Results 101 to 110 of about 13,277 (283)

Low Specific T‐Cell Immunity Against Mpox Elicited in People With HIV‐1 and PrEP Users After Subcutaneous Vaccination Compared to Natural Infection

Journal of Medical Virology, Volume 97, Issue 7, July 2025.
ABSTRACT In August 2024, the World Health Organization declared mpox infection a Public Health Emergency of International Concern for second time since 2022 and recommended vaccinating all people at‐risk, such as people with HIV‐1 (PWH) and prophylaxis pre‐exposition (PrEP) users.
Olivia de la Calle‐Jiménez, Guiomar Casado‐Fernández, Inés Armenteros‐Yeguas, Luis Lemus‐Aguilar, Begoña Baza, Jorge Alfredo Pérez‐García, Javier Rodríguez‐Añover, Elena Mateos, Reynaldo Homen, Eva Orviz‐García, Noemí Cabello, Anabel Negredo, María Paz Sánchez Seco, Jorge del Romero, Vicente Estrada, Montserrat Torres, Mayte Coiras   +16 more
wiley   +1 more source

Mpox mRNA-1769 vaccine inhibits orthopoxvirus replication at intranasal, intrarectal, and cutaneous sites of inoculation

npj Vaccines
We previously reported that mice immunized twice with a lipid nanoparticle vaccine comprising four monkeypox viral mRNAs raised neutralizing antibodies and antigen-specific T cells and were protected against a lethal intranasal challenge with vaccinia ...
Catherine A. Cotter, Maxinne A. Ignacio, Jeffrey L. Americo, P. Earl, E. Mucker, Tiffany R. Frey, A. Carfi, J. Hooper, Alec W. Freyn, Bernard Moss   +9 more
semanticscholar   +1 more source

Interdisciplinary Approach to Monkeypox Prevention: Integrating Nanobiosensors, Nanovaccines, Artificial Intelligence, Visual Arts, and Social Sciences

Small Structures, Volume 6, Issue 7, July 2025.
This illustration depicts a comprehensive strategy against monkeypox, showcasing its transmission, symptoms, and prevention. Centralized around nanomaterials and biosensors, it integrates early screening, Internet of Things, vaccination, and community involvement through collaboration among healthcare workers, scientists, researchers, social groups ...
Vishal Chaudhary, Lucky Lucky, Harsh Sable, Nikhil Bhalla   +3 more
wiley   +1 more source

Proctitis and Other Gastrointestinal Manifestations in Mpox Disease: A Systematic Review and Meta‐Analysis

JGH Open, Volume 9, Issue 6, June 2025.
ABSTRACT Background Mpox, caused by the monkeypox virus (MPXV), is primarily recognized for its dermatologic and systemic symptoms. However, emerging evidence suggests a significant prevalence of gastrointestinal (GI) manifestations, particularly proctitis, diarrhea, nausea, vomiting, and abdominal pain.
Prakasini Satapathy, Abhay M. Gaidhane, Nasir Vadia, Soumya V. Menon, Kattela Chennakesavulu, Rajashree Panigrahi, Sanjit Sah, Suraj Tiwari, S. Govinda Rao, Khang Wen Goh, Rachana Mehta, Muhammed Shabil, Mahendra Singh, Ganesh Bushi   +13 more
wiley   +1 more source

Microparasites and their potential impact on the population dynamics of small cetaceans from South America: a brief review. Document SC/59/DW8, Scientific Committee, International Whaling Commission, Anchorage, Alaska, 4-14 May 2007 [PDF]

, 2007
We briefly review the pathology, epidemiology and molecular biology of cetacean viruses (including morbilli, papilloma and pox) and Brucella spp. encountered in South America.
Barrett, T., Crespo, E., Di Beneditto, A.P., Raga, J.A., Siciliano, S., Van Bressem, M.-F., Van Waerebeek, K.   +6 more
core  

The role of research in viral disease eradication and elimination programs: Lessons for malaria eradication [PDF]

, 2011
By examining the role research has played in eradication or regional elimination initiatives for three viral diseases-smallpox, poliomyelitis, and measles-we derive nine cross-cutting lessons applicable to malaria eradication.
Breman, JG, de Quadros, CA, Dowdle, WR, Foege, WH, Henderson, DA, John, TJ, Levine, MM   +6 more
core   +1 more source

Structural conservation and functional diversity of the Poxvirus Immune Evasion (PIE) domain superfamily [PDF]

, 2015
Poxviruses encode a broad array of proteins that serve to undermine host immune defenses. Structural analysis of four of these seemingly unrelated proteins revealed the recurrent use of a conserved beta-sandwich fold that has not been observed in any ...
Alcami, Alejo, Altekar, Altschul, Baker, Buatois, Bursill, Byun, Christopher Nelson, Clark, Dabbagh, Daved Fremont, Deane, Finn, Graham, Hendrickson, Hnatiuk, Jabari Elliott, Kelley, Kelley, Lalani, Lateef, Lateef, Lee, Lin, Loparev, McCoy, Megan Epperson, Ng, Pelham, Reading, Rozwarski, Ruiz-Arguello, Seet, Silverman, Smith, Sukrit Singh, Upton, Werden, White, Wilkins   +40 more
core   +3 more sources

Revolution of AAV in Drug Discovery: From Delivery System to Clinical Application

Journal of Medical Virology, Volume 97, Issue 6, June 2025.
ABSTRACT Adeno‐associated virus (AAV) is a non‐enveloped DNA virus infecting a wide variety of species, tissues, and cell types, which is recognized as a safe and effective method for delivering therapeutic transgenes. AAV vector is the most popular viral gene delivery system in clinical delivery systems with unique and multiple advantages, such as ...
Ling Yin, Hongliang He, Hongliang Zhang, Yuhua Shang, Chengbo Fu, Songquan Wu, Tengchuan Jin   +6 more
wiley   +1 more source

Desenvolvimento de software para a detecção de grupos de genes homólogos sob evidência de seleção positiva. [PDF]

, 2020
O presente trabalho descreve o desenvolvimento de um software para a busca por grupos de genes homólogos sob evidência de seleção positiva. Nesse trabalho, desenvolveu-se um software em perl para integrar diversos softwares de terceiros capazes de ...
HONGO, J. A., LOBO, F. P.
core  

Exceptional Clinical Resistance and Variable Reservoir Competence [PDF]

, 2018
Cowpox virus (CPXV) is a zoonotic virus and endemic in wild rodent populations in Eurasia. Serological surveys in Europe have reported high prevalence in different vole and mouse species.
Beer, Martin, Franke, Annika, Hoffmann, Donata, Keller, Markus, Osterrieder, Nikolaus, Ulrich, Rainer G., Weber, Saskia   +6 more
core   +1 more source