Results 181 to 190 of about 7,538 (211)
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Orthopoxvirus pan-genomic DNA assay
Journal of Virological Methods, 2007A genome-spanning assay is described that enables laboratory confirmation of infections with orthopoxviruses (OPVs), particularly Vaccinia, Monkeypox, and Variola viruses, which can cause vesiculo-pustular rash illnesses in humans. The assay uses a series of polymerase chain reaction (PCR) amplicons that overlap to span the approximately 200kilobase ...
Yu, Li +4 more
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The preparation of orthopoxvirus DNA
Journal of Virological Methods, 1981Abstract A method is presented for the preparation of cross-linked, intact orthopoxvirus DNA from viral cores extracted from virus-infected cell cultures.
J, Esposito, R, Condit, J, Obijeski
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2004
Biologic and antigenic properties are often useful for identifying and differentiating orthopoxviruses (OPV). However, polymerase chain reaction (PCR) amplification, with either restriction cleavage or sequencing of amplicons, has been gaining credibility as a more rapid, specific, sensitive, and often cost-saving technique for research and diagnostic ...
Hermann, Meyer +2 more
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Biologic and antigenic properties are often useful for identifying and differentiating orthopoxviruses (OPV). However, polymerase chain reaction (PCR) amplification, with either restriction cleavage or sequencing of amplicons, has been gaining credibility as a more rapid, specific, sensitive, and often cost-saving technique for research and diagnostic ...
Hermann, Meyer +2 more
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1990
Genetic analysis of orthopoxviruses has contributed substantially to our understanding of the functional organization of the poxvirus genome, and individual mutants provide invaluable tools for future studies of poxvirus biology. Deletion and transposition mutants, localized primarily in the termini of the genome, may be particularly useful for ...
R C, Condit, E G, Niles
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Genetic analysis of orthopoxviruses has contributed substantially to our understanding of the functional organization of the poxvirus genome, and individual mutants provide invaluable tools for future studies of poxvirus biology. Deletion and transposition mutants, localized primarily in the termini of the genome, may be particularly useful for ...
R C, Condit, E G, Niles
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Orthopoxvirus infection among wildlife in Zambia
Journal of General Virology, 2015(Uploaded by Plazi for the Bat Literature Project) Human monkeypox is a viral zoonosis caused by monkeypox virus, an orthopoxvirus (OPXV). The majority of human monkeypox cases have been reported in moist forested regions in West and Central Africa, particularly in the Democratic Republic of the Congo (DRC).
Orba, Yasuko +10 more
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Animal Models of Orthopoxvirus Infection
Veterinary Pathology, 2010Smallpox was one of the most devastating diseases known to humanity. Although smallpox was eradicated through a historically successful vaccination campaign, there is concern in the global community that either Variola virus (VARV), the causative agent of smallpox, or another species of Orthopoxvirus could be used as agents of bioterrorism. Therefore,
J L, Chapman +3 more
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Genus Orthopoxvirus: Monkeypox virus
2007Monkeypox virus is an orthopoxvirus that is genetically distinct from other members of the genus, including Variola virus, Vaccinia virus, Ectromelia virus, Camelpox virus, and Cowpox virus. It was first identified as the cause of a pox-like illness in captive monkeys in 1958.
Sandra Essbauer, Hermann Meyer
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Genus Orthopoxvirus: Cowpox virus
2007Cowpox virus (CPXV) is distinguished from other orthopoxvirus (OPV) species by producing cytoplasmic A-type inclusion bodies and flattened pocks with a hemorrhagic center on the chorioallantoic membrane. CPXV is endemic to Western Eurasia and naturally infects a broad range of host species including domestic animals, and zoo animals, as well as humans.
Sandra Essbauer, Hermann Meyer
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Smallpox and Other Orthopoxvirus Diseases
VacciTUTOR, 2022Smallpox was a severe disease causing substantial mortality among populations over several thousand years. It is caused by an orthopoxvirus, the variola (= smallpox) virus. Smallpox is a febrile disease with a maculo-, papulo-, vesicular and finally pustular rash, the typical pox lesions, numerous complications and a fatality rate of approximately 30%.
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