note the reemergence of human monkeypox in Sierra Leone following a 44-year absence of reported disease. The persons affected were an 11-month-old boy and, several years later, a 35-year-old man.
Mary G. Reynolds +14 more
doaj +1 more source
Rapid evolution of protein kinase PKR alters sensitivity to viral inhibitors. [PDF]
, 2009 Protein kinase PKR (also known as EIF2AK2) is activated during viral infection and phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (eIF2), leading to inhibition of translation and viral replication. We report fast evolution
Dever, Thomas E +4 more
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