Serological study of vaccinia virus reservoirs in areas with and without official reports of outbreaks in cattle and humans in São Paulo, Brazil [PDF]
Vaccinia virus (VACV), the etiological agent of an exanthematic disease, has been associated with several bovine outbreaks in Brazil since the end of the global vaccination campaign against smallpox. It was previously believed that the vaccine virus used
Acácia Ferreira Vicente+13 more
core +1 more source
ABSTRACT Background Mpox, caused by the monkeypox virus (MPXV), is primarily recognized for its dermatologic and systemic symptoms. However, emerging evidence suggests a significant prevalence of gastrointestinal (GI) manifestations, particularly proctitis, diarrhea, nausea, vomiting, and abdominal pain.
Prakasini Satapathy+13 more
wiley +1 more source
In the present study we investigated the presence of infections by vaccinia-like viruses in dairy cattle from 12 counties in the state of Rio de Janeiro in the last 9 years.
Hermann G. Schatzmayr+11 more
doaj +1 more source
Revolution of AAV in Drug Discovery: From Delivery System to Clinical Application
ABSTRACT Adeno‐associated virus (AAV) is a non‐enveloped DNA virus infecting a wide variety of species, tissues, and cell types, which is recognized as a safe and effective method for delivering therapeutic transgenes. AAV vector is the most popular viral gene delivery system in clinical delivery systems with unique and multiple advantages, such as ...
Ling Yin+6 more
wiley +1 more source
An Increasing Danger of Zoonotic Orthopoxvirus Infections
On May 8, 1980, the World Health Assembly at its 33(rd) session solemnly declared that the world and all its peoples had won freedom from smallpox and recommended ceasing the vaccination of the population against smallpox. Currently, a larger part of the world population has no immunity not only against smallpox but also against other zoonotic ...
openaire +4 more sources
Identification of Novel Cetacean Poxviruses in Cetaceans Stranded in South West England [PDF]
Poxvirus infections in marine mammals have been mainly reported through their clinical lesions and electron microscopy (EM). Poxvirus particles in association with such lesions have been demonstrated by EM and were previously classified as two new ...
Barnett, J+8 more
core
Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics
This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold+2 more
wiley +1 more source
Titrage des anticorps contre le virus de la variole des dromadaires par la méthode de séroréduction des plages sur des cellules IB-RS2 [PDF]
Une méthode de séroréduction des plages, sur des cellules IB-RS2 en milieu liquide, a été mise au point et utilisée pour le titrage des anticorps contre le virus de la variole des dromadaires.
Nguyen Ba Vy,, Richard, Didier
core
Symmetrical diamidate prodrugs of nucleotide analogues for drug delivery [PDF]
The use of pronucleotides to circumvent the well-known drawbacks of nucleotide analogs has played a significant role in the area of antiviral and anticancer drug delivery.
McGuigan, Christopher+2 more
core +1 more source
Viral metagenomic analysis reveals potential biological hazards in non‐human primates in a zoo
The investigation identifies the presence of Encephalomyocarditis virus (EMCV), Baboon endogenous virus (BAV), Human endogenous retrovirus (HERV), and Baboon endogenous virus (BaEV) in non‐human primates (NHPs) at the Zoo, indicating potential zoonotic threats.
Ruiying Liang+13 more
wiley +1 more source